Multi-channel and multi dimensional system and method
First Claim
1. A medical instrument implanted in a patient'"'"'s body, which uses electrical and/or electromagnetic means of stimulation and/or inhibition (blocking) for the treatment of various diseases or specific states in a healthy person.
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Abstract
An implanted system for treatment of human diseases by electric stimulation and/or electric blocking of the body tissues, comprising sensor and/or biosensor means for measuring variables in the body, processor means connected to the sensors and biosensors for processing the measured variables and for deciding in real time whether to apply an electric signal to the body tissues, and electrode means implanted at predefined locations and connected to the processor means, for applying the stimulation and/or electric blocking signals to the body tissues. A method for treatment of human diseases using an implanted system by electric stimulation and/or electric blocking of the body tissues, comprising: A. measuring variables in the body using implanted sensor and/or biosensor means; B. processing the measured variables for deciding in real time whether to apply an electric signal to the body tissues; C. applying the stimulation and/or electric blocking signals to the body tissues.
173 Citations
152 Claims
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1. A medical instrument implanted in a patient'"'"'s body, which uses electrical and/or electromagnetic means of stimulation and/or inhibition (blocking) for the treatment of various diseases or specific states in a healthy person.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 21, 22, 23, 24, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 40, 41, 47, 48, 49, 50, 51, 52, 53, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 132, 133, 134, 135, 136, 137, 138, 139, 140, 152)
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2. The medical instrument according to claim 1, wherein the diseases include asthma, Agranulocytosis, Anemia, Atrophy of he optic nerve, Skin atrophy, Sardiac achalasia, Coagulation disorders, Buerger'"'"'s disease, Crohn'"'"'s disease, Pick'"'"'s disease, Raynaud'"'"'s disease, Vegetovascular dystony, Sudden cardiac arrest at sleep, Rectal prolapse, Flaccidly consolidating fractures, Hyperkeratosis, Hyperostosis, Adrenal cortex hyperfunction, Hypoglycemia, Subcortical dementia, Multi-infarction dementia Involuntary movements, Dyskinesia of the biliferous tracts, Dysmenorrhea (genital diseases), Dolichosigmoid, Stammering, Impotence, Leucosis, Migraine, Myodystrophy, Myopathy, Male and female infertility, Narcolepsy, Bauhin'"'"'s valve failure, Neurodermite, Obliterating atherosclerosis of the limbs'"'"' vessels, Obliterating endarteritis of the lower limbs'"'"' vessels, Alopecia, Paralyses of different etiology, Paresis of the vocal cords, Progressing myodystrophy, Psoriasis, Rickets, Zollinger-Ellison syndrome, Commissural disease, Huntington'"'"'s chorea, Chronic duodenal ileus, Chronic and acute hyperthermia, Chronic gastroenterocolitis, Chronic cholecystitis and cholecystopancreatitis, Chronic cystitis, Chronic glomerulonephritis, Chronic obstructive bronchitis, Chronic osteomyelitis, Chronic pyelonephritis, Cirrhosis, Eczema, Pulmonary emphysema, Enuresis and/or Duodenal ulcer,
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3. The medical instrument according to claim 1, wherein the specific states in a healthy person include dieting, losing wrinkles, restoring skin flexibility, dry skin, excessive perspiration, increasing the volume and power of muscles, enlarging or reducing breasts size.
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4. The medical instrument according to claim 1, comprising sensor means for measuring variables inside the body, processor means for processing the signals and issuing therapeutical signals, and electrodes for applying these signals, all implanted in the patient'"'"'s body, and wherein the sensor means include one or more of sensors and/or biosensors means.
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5. The medical instrument according to claim 1, wherein the processor means comprises digital computer means for processing information received from sensor means and for generating stimulation and/or inhibition therapeutical signals responsive to the received information, the therapeutical signals are transferred to electrodes by wire and/or wireless means, wireless means include RF/electromagnetic waves, the number of electrodes may vary between one to several hundred, and an electrode is used to apply a therapeutical signal to a target body tissue or nerve or organ.
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6. The medical instrument according to claim 1, wherein the characteristics of the applied signal are adjusted to effective values according to the disease or body state to be treated, preset parameters and signals received from the sensor means, these characteristics include the amplitude of the signal, its duration and/or frequency.
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7. The medical instrument according to claim 1, wherein the electrodes operate concurrently to apply signals to the patient'"'"'s body, each electrode may convey a separate signal from the processor means, and each signal is devised using a different algorithm, as suitable for a specific disease and a specific target organ.
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8. The medical instrument according to claim 1, wherein each electrode is be implanted in a different location in the body, to allow a plurality of electrodes to be implanted in various places, according to a patient'"'"'s disease or physiological situation to be treated.
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9. The medical instrument according to claim 1, wherein, for purposes of treatment of various diseases in one patient, the electric stimulator'"'"'s electrodes are simultaneously connected to different tissues, nervous structures, organs directly relating to each specific disease, while a separate channel or channels of the Electric Stimulator, its separate program or programs, separate non-interrelated algorithm or algorithms are used for treatment of each respective disease in the patient.
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10. The medical instrument according to claim 1, wherein the algorithms in the processor means are programmed in advance, and/or are updated in real time, the system may learn and adapt itself according to signals from the body, or may receive external programming signals.
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11. The medical instrument according to claim 1, wherein the activation oft the electrodes, under the processor'"'"'s control, occur in several modes, alternately or as set up:
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A. Automatic mode, using a feedback circuit comprising the sensor means, the processor and the electrodes;
B. On demand mode from a preset program stored in the processor C. Manual mode, initiated by patient or the physician.
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12. The medical instrument according to claim 1, wherein the information received by the sensor means is transferred to the processor, where it is processed according to the patient'"'"'s disease or physical state, and the processor selects only the sensors which are relevant in each case.
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13. The medical instrument according to claim 1, further including means for providing electrical power to the instrument, including an implanted primary or secondary battery, wherein the secondary battery may be recharged from an external source, connected for example through wires or wireless such as RF waves, and the system may include means for converting the body kinetic energy to electrical energy that may charge the battery.
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14. The medical instrument according to claim 1, further including one or more additional processors, each implanted in a different place in the body;
- an optional central processor collects and processes data from the various processors in the body.
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15. The medical instrument according to claim 1, wherein the electrode is implanted to affect systems and organs of the body including the nervous structure of the sympathetic nervous system or the parasympathetic system or the sympathetic nervous system and parasympathetic system and hypoglossal (sinocarotid collector of the Vegetative Nervous System-SCVNS), the central nervous system, as well as neurons of the organ and/or cutaneous nerves and/or depressor nerves.
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16. The medical instrument according to claim 15, wherein the electrode is implanted to affect a nervous band or group comprising all, or the majority of, the nerve branches innervating the carotid glome (glomus caroticum).
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21. The medical instrument according to claim 1, further including means for electric stimulation and/or blocking of the body tissues, comprising sensor means for measuring variables in the body, processor means connected to the sensors and biosensors for processing the measured variables and for deciding in real time whether to apply an electric signal to the body tissues, and electrode means implanted at predefined locations and connected to the processor means, for applying the stimulation and/or electric blocking signals to the body tissues.
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22. The medical instrument according to claim 1, wherein its sensors and biosensors located on the biologically inert coating thereof, contain, as an ingredient of their receptors, the porous conducting mineral Schungite with self-cleaning pores, while the sensors and biosensors are connected to the electric stimulator'"'"'s units.
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23. The medical instrument according to claim 1, wherein the Electric Stimulator has the surfaces of its shell and of the electrodes made to also host contacts, in addition to sensors and biosensors, which, when implementing algorithms of the Electric Stimulator'"'"'s program, enable to selectively connect either a certain number of the sensors, biosensors, contacts or all of them together to the Electric Stimulator'"'"'s units, thus creating a required configuration of the electrode(s), with a specific location and number of sensors, biosensors, this configuration being best adapted to accomplish the preliminarily set specific goals and objectives.
