Extracellular matrix based gastroesophageal junction reinforcement device
First Claim
1. A device comprising one or more layers of extracellular matrix tissue and comprising:
- a) a tubular esophageal portion having essentially a constant diameter; and
b) a tubular gastric portion attached to the esophageal portion at a junction having a diameter that increases from the junction to a distal tip of the gastric portion.
2 Assignments
0 Petitions
Accused Products
Abstract
Provided are medical devices for implantation in patients having suffered the loss of or damage to at least part of their esophagus. The medical device connects the esophagus or remaining part thereof with the stomach to form a gastro-esophageal junction that promotes healing and encourages new host tissue growth while distributing the load and decreasing tension at the anastomotic site. The medical device comprises extracellular matrix shaped into a conformation that more closely approximates the geometry of the native gastro-esophageal junction than does direct attachment of the stomach to the shortened esophagus. Molds useful in manufacturing the medical device and methods of use of the device are also described herein.
60 Citations
50 Claims
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1. A device comprising one or more layers of extracellular matrix tissue and comprising:
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a) a tubular esophageal portion having essentially a constant diameter; and
b) a tubular gastric portion attached to the esophageal portion at a junction having a diameter that increases from the junction to a distal tip of the gastric portion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A mold for molding extracellular matrix tissue, comprising:
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a) a tubular esophageal portion having essentially a constant diameter; and
b) a tubular gastric portion attached to the esophageal portion at a junction having a diameter that increases from the junction to a distal tip of the gastric portion. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30)
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31. A method of reinforcing an anastomotic site in a patient comprising implanting a device between a portion of the patient'"'"'s esophagus and stomach, the device comprising one or more layers of extracellular matrix tissue and comprising:
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a) a tubular esophageal portion having essentially a constant diameter; and
b) a tubular gastric portion attached to the esophageal portion at a junction having a diameter that increases from the junction to a distal tip of the gastric portion. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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Specification