ULTRASOUND SYNCHRONY MEASUREMENT
First Claim
1. A method for detecting the arrival of an applied pressure wave at an internal target site in a subject, said method comprising:
- (a) applying a pressure wave to said subject; and
(b) detecting a change in impedance between two electrodes stably associated with said target site to detect arrival of said pressure wave at said target site.
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Accused Products
Abstract
Methods for evaluating tissue motion of a tissue location, e.g., a cardiac location, are provided. Aspects of the methods include applying a pressure wave, e.g., ultrasound, to a subject and detecting a change in impedance between two electrodes stably associated with a target site to detect arrival of the pressure wave at said target site and thereby evaluate movement of the target site. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
69 Citations
25 Claims
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1. A method for detecting the arrival of an applied pressure wave at an internal target site in a subject, said method comprising:
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(a) applying a pressure wave to said subject; and
(b) detecting a change in impedance between two electrodes stably associated with said target site to detect arrival of said pressure wave at said target site. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20-23. -23. (canceled)
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24. A system for detecting the arrival of a pressure wave at an internal target site, said system comprising:
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(a) a pressure wave transmitter;
(b) a sensing elements stably associated with said target site, wherein said sensing element comprises two spaced apart electrodes; and
(c) a signal processing element configured to evaluate data obtained from said sensing element to detect the arrival of a pressure wave at said target location.
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25-34. -34. (canceled)
Specification