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24. The medical instrument according to claim 1, further including tiny metallic plates which send electrical signals, preferably at a high rate, towards a body tissue;
- This enables to measure the electrical resistance of the tissue and its changes responsive to activating signals from the instrument'"'"'s processor, before, during and after the activation of a therapeutic sequence;
this gives an indirect measurement of the patient'"'"'s body behavior.
- This enables to measure the electrical resistance of the tissue and its changes responsive to activating signals from the instrument'"'"'s processor, before, during and after the activation of a therapeutic sequence;
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26. The medical instrument according to claim 1, wherein the contacts of the Electric Stimulator can have different shapes which allows to connect them to both surfaces of the tissues, organs, and their internal structures.
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27. The medical instrument according to claim 1, wherein the the external coating of the Electric Stimulator may host from a few to thousands contacts, while each of the latter can be connected to either one, several or all channels of the Electric Stimulator.
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28. The medical instrument according to claim 1, wherein the contacts of the Electric Stimulator can have different shapes, sizes, locations, while each of the contacts may be connected to both one or a specific group of channels and all the channels together, and wherein The connection can be either algorithm-based or supported by the relevant design solution.
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29. The medical instrument according to claim 1, wherein the processor means contain all or part of the elements No. 1,2,3,5,6,8,9,10,11,14,15,16,17,18,19 as indicated in Table 1.
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30. The medical instrument according to claim 1, wherein the processor includes means for activating from one electrode up to several hundred electrodes, and wherein Each electrode may receive a different activating signal from the processor, according to a different algorithm, and/or for a different disease;
- The processor includes means for receiving signals from one sensor means, and up to several hundreds sensor means units, of one type or of various types.
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31. The medical instrument according to claim 1, wherein the processor may compute activating signals for one disease or for a plurality of diseases, up to several hundred diseases concurrently;
- the required signals are then applied to the patient'"'"'s organs through the electrodes;
the processor also decides, in each case, whether to apply stimulating or inhibiting signals, according to information from the sensor means and/or the clinical findings.
- the required signals are then applied to the patient'"'"'s organs through the electrodes;
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32. The medical instrument according to claim 1, wherein the Electric Stimulator has the feature that it has channels (units generating output pulses or units generating address codes, connected to the relevant electrodes) in the amount of 1 up to thousands, while each of these channels can be controlled with different algorithms of the programs.
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33. The medical instrument according to claim 1, wherein the Electric Stimulator'"'"'s shell contains the unit generating address codes and output pulses for the electrodes, connected to the electromagnetic communication unit of the implanted, enabling a wireless connection between the Electric Stimulator and with the implanted or non-implanted electrodes, while in order to support connection with the electrodes it is possible to use both individual address codes for each electrode and codeless non-address communication.
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34. The medical instrument according to claim 1, wherein the Electric Stimulator contains an option (a software option) to enable the Electric Stimulator'"'"'s programming and control functions by means of connecting telecommunications channels, including the Internet, radio channels, satellite communication channels, fiber optics communication channels, cellular telephone channels, etc, to the external radio-frequency communication unit or the internal radio-frequency communication unit of the Electric Stimulator.
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35. The medical instrument according to claim 1, wherein the Electric Stimulator contains means for controlling the duration and frequency of electric stimulation sessions can be carried our using the Electric Stimulator'"'"'s programmable microprocessor (unit(s) generating output pulses and/or the unit generating address codes and output pulses for the electrodes), or using the Electric Stimulator'"'"'s timer based on the signals sent by the sensors and/or biosensors of different types, while setting up the duration and frequency of electric stimulation sessions is effected separately, aided by different sensors and biosensors (for example, session duration is controlled with the respiration rate sensors, while the frequency is set up with the heart rate sensor).
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36. The medical instrument according to claim 1, wherein the Electric Stimulator contains means for activation of the channel(s) of its unit(s) generating output pulses and/or unit generating address codes and output pulses for the electrodes, as well as selection of the program(s) and algorithm(s) for stimulation and/or inhibition of functional activity of the body'"'"'s organs and tissues can be carried out in the three following modes (using each other separately, or in different combinations between them, the three together simultaneously):
- first mode,—
automatic mode set up in accordance with the type of signals transmitted by the sensors, biosensors to the Electric Stimulator'"'"'s units, as well as per the input algorithm(s) of the program(s);
second mode,—
set up regardless of the signals transmitted by the sensors, biosensors, depending on the input algorithm(s) of the program(s) only;
third mode,—
direct (voluntary) control of the above-mentioned functions and programs of the Electric Stimulator by the patient or doctor using the external radio-frequency communication unit of the Electric Stimulator or the internal radio-frequency communication unit thereof.
- first mode,—
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40. The medical instrument according to claim 1, wherein the Electric Stimulator or electric stimulators include means that allow the device to be controlled with one or several similar implanted electric stimulators, while all of the these “
- affiliated”
implanted electric stimulators are controlled with one main electric stimulator, that has the same units, but different algorithms.
- affiliated”
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41. The medical instrument according to claim 1, further including a noncontact communication channel with a receiver outside a patient'"'"'s body, and wherein the processor further includes means for sending the measured variables to the external receiver.
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47. The medical instrument according to claim 1, further including means for its being powered from electromagnetic waves transmitted by the external radio-frequency communication unit to the internal radio-frequency communication unit, and it also can be powered by the autonomous power supply unit capable of automatic recharging from the patient'"'"'s body kinetic energy.
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48. The medical instrument according to claim 1, further including autonomous power supply unit which is charged from the patient'"'"'s body kinetic energy, for which purpose this said power supply unit is connected with an electrode, via a transducer, to an adaptor converting mechanical motions of the diaphragmatic muscle occurring during the process of breathing into electric current—
- A flexible piezoelectric element (electrode-like) coated with a biologically inert material;
This element is implanted under the diaphragm'"'"'s cupola, from the right side, endoscopically, and it is connected to the chip;
The chip comprises an AC/DC transducer.
- A flexible piezoelectric element (electrode-like) coated with a biologically inert material;
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49. The medical instrument according to claim 1, wherein its unit or units for generating output pulses, as well as its unit generating address codes are programmable via the external radio frequency communication unit and via the internal radio frequency communication unit (or they are non-programmable while being operated via the above-mentioned communication units).
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50. The medical instrument according to claim 1, wherein, to increase the device'"'"'s safety level, it can be powered from the three following sources:
- autonomous power unit (battery), and/or kinetic energy of the patient'"'"'s body and/or by means of electromagnetic waves from the external non-implanted display, and/or remote control unit, while selecting of a source or sources is enabled by the algorithms of the software input into the Electric Stimulator, and/or remote control unit, and/or display.
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51. The medical instrument according to claim 1, wherein the processor is multifunctional, including means for its operation in one of several predefined modes.
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52. The medical instrument according to claim 1, wherein it includes means for a therapeutic effect applicable to treatment of diseases, and to correcting functional activity of the body'"'"'s systems, and/or organs and/or tissues in healthy persons, using the self-adjusting algorithms that adapts the device to current needs of the body, while these said algorithms can be selected with the remote control unit and/or display.
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53. The medical instrument according to claim 1, wherein it includes means for enabling the algorithm(s) of its program(s) to be changed in real-time depending on type of the signals sent by the sensors and/or biosensors, and due to this feature the optimal and most efficient algorithm of the program is selected, this being best adapted to the needs of the patient'"'"'s body in a specific period of time, to allow Dynamic, self-adjusting algorithms.
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60. The medical instrument according to claim 1, wherein the electrode means include a plurality of electrodes implanted in several locations in the patient'"'"'s body.
