METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS
First Claim
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1. A method for coating or impregnating a non-organic surface with an antimicrobial agent, comprising:
- a) contacting the non-organic surface with an composition comprising an antimicrobial agent and a solvent; and
b) curing the non-organic surface at a temperature that is at least about 40°
C., wherein at least some of the solvent that was contacted with the surface is removed, and wherein the antimicrobial agent coats or impregnates the surface.
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Abstract
Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.
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Citations
67 Claims
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1. A method for coating or impregnating a non-organic surface with an antimicrobial agent, comprising:
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a) contacting the non-organic surface with an composition comprising an antimicrobial agent and a solvent; and
b) curing the non-organic surface at a temperature that is at least about 40°
C., wherein at least some of the solvent that was contacted with the surface is removed, and wherein the antimicrobial agent coats or impregnates the surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67)
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50. A method for coating or impregnating a medical device with an antimicrobial composition, comprising the steps of:
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a) contacting the medical device with a composition comprising an antimicrobial agent and a solvent;
b) curing the medical device at a temperature of about 40°
C. to about 80°
C. for about 12 hours to about 72 hours, wherein the medical device is dried;
c) washing the medical device with an aqueous composition; and
d) repeating step b), wherein the medical device becomes coated or impregnated with an antimicrobial composition.
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Specification