Computer-aided detection system utilizing temporal analysis as a precursor to spatial analysis
First Claim
1. A method for computer-aided detection in a four-dimensional series of medical images, the method comprising the following steps:
- (a) accessing a series of three dimensional medical images of a region of interest over a period of time, at least one set in the series being taken before administration of a contrast agent and a plurality of sets taken after the administration of a contrast agent to produce a four dimensional image;
(b) performing a temporal analysis to characterize each voxel in the four dimensional image;
(c) performing a spatial analysis influenced by the temporal characterizations to segment the voxels into tissue types.
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Abstract
A computer-aided detection system for evaluating tissue based on a series of timed images acquired both before and after a contrast agent is administered performs a temporal analysis of the tissue and then a spatial analysis in which the tissue is categorized. After the temporal and spatial analysis is performed, the results can be displayed. The displayed results can include both tissue characterization results, underlying curves used to determine the characterization, and confidence data regarding how good the characterization is expected to be. The confidence data can be provided, for example, by using variations in color schemes, displaying numerical confidence levels, or providing graphical features such as piecewise linear models.
54 Citations
20 Claims
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1. A method for computer-aided detection in a four-dimensional series of medical images, the method comprising the following steps:
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(a) accessing a series of three dimensional medical images of a region of interest over a period of time, at least one set in the series being taken before administration of a contrast agent and a plurality of sets taken after the administration of a contrast agent to produce a four dimensional image;
(b) performing a temporal analysis to characterize each voxel in the four dimensional image;
(c) performing a spatial analysis influenced by the temporal characterizations to segment the voxels into tissue types. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method for computer-aided detection in a four-dimensional series of medical images, the method comprising the following steps:
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(a) accessing a series of three dimensional medical images of a region of interest over a period of time, at least one set in the series being taken before administration of a contrast agent and a plurality of sets taken after the administration of a contrast agent to produce a four dimensional image;
(b) selecting a first scale space for processing the images and, for each of the images in the series;
(c) performing a temporal analysis to characterize each voxel in the four dimensional image (d) performing a spatial analysis based on the temporal characterization to segment the voxels into at least one tissue type;
(e) selecting a new scale space and repeating steps (c-d) over a range of scale spaces. - View Dependent Claims (16, 17, 18, 19)
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20. A computer program for computer-aided detection in a four-dimensional series of medical images comprising:
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at least one machine readable medium;
computer code stored on the at least one machine readable medium including code for the following steps;
(a) accessing a series of three dimensional medical images of a region of interest over a period of time, at least one set in the series being taken before administration of a contrast agent and a plurality of sets taken after the administration of a contrast agent to produce a four dimensional image;
(b) performing a temporal analysis to characterize each voxel in the four dimensional image (c) performing a spatial analysis based on the temporal characterization and spatial attributes in the image to segment the voxels into tissue types and to identify voxels of interest.
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Specification