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61. The medical instrument according to claim 1, wherein, for purposes of stimulation and/or inhibition of the functional activity of the body'"'"'s systems, organs and tissues, electrically non-interconnected implanted electrodes of 0.13 microns up to 15 mm in size in the amount varying between 1 up to thousands are simultaneously used, while these said electrodes are connected to the electromagnetic communication unit in a wireless fashion, via electromagnetic and/or other waves or they are connected with wires to the unit generating output pulses and/or to the unit generating address codes and output pulses.
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62. The medical instrument according to claim 1, wherein the implanted or non-implanted electrodes connected to the electromagnetic communication unit of the Electric Stimulator in a wireless fashion, via electromagnetic and/or other waves contain, in their shell, the electromagnetic communication and power supply unit, the latter being connected, either directly or via the electrode'"'"'s decoder, to the unit generating output pulses, which in its turn is connected to a contact or contacts of the wireless electrode, while the electrode'"'"'s memory unit can also be connected to the unit generating output pulses, and the electrode'"'"'s power supply unit can be connected to all the above-mentioned units of the electrode.
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63. The medical instrument according to claim 1 wherein its shell can also simultaneously perform the function of an electrode or electrodes in addition to its main function;
- a “
Tablet-shape”
electric stimulator can be achieved.
- a “
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64. The medical instrument according to claim 1, wherein for purposes of electric stimulation or inhibition of functional activity of the body'"'"'s systems, organs and tissues;
- electrodes of different shapes varying in number of current conducting cores (wires) and contacts (channels) are used, while these electrodes are connected, either in a wireless fashion or with wires, to the unit generating output pulses or to the electromagnetic communication unit of the Electric Stimulator.
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65. The medical instrument according to claim 1 further including an audio and/or light, and/or vibration, and/or temperature, and/or cutaneoelectric indicating device providing the patient with data on conditions of the Electric Stimulator, his/her own body, as well as with other information transmitted by the external and/or internal radio-frequency communications units to the Electric Stimulator, is connected to the unit generating output pulses, and/or to the unit generating address codes and output pulses for the electrodes, and/or to the internal radio-frequency communication unit, and/or to the external radio-frequency communication unit, and/or to an electrode, and/or to electrodes.
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66. The medical instrument according to claim 1, further including in addition to analyzing functional activity of the body'"'"'s systems, and/or organs, and/or tissues, as well as controlling and analyzing operation and functioning of the implanted Stimulator, the monitor also supports programming or reprogramming of the Electric Stimulator (by means of a computer connected thereto via the radio-frequency communication unit).
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67. The medical instrument according to claim 1, further including means for running a long-term monitoring of functional activity of the body'"'"'s systems, organs, tissues, and operation of the Electric Stimulator;
- while duration of the monitoring may vary between several minutes and several months.
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68. The medical instrument according to claim 1, further including External Non-Implanted Display-Programmer—
- Charging Device and wherein the sensors and biosensors representing micro- and macro-indicating devices of different, located both on the patient'"'"'s body surface and directly introduced into its tissues, organs, systems (for example, arterial pressure meter introduced into the femoral artery) collect data on functioning of the body'"'"'s systems, and wherein these data are transmitted to the unit analyzing conditions of the body'"'"'s systems, organs, tissues (No. 3 on the Diagram). The unit separately analyzes functioning of each of the systems studied enabling both fragmentary and permanent real-time monitoring of the body'"'"'s systems, organs, tissues.
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69. The medical instrument according to claim 1, further including means to recharge the battery of the Electric Stimulator, and/or to program the latter via the Unit No. 4.
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70. The medical instrument according to claim 1, wherein the means for covering the processor (chip) from the outside include a Silicon coating.
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71. The medical instrument according to claim 1, wherein the means for covering the processor (chip) from the outside include a Silicon mixed with Shungite.
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72. The medical instrument according to claim 1, wherein the means for covering the processor (chip) from the outside include Silicon completely covered on the outside with Shungite.
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73. The medical instrument according to claim 1, wherein the electric stimulator include coating means that are external biologically inert coating is made of a silicon compound whose molecular mass varies between a few and a thousand units, while this coating can host sensors, biosensors, contacts connected to the Electric Stimulator'"'"'s units.
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74. The medical instrument according to claim 1, wherein the means for covering the processor (chip) are external biologically inert coating is made of a porous material, while the pores-size varies between a few nanometers and a few micrometers, and the pores themselves are evenly spread all over the entire coating surface with their concentration on one square millimeter.
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132. The medical instrument according to claim 1, wherein its external radio-frequency communication unit can be connected to the external non-implanted display monitoring conditions of the body'"'"'s systems, organs;
- tissues, and the non-implanted or temporarily implanted into the patient'"'"'s body sensors and biosensors are connected thereto;
while the data on the body'"'"'s systems are transmitted from the display, via the internal radio-frequency communication unit, to the implanted Electric Stimulator'"'"'s units, being additional to and/or replacing the data, received by these said units from the implanted sensors and biosensors.
- tissues, and the non-implanted or temporarily implanted into the patient'"'"'s body sensors and biosensors are connected thereto;
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133. The medical instrument according to claim 1, further including sensors usable as catheter means without electrode:
- the received data can be displayed using any display means, A Non-Implanted External Display may be used that, according to Clause B above, has the following distinct feature;
it allows to monitor functional activity of the respiratory;
digestive, cardiovascular, nervous, immune, urinary and/or temperature control systems, while both the implanted or non-implanted sensors and biosensors of the Display or Electric Stimulator can be used for this purposes.
- the received data can be displayed using any display means, A Non-Implanted External Display may be used that, according to Clause B above, has the following distinct feature;
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134. The medical instrument according to claim 1, further including an option that allows additional, both implanted and non-implanted units to be connected thereto.
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135. The medical instrument according to claim 1, further including additional non-implanted units which are connected to the Electric Stimulator via the external radio-frequency communication unit and internal radio-frequency communication unit, while the additional implanted units, which are connected to the Electric Stimulator'"'"'s shell, units or electrodes, such connection being made with electrode(s) or without them;
- using plug-and-socket units.
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136. The medical instrument according to claim 1, wherein each of its main units can be both implanted and non-implanted, while being connected to the remaining units of the Electric Stimulator, found in the shell or electrode(s) thereof via the external radio-frequency communication unit, internal radio-frequency communication unit (for the non-implanted units), or with an electrode or plug-and socket unit(s) (for the implanted ones).
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137. The implanted system according to claim 1, further including a noncontact communication channel with a transmitter outside a patient'"'"'s body, and wherein the processor is programmable, including means for loading a working program therein from the external transmitter.
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138. The medical instrument according to claim 1, wherein the diseases include Asthma, Insomnia, Hypersonmia, Apnea, Narcolepsy, Sudden cardiac arrest at sleep, Paresis of the vocal cords, Nervous anorexia, Obesity, Bulimia, Gastric and duodenal ulcer, Chronic gastroenterocolitis, Refluxesophagitis, Gastrointestinal dyskinesia. Commissural disease, Crohn'"'"'s disease, Hirschsprung'"'"'s disease—
- megacolon, Rectal prolapse, Chronic duodenal ileus, Bauhin'"'"'s valve failure, Doloichosigmoid. Chronic intestinal obstruction (commissural disease, megacolon, chronic mesenterial circulation insufficiency, metacolon, doloichosigmoid, cardiac achalasia, Schizophrenia with schizophrenic affective disorders and delirium, Anxiety and depression, Borderline personality disorder, Emphysema Cortical dementia-Alzheimer'"'"'s disease. Pick'"'"'s disease, Subcortical dementia-supranuclear palsy (paralysis), Huntington'"'"'s chorea Parkinson'"'"'s disease, Multiinfarction dementia. Involuntary movements, Stammering and/or Epilepsy.
