Method of optimizing data collection and therapy delivery based on respiration

• US 20070156193A1
• Filed: 12/30/2005
• Published: 07/05/2007
• Est. Priority Date: 12/30/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Cho, Yong, Burnes, John
• Granted Patent: US 7,623,917 B2
• Time in Patent Office: Days
• US Class Current: 607/23
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

A method and system for improving or optimizing the collection of data from and the delivery of therapy to a patient by an implantable medical device (IMD) is disclosed which uses information about the patient'"'"'s respiratory cycle.

Claims

1. A computer-readable medium programmed with instructions for performing a method of optimizing therapy delivery from an implantable medical device (IMD), the medium comprising instructions for causing a programmable processor to:

monitor respiratory cycles of a patient, including determining when an inspiration phase is occurring and when an expiration phase is occurring;

set therapy parameters to a first set of therapy parameters during the inspiration phase; and

set therapy parameters to a second set of therapy parameters different from the first set during the expiration phase.

2. A medium according to claim 1 further comprising instruction to determine the inspiration and expiration phases of the respiratory cycle by low-pass filtering a hemodynamic pressure signal of the patient.

3. A medium according to claim 2 wherein the hemodynamic pressure parameter is right ventricular pressure.

4. A medium according to claim 1 wherein the first and second sets of therapy parameters include cardiac pacing parameters.

5. A medium according to claim 4 wherein the cardiac pacing parameters include at least an interventricular paced timing delay, comprising a time interval from the occurrence of a depolarization event in one ventricular chamber to the programmed delivery of a pacing stimulus in the other ventricular chamber.

6. A medium according to claim 5 wherein the interventricular paced timing delay of the first set of therapy parameters is different from the interventricular timing delay of the second set of therapy parameters.

7. A medium according to claim 6 wherein the interventricular timing delay of the first set of therapy parameters is greater than the interventricular timing delay of the second set of therapy parameters.

8. A medium according to claim 4 wherein the cardiac pacing parameters include at least an atrio-ventricular (AV) delay.

9. A computer-readable medium programmed with instructions for performing a method of collecting hemodynamic data in an implantable medical device, the medium comprising instructions for causing a programmable processor to:

monitor respiratory cycles of a patient, including determining when an inspiration phase is occurring and when an expiration phase is occurring;

identify at least one timing reference point of a respiratory cycle; and

collect a set of hemodynamic data from the patient at intervals based on the at least one timing reference point of a respiratory cycle such that all data in the set were obtained during approximately the same portion of the respiratory cycle.

10. A medium according to claim 9 wherein the at least one timing reference point of a respiratory cycle includes a relative peak value that occurs during the respiratory cycle.

11. A medium according to claim 9 further comprising instructions to sample the hemodynamic data at most once per respiratory cycle to collect the set of hemodynamic data.

12. A medium according to claim 11 further comprising instructions to vary the number of respiratory cycles between successive hemodynamic data samples.

13. A medium according to claim 12 further comprising instructions to vary the number of respiratory cycles between successive hemodynamic data samples in response to changes in respiration rate.

14. A medium according to claim 9 further comprising instructions to collect multiple sets of hemodynamic data using multiple timing reference points.

15. A medium according to claim 9 further comprising instructions to collect multiple sets of hemodynamic data using a single timing reference point and at least one reference offset.

16. A medical device system comprising:

means for monitoring respiratory cycles of a patient; and

means for delivering therapy parameters that vary as a function of the phase of the patient'"'"'s respiratory cycle.

17. A system according to claim 16 further comprising:

means for determining when an inspiration phase is occurring and when an expiration phase is occurring;

means for delivering a first set of therapy parameters during the inspiration phase; and

means for delivering a second set of therapy parameters different from the first set during expiration phase.

18. A system according to claim 17 wherein the first and second set of therapy parameters includes cardiac pacing parameters including at least an interventricular paced timing delay (V-V delay), the V-V delay comprising a time interval from the occurrence of a depolarization event in one ventricular chamber to the programmed delivery of a pacing stimulus in the other ventricular chamber.

19. A system according to claim 16 further comprising means for delivering therapy parameters that vary substantially linearly as a function of the phase of the patient'"'"'s respiratory cycle.

20. A system according to claim 16 further comprising means for delivering therapy parameters that vary by different amounts between respiratory cycles.