Nutritional supplement containing long-chain polyunsaturated fatty acids

• US 20070166411A1
• Filed: 12/11/2006
• Published: 07/19/2007
• Est. Priority Date: 12/16/2005
• Status: Abandoned Application

• Current Assignee: Mead Johnson Nutrition Company (Reckitt Benckiser Group PLC)
• Original Assignee: Bristol-Myers Squibb Company
• Inventors: Anthony, Joshua, Hossen, Monjur, Schade, Deborah, Peterson, Catherine, Samuel, Priscilla, Sims, Kevin
• Application Number:
  US11/637,484
• Publication Number:
  US 20070166411A1
• Time in Patent Office: Days
• US Class Current: 424/750
• CPC Class Codes: A23L 33/12 Fatty acids or derivatives thereof
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/30 Foods, ingredients or supplements having a functional effect on health
• CPC Class Codes: A23V 2250/1868 Docosahexaenoic acid
• CPC Class Codes: A23V 2250/1882 Polyunsaturated fatty acids
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/202 having three or more double bonds, e.g. linolenic eicosanoids, e.g. leukotrienes A61K31/557

Abstract

The present invention relates to a nutritional supplement for administration to children. The supplement comprises a protein component, a carbohydrate component, and a fat or lipid component which further comprises a source of DHA. The supplement has an ω-6:ω3 fatty acid ratio of about 6:1 or less. The present invention also relates to a method of providing nutrition to a pediatric subject comprising administering to the subject a nutritional supplement comprising a protein component; a carbohydrate component; and a fat or lipid component, which further comprises a source of DHA, wherein the composition has an ω-6:ω-3 fatty acid ratio of about 6:1 or less.

Claims

1. A nutritional supplement for administration to children, the nutritional supplement comprising:

a protein component;

a carbohydrate component; and

a lipid component comprising a source of DHA, wherein the supplement has an ω

-6;

ω

-3 fatty acid ratio of about 6;

1 or less.

2. The nutritional supplement according to claim 1, wherein the nutritional supplement has an ω

-6;

ω

-3 fatty acid ratio of about 3;

1 or less.

3. The nutritional supplement according to claim 1, wherein the nutritional supplement has an ω

-6;

ω

-3 fatty acid ratio of about 1;

1.

4. The nutritional supplement according to claim 1, wherein the supplement is nutritionally complete.

5. The nutritional supplement according to claim 1, wherein the supplement is a liquid.

6. The nutritional supplement according to claim 1, wherein the carbohydrate component comprises a mixture of maltodextrin and sucrose.

7. The nutritional supplement according to claim 1, wherein the protein component comprises milk protein concentrate.

8. The nutritional supplement according to claim 1, wherein the lipid component comprises a mixture of at least one source of linoleic acid and at least one source of α

-linolenic acid.

9. The nutritional supplement according to claim 1, wherein the lipid component comprises a mixture of canola oil, soybean oil, high oleic sunflower oil, medium chain triglyceride (MCT) oil, and corn oil.

10. The nutritional supplement according to claim 1, wherein the source of DHA comprises single-celled organisms.

11. The nutritional supplement according to claim 1, wherein the nutritional supplement contains DHA in an amount of between about 0.1 mg/100 kcal of supplement and about 1 g/100 kcal of supplement.

12. The nutritional supplement according to claim 1, wherein the nutritional supplement contains DHA in an amount of between about 5 mg/100 kcal of supplement and about 50 mg/100 kcal of supplement.

13. The nutritional supplement according to claim 1, wherein the nutritional supplement contains DHA in an amount of between about 7.5 mg/100 kcal of supplement and about 25 mg/100 kcal of supplement.

14. The nutritional supplement according to claim 1, wherein the nutritional supplement contains DHA in an amount of about 17 mg/100 kcal of supplement.

15. The nutritional supplement according to claim 1, further comprising human or animal milk.

16. The nutritional supplement according to claim 1, further comprising at least one prebiotic.

18. The nutritional supplement according to claim 1, wherein the supplement contains about 250 kcal per serving.

19. The nutritional supplement according to claim 1, wherein the supplement contains between about 160 and 180 kcal per serving.

20. The nutritional supplement according to claim 20, wherein the supplement does not contain artificial sweeteners.

21. The nutritional supplement according to claim 20, wherein the sweeteners in the supplement consist of sucrose and fructose.

22. A nutritional supplement for administration to children, the nutritional supplement comprising:

a protein component;

a carbohydrate component; and

a lipid component comprising, in % w/w of the total lipid component;

between about 10% and about 50% canola oil;

between about 5% and about 40% soy oil;

between about 5% and about 40% high oleic sunflower oil;

between about 5% and about 40% medium chain triglyceride oil;

between about 1% and about 20% corn oil; and

between about 0.1% and about 10% of a source of DHA.

23. The nutritional supplement according to claim 23, wherein the lipid component comprises, in % w/w of the total lipid component:

29.3% canola oil;

20.7% soy oil;

20.5% high oleic sunflower oil;

19.8% medium chain triglyceride oil;

8.8% corn oil; and

0.9% of a source of DHA.

17. The nutritional supplement according to claim 24, wherein the prebiotic is selected from the group consisting of lactulose, galacto-oligosaccharide, fructo-oligosaccharide, isomalto-oligosaccharide, soybean oligosaccharides, lactosucrose, xylo-oligosacchairde, inulin, polydextrose and gentio-oligosaccharides.

24. The nutritional supplement according to claim 23, wherein the supplement has an ω

-6;

ω

-3 fatty acid ratio of about 6;

1 or less.

25. A liquid pediatric nutritional supplement comprising:

a protein component that comprises milk protein concentrate;

a carbohydrate component that comprises a mixture of maltodextrin and sucrose;

a vitamin and mineral component; and

a lipid component comprising, in % w/w of the total lipid component, about;

29.3% canola oil;

20.7% soy oil;

20.5% high oleic sunflower oil;

19.8% medium chain triglyceride oil;

8.8% corn oil; and

0.9% of a source of DHA,

wherein the supplement is nutritionally complete and has an ω

-6;

ω

-3 fatty acid ratio of about 6;

1 or less.

26. A method of providing nutrition to a pediatric subject comprising administering to the subject a nutritional supplement comprising a protein component, a carbohydrate component, and a lipid component that comprises a source of DHA, wherein the nutritional supplement has an ω

-6;

ω

-3 fatty acid ratio of about 6;

1 or less.

27. The method according to claim 27, wherein the subject is between the age of about 9 months and about 13 years.

28. The method according to claim 27, wherein the subject is between the age of about 1 year and 10 years.

29. The method according to claim 34, wherein the subject suffers from chronic illness, injury, trauma, failure to thrive, slow growth, undernourishment, poor immune function, poor cardiovascular function, weak bone strength, poor mental health development, recovery from surgery or illness, poor appetite, anorexia, bulimia, impaired ability to digest other sources of nutrition, and mixtures thereof.

30. The method according to claim 34, wherein the supplement is administered to the subject in combination with human or animal milk.