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139. The medical instrument according to claim 1, wherein the diseases include Priapism, Infantile cerebral paralysis Paralyses of different etiology Syringomyelia, Progressing myodystrophy and other forms of dystrophy, Chronic and acute hyperthermia Atrophy of the optic nerve, Chronic periodic pains (angina pectoris, phantom pains, neuritis, nerve root syndromes Terminalstage pains Migraine, Cancer pain, Hypertension, Hypotension Vegetovascular dystony, Diabetes, hypoglycemia, diabetes insipidus hypothyrosis, hyperthyrosis adrenal cortex insufficiency, male and female infertility, impotence, adrenal cortex hyperfunction, dysmenorrhea, Zollinger-Ellison syndrome. Dyskinesia of the biliferous tracts. Chronic hepatitis. Chronic cholecystopancreatitis, Cirrhosis, Osteoporosis, Periostitis;
- osteosclerosis of different types, Hyperostosis, Chronic osteomyelitis Flaccidly consolidating fractures and/or Rickets.
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140. The medical instrument according to claim 1, wherein the diseases include Perthes disease, anemia, agranulocytosis, leucosis. Immunodeficiency trauma-related paralyses, myodystrophy;
- myopathy, Bodybuilding Hydronephrosis. Chronic pyelonephritis, Chronic glomerulonephritis, Urinary bladder atony, Chronic cystitis, Psoriasis, Neurodermite, Eczema, Alopecia, Hyperkeratosis, Skin atrophy, Angiotrophoneurosis, Drug addiction. Alcoholism, Obliterating atherosclerosis and endarteritis, Ischemic heart disease and angina pectoris, Cardiac arrhythmia, Raynaud'"'"'s disease, Buerger'"'"'s disease, Chronic thrombophlebitis-supranuclear palsy (paralysis) and/or Postthrombophlebitic syndrome.
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152. The medical instrument according to claim 4, wherein the electrode is implanted to affect systems and organs of the body including the nervous structure of the sympathetic nervous system or the parasympathetic system or the sympathetic nervous system and parasympathetic system and hypoglossal (sinocarotid collector of the Vegetative Nervous System-SCVNS), the central nervous system, as well as neurons of the organ and/or cutaneous nerves and/or depressor nerves.
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2. The medical instrument according to claim 1, wherein the diseases include asthma, Agranulocytosis, Anemia, Atrophy of he optic nerve, Skin atrophy, Sardiac achalasia, Coagulation disorders, Buerger'"'"'s disease, Crohn'"'"'s disease, Pick'"'"'s disease, Raynaud'"'"'s disease, Vegetovascular dystony, Sudden cardiac arrest at sleep, Rectal prolapse, Flaccidly consolidating fractures, Hyperkeratosis, Hyperostosis, Adrenal cortex hyperfunction, Hypoglycemia, Subcortical dementia, Multi-infarction dementia Involuntary movements, Dyskinesia of the biliferous tracts, Dysmenorrhea (genital diseases), Dolichosigmoid, Stammering, Impotence, Leucosis, Migraine, Myodystrophy, Myopathy, Male and female infertility, Narcolepsy, Bauhin'"'"'s valve failure, Neurodermite, Obliterating atherosclerosis of the limbs'"'"' vessels, Obliterating endarteritis of the lower limbs'"'"' vessels, Alopecia, Paralyses of different etiology, Paresis of the vocal cords, Progressing myodystrophy, Psoriasis, Rickets, Zollinger-Ellison syndrome, Commissural disease, Huntington'"'"'s chorea, Chronic duodenal ileus, Chronic and acute hyperthermia, Chronic gastroenterocolitis, Chronic cholecystitis and cholecystopancreatitis, Chronic cystitis, Chronic glomerulonephritis, Chronic obstructive bronchitis, Chronic osteomyelitis, Chronic pyelonephritis, Cirrhosis, Eczema, Pulmonary emphysema, Enuresis and/or Duodenal ulcer,
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17. A medical treatment method using an instrument implanted in a patient'"'"'s body, which uses electrical and/or electromagnetic means of stimulation and/or inhibition for the treatment of various diseases or specific states in a healthy person.
- View Dependent Claims (18, 19, 20, 25, 37, 38, 39, 42, 43, 44, 45, 46, 54, 55, 56, 57, 58, 59, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 148, 149, 150)
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18. The medical treatment method according to claim 17 which, for stimulating and/or inhibiting the functional activity of the body'"'"'s systems and separate organs and tissues, uses pulse currents of parameters as detailed in the present disclosure.
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19. The medical treatment method according to claim 17 which, in order to control functioning of the implanted stimulator and to set its optimal mode, further including the step where the patient is connected (for the period varying between 1 and several days) to a portable external non-implantable monitor collecting and analyzing data on the Electric Stimulator'"'"'s work, as well as data on a functional condition of the body'"'"'s systems, organs, and tissues, while this said monitor comprises a unit analyzing functional conditions of the body'"'"'s systems, organs, and tissues, connected to the sensor means, and this unit is also connected to the monitor'"'"'s unit of radio-frequency communication with the Electric Stimulator'"'"'s external radio-frequency communication unit which, in its turn, is connected to a computer via a radio-frequency channel, as well as to the autonomous power supply unit, the latter also being connected to all the above-detailed units of the monitor.
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20. The medical treatment method according to claim 17 further including the step, performed using the Electric Stimulator'"'"'s software, of distinguishing between the changes in functional activity of the body'"'"'s systems, and/or organs, and/or tissues typical of an onset of a disease (symptoms) and the changes in functional activity of the body'"'"'s systems, and/or organs, and/or tissues, that are not related to symptoms of a disease, but typically occur in the patient'"'"'s body, while the Electric Stimulator'"'"'s “
- learning”
of this process is aided by a non-implanted display.
- learning”
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25. The medical treatment method according to claim 17 wherein, using electrical measurements, use changes in resistance, which are compared with the readings from the sensor means;
- The system thus learns the correlation between the sensor means readings and the indirect measurements;
when the original sensor means eventually are put out of use because of organic matter deposits thereon, the indirect measurements can still be used to evaluate the body'"'"'s conditions;
the system thus includes a structure with means for learning the patient body'"'"'s characteristics;
a method for learning these characteristics and replacing the original sensor means with indirect sensors has been disclosed.
- The system thus learns the correlation between the sensor means readings and the indirect measurements;
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37. The medical treatment method according to claim 17, wherein, using means in the Electric Stimulator that makes it resemble the natural functioning of separate nervous centers and the entire human nervous system, further include the step, in addition to the existing involuntary algorithms and programs, controlling functions of the systems and organs, there is also an option to voluntarily control a number of the body'"'"'s organs and systems (for example, voluntary regulation of respiration rate, breath depth, etc.)
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38. The medical treatment method according to claim 81, wherein the Electric Stimulator and Therapy Method has two following modes of operation, an they can be activated both simultaneously and separately:
- First Mode—
supports regular (preventive) electric stimulation sessions for the prevention of acute symptoms of the disease;
Second Mode—
supports therapeutic electric stimulation sessions, and it is activated when acute symptoms of the disease (attacks, seizures, etc.) occur;
As a result, as it also in the case of the First Mode, functional activity of the body'"'"'s systems, and/or organs, and/or tissues is stimulated and/or inhibited.
- First Mode—
-
39. The medical treatment method according to claim 17, wherein, in order to assess efficiency of the implanted Stimulator, functional activity of the body'"'"'s systems, and/or organs, and/or tissues is studied before conducting electric stimulation sessions and thereafter using the sensors, biosensors as well as the methods widely used in the common clinical practice, while a detected decrease in the functional activity of the body'"'"'s systems, and/or organs, and/or tissues is deemed an inhibition symptom, while an enhancement thereof is considered to be a symptom of stimulation of the functional activity of the body'"'"'s systems, and/or organs, and/or tissues.
-
42. The medical treatment method according to claim 17, wherein a change of the stimulation mode (stimulation session frequency and session duration) depend on the sensor'"'"'s signal value (that, in its turn, depends on a particular time period of the day, the patient'"'"'s activity, and severity of symptoms of the disease).
-
43. The medical treatment method according to claim 17, further including the step of Accurate adaptation of the stimulation mode to individual physical activity of the patient'"'"'s body or to a symptoms severity degree of any specific ailment.
-
44. The medical treatment method according to claim 17, further including an increase or reduction of current, voltage, output pulses duration, and stimulation sessions frequency and duration by increasing or reducing signals of biological sensors, wherein:
-
1) Biological sensors are located directly on the chip and electrode housing;
2) The majority of chip units are connected with its radiofrequency communication component, which enables a direct control and adaptability thereof by means of the external programming unit;
3) Stimulation sessions and intervals of determining the nerve electric activity proceed in succession and not concurrently;
4) The chip operation modes are programmed by external programming unit (setup of simulation thresholds, working algorithms, etc.);
5) Power battery of the stand-alone power unit is charged by the following two sources;
external programming unit, and bioelectric activity of nerve;
power supply to the chip can be provided by electromagnetic waves transmitted from the external programming unit;
6) To add reliability, onset of seizure or deterioration of other ailment symptoms are identified according to a set of parameters;
7) Indicator informs the patients, when the stimulation device starts and finishes working.
-
-
45. The medical treatment method according to claim 17, further including an increase or reduction of current, voltage, output pulses'"'"' duration, and stimulation sessions frequency and duration by increasing or reducing signals of biological sensors, wherein:
-
1) Increase or reduction of current, voltage, output pulses duration, and stimulation sessions frequency and duration via each channel depending on an increase or reduction of signals of sensors and biological sensors;
2) Changing of sequence and combination of activated chip channels depending on the biosensors'"'"' signals values;
3) A parallel control of several organs using various stimulation programs to resume their functions;
4) Biosensors design, concurrent monitoring of the state of several body organs and systems;
5) Use of at least two isolated channels to control each organ or system in order to provide a concurrent effect on several nerve centers and optimize the results of treatment.
-
-
46. The medical treatment method according to claim 17, further including an increase or reduction of current, voltage, output pulses duration, and stimulation sessions frequency and duration by increasing or reducing signals of biological sensors, wherein:
-
1) Increase or reduction of current, voltage, output pulses duration, and stimulation sessions frequency and duration via each channel depending on an increase or reduction of signals of sensors and biological sensors;
2) Changing of sequence and combination of activated chip channels depending on the current state of stimulated organs and tissues, as determined by biosensors;
3) Wireless implantable families of secondary microelectrodes with individual programming of operation modes and parent chip connection by means of electromagnetic waves;
4) Biosensors design;
5) Monitoring of body systems and functions by means of various biological sensors, 6) Concurrent stimulation of over 100 nerves, organs, and muscles using various programs with a parallel monitoring of the results.
-
-
54. The medical treatment method according to claim 17, wherein its external radio-frequency communication unit and the internal radio-frequency communication unit enable and support a reciprocal connection between external non-implanted devices and each of the Electric Stimulator'"'"'s units and/or channels separately, while address codes may be used for this purpose.
-
55. The medical treatment method according to claim 17, wherein a Therapy Method and Method for Correction of Functional Activity of the Body'"'"'s Systems, and or Organs;
- and/or Tissues are used to identify, to detect certain conditions of the body using the sensors and biosensors, one or several indirect parameters may be considered, these parameters being typical of each specific patient;
in order to identify these typical indirect properties, functional activity of the body'"'"'s systems, organs, tissues is repeatedly (twice and up to several times) examined and analyzed when the above-mentioned conditions become pronounced using the display;
or applying the methods and equipment widely used in the clinical practice, thus establishing regular changes in the selected homeostatic parameters, which are to be taken into account for purposes of identification of the above-mentioned conditions at a later stage.
- and/or Tissues are used to identify, to detect certain conditions of the body using the sensors and biosensors, one or several indirect parameters may be considered, these parameters being typical of each specific patient;
-
56. The medical treatment method according to claim 109, wherein upon development of the hypoglycemic coma in one of the patients, the following repeated regular changes are observed:
- a drop in the arterial pressure of at least 20 mm of the mercury column, a minimal pulse acceleration of 30 beats per minutes a 30% acceleration of the respiration rate, while these changes typically coincide with a drop in the blood glucose level amounting to 50% deviation from the norm.
-
57. The medical treatment method according to claim 17, wherein to obtain the maximal therapeutic effect, prior to using the Electric Stimulator, the patient is examined in order to detect typical disease-related phenomena, this being followed by the development of individual programs and algorithms of the Electric Stimulator aimed at correcting main adverse effects of the disease(s).
-
58. The medical treatment method according to claim 17, wherein general coordination of interrelated operation of all the channels, and control of functional activity of the body'"'"'s systems, and/or organs, and/or tissues with stimulation and/or inhibition via the above-mentioned channels, is supported with a separate (main) algorithm (a “
- visceral conductor”
) of the program, while this said algorithm can flexibly perform real-time changes thus optimally adapting the Electric Stimulator'"'"'s channels to current needs of the patient body.
- visceral conductor”
-
59. The medical treatment method according to claim 17, wherein the function of algorithms in the software of the unit(s) generating output pulses, or of the unit generating address codes and output pulses for the electrodes is based on identification of code signals sent by sensors and biosensors of various types, while each of these signals reflects a singular specific condition of the patient and or his/her body'"'"'s systems, and/or organs, and/or tissues (for example, Code 1 sent by Sensor No. 1 identifies the patient'"'"'s condition during night time, when a spasm of the bronchi is at an onset, and, as a result wheezing in the lung appears, while Code 2 sent by Sensor 1 reflects the patient'"'"'s condition during night time when no asphyxia attack and spasm of the bronchi occur), and by means of analyzing such codes Electric Stimulator'"'"'s CPU generates commands to activate and/or deactivate electric stimulation through one or several channels, commands to set the optimal current parameters, stimulation modes, aimed at obtaining physiological effects of the stimulation and/or inhibition of functional activity of the body'"'"'s systems, and/or organs, and/or tissues (object-oriented functional programming).
-
75. The medical treatment method according to claim 17, wherein, in order to obtain a therapeutic effect, the electrode or electrodes of the Electric Stimulator are implanted into the subcutaneous fat, and/or into nerves (vagus nerve and or sinocarotid), and/or into various organs and/or into blood vessels and/or into the spinal cord, and/or into bones or into the medullar canal, are connected to different areas of the skin with the Electric Stimulator being implanted, in accordance with specific treatment techniques for each of the diseases.
-
76. The medical treatment method according to claim 17, wherein the electrode is implanted to affect systems and organs of the body including the nervous structure of the sympathetic nervous system or the parasympathetic system or the sympathetic nervous system and parasympathetic system and hypoglossal (sinocarotid collector of the Vegetative Nervous System-SCVNS), the central nervous system, as well as neurons of the organ and/or cutaneous nerves and/or depressor nerves.
-
77. The medical treatment method according to claim 17, wherein the electrode is implanted to affect a nervous band or group comprising all, or the majority of, the nerve branches innervating the carotid glome (glomus caroticum).
-
78. The medical treatment method according to claim 17, wherein the electrode is implanted to affect systems and/or organs of the body as indicated in Tables 1 to 19 of the present disclosure.
-
79. The medical treatment method according to claim 17, wherein the method of treatment by electro-stimulator as applied for treating Asthma, using one or more electrodes as detailed in claim X, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
-
Best mode—
right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11);
while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs nervous centers;
Murmur sensor (heart, lungs;
intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues Biosensor of sugar contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
-
-
80. The medical treatment method according to claim 17, wherein treatment by electro-stimulator for treating Epilepsy, using one or more electrodes wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
-
Best mode—
right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
left Vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right Vagus nerve (in the superior third of the neck, at the level C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter. Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs;
nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues. Biosensor of sugar contents in the blood, Biosensor of hormone contents in the blood, Biosensor of alcohol contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
-
-
81. The medical treatment method according to claim 17, wherein for treating Obesity, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
-
Best mode—
Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) or Second best mode—
left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) and/or right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) while using the following sensors;
Arterial pressure meter. Heart rate meter. Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Gastric juice acidity sensor, while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
-
-
82. The medical treatment method according to claim 17, wherein for treating Hypertension, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
Best mode—
Right depressor nerve (over the aortic arch or in the middle third of the neck) and/or left depressor nerve (over the aortic arch or in the middle third of the neck) or Second best mode—
Right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms. Amplitude of current pulses;
0.02-1 V.
-
83. The medical treatment method according to claim 17, wherein for treating Diabetes, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) or Second best mode—
Left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) and/or right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) while using the following sensors;
Arterial pressure meter, Heart rate meter;
Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers Murmur sensor (heart, lungs;
intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood. Biosensor of hormone contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
84. The medical treatment method according to claim 17, wherein for treating Angina Pectoris, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
Spinal cord (at the level T10-T-12) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine);
while using the following bio-sensors;
Biosensor of oxygen contents in the tissues and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
85. The medical treatment method according to claim 17, wherein for treating Alcoholism, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right depressor nerve, (over the aortic arch or in the middle third of the neck) and/or left depressor nerve (over the aortic arch or in the middle third of the neck) or Second best mode—
Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or Nerve collector of the organ (skin) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter. Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues. Biosensor of sugar contents in the blood. Biosensor of alcohol contents in the blood Biosensor of narcotic substances contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms.Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
86. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Drug addiction, using one or more electrodes as detailed in claim X, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
-
Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or Left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) and/or right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or Right sympathetic trunk;
cervical (in the superior third of the neck, at the level C2-C3) or Left sympathetic trunk (Left upper cervical third part between C2-C3) and/or right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or Spinal cord and/or right depressor nerve (over the aortic arch or in the middle third of the neck) and/or left depressor nerve (over the aortic arch or in the middle third of the neck) and/or Nerve collector of the organ while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter. Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood, Biosensor of alcohol contents in the blood. Biosensor of narcotic substances contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
-
-
87. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Parkinson'"'"'s disease, using one or more electrodes as detailed in claim X, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Left sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or right sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues Biosensor of sugar contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms.Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
88. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Alzheimer'"'"'s disease, using one or more electrodes as detailed in claim X, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Left sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or right sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissuesBiosensor of sugar contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
89. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Gastric ulcer, using one or more electrodes as detailed in claim X, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body, Best mode—
- Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3), or Second best mode—
Left Sympathetic trunk, thoracic (in the superior third, at the level, T7-T-11) and/or right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Gastric juice acidity sensor, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues. Biosensor of sugar contents in the blood. Biosensor of hormone contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3), or Second best mode—
-
90. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Pain syndromes of different genesis, using one or more electrodes, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Spinal cord (at the level T10-T-12) or Second best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter Heart rate meter. Respiration rate meter. Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine)while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms.Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
91. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Osteoporosis, using one or more electrodes, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Nerve collector of the organ (parathyroid gland, muscles) or Second best mode—
Nerve collector of the organ (muscles) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
92. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Constipation, using one or more electrodes, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sympathetic trunk;
cervical (in the superior third of the neck, at the level C2-C3) and/or Left sympathetic trunk (Left upper cervical third part between C2-C3) or Second best mode—
Right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or Left vagus nerve (in the superior third of the neck, at the level C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
93. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Apnea, using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sympathetic trunk, cervical (in the superior third of the neck, at the level C2-C3) and/or Left sympathetic trunk (Left upper cervical third part between C2-C3) or Second best mode—
Spinal cord (at the level T10-T-12) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
94. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Insomnia, using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
Right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or left vagus nerve (in the superior third of the neck, at the level C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter. Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers Murmur sensor (heart;
lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissuesand while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
95. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Hypersomnia, using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sympathetic trunk, cervical (in the superior third of the neck, at the level C2-C3) and/or Left sympathetic trunk (Left upper cervical third part between C2-C3) or Second best mode—
Spinal cord (at the level T10-T-12) while using the following sensors;
Arterial pressure meter, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine) while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
96. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Obliterating vascular diseases of the limbs, using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Spinal cord (at the level T10-T-12) or Second best mode—
right sympathetic trunk, thoracic (in the superior third;
at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third at the level T7-T-11) while using the following sensors;
Arterial pressure meter, Heart rate meter Respiration rate meterAngular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
97. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Urinary bladder atony using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Nerve collector of the organ (v. bladder) or Second best mode—
Spinal cord (at the level T10-T-12) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter;
Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
98. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Ailments associated with a malfunction of the rectum sphincters, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Nerve collector of the organ (rectum) while using the following sensors, Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms. Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
99. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Bulimia, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or left vagus nerve (in the superior third of the neck, at the level C2-C3) or Second best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk thoracic (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter Temperature gage Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers. Gastric juice acidity sensor, Murmur sensor (heart, lungs, intestine) while using the following bio-sensors-Biosensor of oxygen contents in the tissues Biosensor of sugar contents in the blood, Biosensor of hormone contents in the blood, and while the electro-stimulation parameters are as follows-Current frequency;
1-300 HZ. Duration of current pulses-0.1-0.8 Ms. Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
100. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Reflux-esophagitis:
- using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body;
Best mode—
Right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or left vagus nerve (in the superior third of the neck, at the level C2-C3) or Second best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers, Gastric juice acidity sensor;
Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8, Ms, Amplitude of current pulses;
0.02-1 V.
- using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body;
-
101. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Infantile cerebral paralysis using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Spinal cord (at the level T10-T-12) and Nerve collector of the organ (Muscles) or Second best mode—
Nerve collector of the organ (Muscles) while using the following sensors;
Arterial pressure meter. Heart rate meter;
Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine) while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms.Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
102. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Posttraumatic paralysis using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Spinal cord (at the level T10-T-12) and Nerve collector of the organ (Muscles) or Second best mode—
Nerve collector of the organ (Muscles) while using the following sensors, Arterial pressure meter. Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart, lungs, intestine, while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
103. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Hirschsprung'"'"'s disease using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) and/or right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) or Second best mode—
Nerve collector of the organ (colon) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart;
lungs;
intestine) while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
104. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Depression using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
right sympathetic trunk, cervical (in the superior third of the neck, at the level C2-C3) and/or left sympathetic trunk (Left upper cervical third part between C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissuesBiosensor of sugar contents in the blood and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
105. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Schizophrenia, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs). Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the bloodand while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms.Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
106. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Borderline personality disorders using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine, while using the following bio-sensors;
Biosensor of oxygen contents in the tissues. Biosensor of sugar contents in the bloodand while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms.Amplitude of current pulses-0.02-1 V.
- Best mode—
-
107. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Nervous anorexia using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sinocarotid collector (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector (over the bifurcation spot of the common carotid artery) or Second best mode—
right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter, Heart rate meter. Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8. Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
108. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Adrenal cortex hypofunction (Addison'"'"'s disease), using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) or Second best mode—
Nerve collector of the organ while using the following sensors;
Arterial pressure meter;
Heart rate meter, Respiration rate meter Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood. Biosensor of hormone contents in the bloodand while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
109. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Adrenal cortex insufficiency using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) or Second best mode—
Nerve collector of the organ while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter. Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues. Biosensor of sugar contents in the blood, Biosensor of hormone contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
110. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Hypothyrosis using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Left sympathetic trunk (Left upper cervical third part between C2-C3) and/or right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) or Second best mode—
Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of hormone contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
111. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Progressing myodystrophy, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Spinal cord (at the level T10-T-12) and Nerve collector of the organ (Muscles) or Second best mode—
Nerve collector of the organ (Muscles) while using the following sensors;
Arterial pressure meter. Heart rate meter. Respiration rate meter, Temperature gage Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart;
lungs, intestine) while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
112. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Angiotrophone neurosis, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Spinal cord (at the level T10-T-12) or Second best mode—
Nerve collector of the organ (Muscles) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissuesand while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms.Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
113. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Syringomyelia, using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third;
at the level T7-T-11) or Second best mode—
Right sympathetic trunk, cervical (in the superior third of the neck, at the level C2-C3) and/or left sympathetic trunk (Left upper cervical third part between C2-C3) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter. Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissuesand while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
114. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Impotence, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Nerve collector of the organ (skin) while using the following sensors;
Arterial pressure meter, Heart rate meter Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs) Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood. Biosensor of alcohol contents in the blood, Biosensor of narcotic substances contents in the bloodand while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
115. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Paresis of the vocal cords, using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Left vagus nerve (in the superior third of the neck, at the level C2-C3) and/or right vagus nerve (in the superior third of the neck, at the level C2-C3) or Second best mode—
Right sympathetic trunk, cervical (in the superior third of the neck, at the level C2-C3) and/or Left sympathetic trunk (Left upper cervical third part between C2-C3) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissuesand while the electro-stimulation-parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms;
Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
116. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Snoring, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right sympathetic trunk, cervical (in the superior third of the neck, at the level C2-C3) and/or Left sympathetic trunk (Left upper cervical third part between C2-C3) or Second best mode—
Spinal cord (at the level T10-T-12) while using the following sensors;
Arterial pressure meter, Heart rate meter. Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues and while the electro-stimulation 1 parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
117. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Chronic gastroenterocolitis, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or left vagus nerve (in the superior third of the neck, at the level C2-C3) or Second best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter Temperature gage, Angular shift sensor (for the limbs);
Local blood flow sensor. Sensor of electric activity of the organs, nervous centers. Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
118. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Chronic gastroenterocolitis, using one or more electrodes as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Right vagus nerve (in the superior third of the neck, at the level C2-C3) and/or left vagus nerve, left (in the superior third of the neck, at the level C2-C3) or Second best mode—
Right sympathetic trunk, thoracic (in the superior third, at the level T2-T4) and/or left sympathetic trunk, thoracic, left (in the superior third, at the level T7-T-11) while using the following sensors;
Arterial pressure meter, Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor. Sensor of electric activity of the organs, nervous centers Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues, Biosensor of sugar contents in the blood, and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ, Duration of current pulses;
0.1-0.8 Ms, Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
119. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Stammering, using one or more electrodes as detailed, wherein the electrodes are implanted in the following locations inside a patient'"'"'s body:
- Best mode—
Sinocarotid collector, right (over the bifurcation spot of the common carotid artery) and/or left sinocarotid collector, left (over the bifurcation spot of the common carotid artery) or Second best mode—
Right sympathetic trunk, cervical (in the superior third of the neck, at the level C2-C3) and/or Left sympathetic trunk (Left upper cervical third part between C2-C3) while using the following sensors;
Arterial pressure meter. Heart rate meter, Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues and while the electro-stimulation parameters are as follows;
Current frequency;
1-300 HZ. Duration of current pulses;
0.1-0.8 Ms,Amplitude of current pulses;
0.02-1 V.
- Best mode—
-
120. The method of treatment by electro-stimulator as detailed in claim 17 applied for treating Agranulocytosis, Anemia, Atrophy of he optic nerve:
- Skin atrophy, Sardiac achalasia, Coagulation disorders;
Buerger'"'"'s disease, Crohn'"'"'s disease, Pick'"'"'s disease, Raynaud'"'"'s disease, Vegetovascular dystony, Sudden cardiac arrest at sleep, Rectal prolapse, Flaccidly consolidating fractures, Hyperkeratosis;
Hyperostosis, Adrenal cortex hyperfunction, Hypoglycemia, Subcortical dementia, Multi-infarction dementia Involuntary movements, Dyskinesia of the biliferous tracts, Dysmenorrhea (genital diseases), Dolichosigmoid, Stammering, Impotence, Leucosis;
Migraine, Myodystrophy, Myopathy;
Male and female infertility, Narcolepsy, Bauhin'"'"'s valve failure, Neurodermite, Obliterating atherosclerosis of the limbs'"'"' vessels, Obliterating endarteritis of the lower limbs'"'"' vessels, Alopecia, Paralyses of different etiology, Paresis of the vocal cords, Progressing myodystrophy, Psoriasis. Rickets, Zollinger-Ellison syndrome, Commissural disease, Huntington'"'"'s chorea, Chronic duodenal ileus. Chronic and acute hyperthermia, Chronic gastroenterocolitis, Chronic cholecystitis and cholecystopancreatitis. Chronic cystitis. Chronic glomerulonephritis, Chronic obstructive bronchitis, Chronic osteomyelitis, Chronic pyelonephritis. Cirrhosis. Eczema. Pulmonary emphysema, Enuresis and/or Duodenal ulcer, using one or more electrode as detailed wherein the electrodes are implanted in the following locations inside a patient'"'"'s body;
Sinocarotid collector, right (over the bifurcation spot of the common carotid artery) And/or Sinocarotid collector, left (over the bifurcation spot of the common carotid artery) And/or Sympathetic trunk, thoracic, right (in the superior third, at the level T2-T4) And/or Sympathetic trunk, thoracic, left (in the superior third, at the level T7-T-11) And/or Vagus nerve, left (in the superior third of the neck, at the level C2-C3) And/or Vagus nerve, right (in the superior third of the neck, at the level C2-C3) And/or Sympathetic trunk, cervical, right (in the superior third of the neck, at the level C2-C3) And/or Left sympathetic trunk (Left upper cervical third part between C2-C3) And/or Spinal cord (at the level T10-T-12) And/or Nerve collector of the organ (Muscles) And/or Depressor nerve, right (over the aortic arch or in the middle third of the neck) And/or Depressor nerve, left (over the aortic arch or in the middle third of the neck) while using the following sensors. Arterial pressure meter, Heart rate meter. Respiration rate meter, Temperature gage, Angular shift sensor (for the limbs), Local blood flow sensor, Sensor of electric activity of the organs, nervous centers, Gastric juice acidity sensor, Murmur sensor (heart, lungs, intestine), while using the following bio-sensors;
Biosensor of oxygen contents in the tissues. Biosensor of sugar contents in the blood, Biosensor of hormone contents in the blood Biosensor of alcohol contents in the blood. Biosensor of narcotic substances contents in the blood, and while the electro-stimulation parameters are as follows;
Current;
frequency;
1-300 HZ Duration of current pulses-0.1-0.8 Ms. Amplitude of current pulses;
0.02-1 V.
- Skin atrophy, Sardiac achalasia, Coagulation disorders;
-
121. The medical treatment method according to claim 17 wherein, in order to increase the safety level of the implanted Stimulator (to prevent one patient from accidental using of non-implanted parts of the Electric Stimulator that belongs to another patient), each Electric Stimulator is assigned a data code (PIN code, similarly to cellular phones), to make sure the Electric Stimulator is used on an individual basis only, while due to this feature it also becomes possible to remotely (for example, via the Internet) replace the Electric Stimulator'"'"'s software, to monitor and to examine the patient'"'"'s condition from large distances.
-
122. The medical treatment method according to claim 17 wherein a PIN-card (like in cellular phones) is either inserted into the Electric Stimulator, or a relevant data code can be saved in the memory unit thereof.
-
123. The medical treatment method according to claim 17 wherein the codes will also be used for manufacturing accountability purposes which is important in order to prevent other companies from faking the device.
-
124. The medical treatment method according to claim 17 wherein upon occurrence of abnormal functioning of the body'"'"'s systems, organs, tissues, either as a result of the Electric Stimulator'"'"'s operation or regardless thereof, endangering the patient'"'"'s health, the Electric Stimulator'"'"'s indicating device informs both the patient and medical personnel of such occurrence via the internal and/or external radio-frequency communication units, being specific about a certain side effect that has developed, after which the Electric Stimulator is automatically deactivated, in case this said side effect has developed as a response to any program of the Electric Stimulator;
- while such Electric Stimulator'"'"'s programs identified during the Stimulator'"'"'s adjustment using the external display, are either removed from the device, or they are replaced with the programs that do not cause side effects.
-
125. The medical treatment method according to claim 17 wherein to increase the Electric Stimulator'"'"'s reliability and safety for the patient, the device has an option, in case of its breakdown, allowing the Electric Stimulator to directly transmit stimulating pulses to the electrode (electrodes) from the external radio-frequency communication unit, via the internal radio-frequency communication unit, for which purpose the latter is connected to the electrode(s) through the backup communication unit.
-
126. The medical treatment method according to claim 17 wherein its internal radio-frequency communication unit is made selectively sensitive to only those signals sent by the external units and addressed thereto, that have an identification information code belonging to a specific Electric Stimulator (PIN-type code), while the signals which do not contain the above-mentioned code do not affect the Electric Stimulator'"'"'s operation and cannot control it.
-
127. The medical treatment method according to claim 17 wherein its internal radio-frequency communication unit is made selectively sensitive to only those signals sent by the external units and addressed thereto, to enable the information code enables security preventing any unauthorized access to the Electric Stimulator.
-
128. The medical treatment method according to claim 17 applied for Correction of Functional Activity of the Body'"'"'s Systems, and or Organs, and/or Tissues in a healthy person that has the following distinct feature:
- the optimal mode of impacting the body with the Electric Stimulator (electric current parameters, duration of electric stimulation sessions, etc.) are selected and controlled automatically, and/or by the doctor, and/or by the patient in a real time frame in accordance with the program algorithms input the Electric Stimulator, and subject to an analysis conducted by means of implanted or non-implanted sensor(s) and/or biosensor(s) of one or a set of homeostatic properties of the body;
contents and concentration of substances, gases in the body'"'"'s tissues and liquid media, and values of electric, mechanical and/or acoustic activity of the organs and tissues;
in order to obtain the maximal correcting effect (of stimulation or inhibition), one or several systems, and/or tissues, and/or organs of the body are simultaneously subjected to the electric stimulation through individual channels, electrodes, program algorithms or through one, common program and algorithms.
- the optimal mode of impacting the body with the Electric Stimulator (electric current parameters, duration of electric stimulation sessions, etc.) are selected and controlled automatically, and/or by the doctor, and/or by the patient in a real time frame in accordance with the program algorithms input the Electric Stimulator, and subject to an analysis conducted by means of implanted or non-implanted sensor(s) and/or biosensor(s) of one or a set of homeostatic properties of the body;
-
129. The medical treatment method according to claim 17 applied for a healthy person wherein a principle of long-term (“
- calendar”
) programming is used in the Electric Stimulator, and this includes application of the following three types of programs;
First-Type Programs—
programming of the Electric Stimulator for the period of 1-30 days, Second-Type Programs—
programming of the Electric Stimulator for the period of 1 up to 12 months, in accordance with the signals sent by the sensors and biosensors, or irregardless thereof, Third-Type Programs—
programming of the Electric Stimulator for the period of more than 12 months (years).
- calendar”
-
130. The medical treatment method according to claim 17 applied for a healthy person that have the following distinct features. Electric Stimulator and the electrode(s) thereof can be implanted into different parts of the body, including tissues, organs and/or vessels, while the Electric Stimulator'"'"'s shell is implanted either into the subcutaneous fat of the right or left subclavian areas, or into the subcutaneous fat of the anterior abdominal wall, in the left hypochondriumn or into the lumbar area, either form the right or left.
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131. The medical treatment method according to claim 17 applied for settings of the implanted Stimulator, control and analysis thereof, as well as control and analysis of functional activity of the body'"'"'s systems, organs and tissues impacted with the Electric Stimulator, may be carried out without the external non-implanted display and it can be based or the existing methods and equipment widely used and radio electronics.
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148. The medical treatment method according to claim 17, wherein stimulating and/or inhibiting the functional activity of the nervous structure of the sympathetic nervous system, the parasympathetic system or the sympathetic nervous system and parasympathetic system and hypoglossal (sinocarotid collector of the Vegetative Nervous System-SCVNS), the central nervous system, and/or neurons of the organ and/or cutaneous nerves and/or depressor nerves.
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149. The medical treatment method according to claim 17, wherein a nervous band or group is formed, comprising all, or the majority of, the nerve branches innervating the carotid glome (glomus caroticum).
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150. The medical treatment method according to claim 17, using Contacts, or indirect body measurements and using adaptive techniques for measuring body variables.
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18. The medical treatment method according to claim 17 which, for stimulating and/or inhibiting the functional activity of the body'"'"'s systems and separate organs and tissues, uses pulse currents of parameters as detailed in the present disclosure.
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141. A medical instrument implanted in a patient'"'"'s body, comprising sensor means for measuring variables inside the body, processor means for processing the signals and monitoring the patient'"'"'s health, and transmitter means for transmitting results of the monitoring to a receiver external to the patient'"'"'s body.
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142. The medical instrument according to claim 202, further including recording means for storing results of the patient monitoring, and wherein the processor compares the monitoring results with stored previous results and issues a warning or alarm if a undesirable change is detected.
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143. The medical instrument according to claim 202, further including receiver means for receiving an external request for information and means in the processor for checking the validity of the request, and means for transmitting the monitoring results to an external receiver upon receiving a legitimate request.
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144. The medical instrument according to claim 202, wherein the external receiver further including means for connecting to electronic equipment and/or Internet, for the processing and/or transfer of the monitoring results.
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145. The medical instrument according to claim 205, wherein the processor means is programmed to perform a continuous monitoring of the patient and for issuing an alarm in real time if an undesirable change in the sensor'"'"'s reading is detected.
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146. The medical instrument according to claim 205, wherein the processor means is programmed to issue a report of the internal health state of the patient upon receiving a predefined request.
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147. The medical instrument according to claim 205, wherein the processor means is programmed to perform a test at predefined time periods such as once per year or once per month, and to transmit the results of the test to an external receiver.
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151. The medical treatment method according to claim 211 wherein during an initial stage after the implantation of the system;
- the sensors and biosensors are used to measure the body variables, together with the contacts, and wherein the variables from contacts are then compared in the Chip with the readouts from the sensors and biosensors.
Specification
- Resources
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Current AssigneeSe Karashurov
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Original AssigneeSe Karashurov
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InventorsS.E., Karashurov
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Application NumberUS11/220,729Publication NumberTime in Patent OfficeDaysField of SearchUS Class Current607/2CPC Class CodesA61N 1/205 for promoting a biological ...A61N 1/326 for promoting growth of cel...A61N 1/36007 of urogenital or gastrointe...A61N 1/3601 of respiratory organsA61N 1/36082 Cognitive or psychiatric ap...A61N 1/36089 Addiction or withdrawal fro...A61N 1/36114 Cardiac control, e.g. by va...A61N 1/36117 for treating hypertensionA61N 1/37205 Microstimulators, e.g. impl...