Materials, devices and methods for treating multiple spinal regions including the interbody region

• US 20070168038A1
• Filed: 01/13/2006
• Published: 07/19/2007
• Est. Priority Date: 01/13/2006
• Status: Abandoned Application

• Current Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Original Assignee: SDGI Holdings Incorporated (Medtronic Plc)
• Inventors: Trieu, Hai
• Application Number:
  US11/331,701
• Publication Number:
  US 20070168038A1
• Time in Patent Office: Days
• US Class Current: 623/17.150
• CPC Class Codes: A61B 17/70 Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
• CPC Class Codes: A61B 17/7059 Cortical plates A61B17/7007, A61B17/7058 take precedence
• CPC Class Codes: A61B 17/8802 Equipment for handling bone cement or other fluid fillers
• CPC Class Codes: A61F 2/4425 made of articulated components
• CPC Class Codes: A61F 2002/30578 having apertures, e.g. for receiving fixation screws
• CPC Class Codes: A61F 2002/30649 Ball-and-socket joints
• CPC Class Codes: A61F 2002/30884 Fins or wings, e.g. longitudinal wings for preventing rotation within the bone cavity
• CPC Class Codes: A61F 2002/444 for replacing the nucleus pulposus

Abstract

A method of treating a spinal condition includes placing disc replacement material in an intervertebral disc, thereby altering a loading characteristic of an adjacent vertebrae, and supporting the adjacent vertebrae by applying a bone filling material to either a superior or inferior vertebral body adjacent to the intervertebral disc. The disc placement material may also be configured to augment the intervertebral disc.

Claims

1. A method of treating a spinal condition comprising:

placing disc replacement material in an intervertebral disc, thereby altering a loading characteristic of an adjacent vertebrae; and

supporting the adjacent vertebrae by applying a bone filling material to either a superior or inferior vertebral body adjacent to the intervertebral disc.

2. The method of claim 1 wherein the disc placement material is configured to augment the intervertebral disc.

3. The method of claim 1 wherein the disc replacement material is a fusion device.

4. The method of claim 3 wherein the fusion device is a cage.

5. The method of claim 3 wherein the fusion device is a spacer.

6. The method of claim 1 wherein the disc replacement material is a motion preservation device comprising a curved protrusion adapted to articulate with a curved recess.

7. The method of claim 1 wherein the disc replacement material is a motion preservation device comprising a central component adapted to articulate between a pair of endplate components.

8. The method of claim 1 wherein the disc replacement material comprises an elastomeric material adapted to occupy an area within a natural annulus.

9. The method of claim 1 wherein the step of placing replacement material in the intervertebral disc comprises injecting material into a natural nucleus of the intervertebral disc.

10. The method of claim 8 wherein the injected material is curable in situ.

11. The method of claim 1 wherein applying a bone filling material further comprises expanding a void creation device within the superior or inferior vertebral body to create a void and filling at least a portion of the created void with a hardenable material.

12. The method of claim 10 wherein the void creation device is an inflatable device.

13. The method of claim 1 wherein the bone filling material includes a material selected from a group consisting of:

polymethylmethacrylate (PMMA), calcium phosphate, hyrdroxyapatite-tricalcium phosphate (HA-TCP) compounds, bioactive glasses, polymerizable matrix comprises a bisphenol-A dimethacrylate, and thermoset cortical bone void filler.

14. The method of claim 1 wherein the bone filling material includes a material selected from a group consisting of:

demineralized bone matrix, collagen, gelatin, polysaccharide, hyaluronic acid, keratin, albumin, fibrin, and combinations thereof.

15. The method of claim 1 wherein the bone filling material includes inorganic particles selected from a group consisting of:

hydroxyapatite, fluorapatite, oxyapatite, Wollastonite, anorthite, calcium fluoride, agrellite, devitrite, canasite, phlogopite, monetite, brushite, octocalcium phosphate, Whitlockite, tetracalcium phosphate, cordierite, Berlinite, and mixtures thereof.

16. The method of claim 1 wherein the bone filling material comprises growth factors, hormones, or cells

17. The method of claim 15 wherein the bone growth factor includes an element selected from a group consisting of:

BMP, TGF, and platelet-derived material.

18. The method of claim 1 wherein the bone filling material comprises mysenchymal stem cells.

19. A method of treating a spinal condition comprising:

placing an augmentation material in an intervertebral disc, thereby altering a characteristic of a first vertebrae; and

supporting the adjacent vertebrae by replacing at least a portion of a second, adjacent vertebral with an artificial vertebral body.

20. The method of claim 19 wherein the augmentation material includes a nucleus replacement implant.

21. A method of treating a spinal condition comprising:

placing a disc replacement system in an intervertebral disc space between a pair of vertebrae; and

supporting the disc replacement system to maintain disc height by connecting an anterior system between the pair of vertebrae.

22. The method of claim 21 wherein the anterior system comprises a PEEK plate.

23. The method of claim 21 wherein the anterior system comprises a bioresorbable plate.

24. The method of claim 21 wherein the anterior system comprises a woven or braided structure.

25. The method of claim 21 wherein the anterior system comprises an elastic tension band.

26. A method of treating a spinal condition comprising:

placing a disc replacement system in an intervertebral disc space;

supporting the disc replacement system to maintain disc height by connecting an anterior system between a pair of vertebrae; and

reinforcing at least one of the pair of vertebrae to support the disc replacement system by treating at least one of the pair of vertebrae with a vertebral body treatment material.

27. The method of claim 26 further comprising:

reinforcing an endplate of at least one of the pair of vertebrae to support the disc replacement system by treating the end plate with an endplate treatment material.

28. The method of claim 26 wherein the vertebral body treatment material comprises polymethylmethacrylate.

29. The method of claim 26 wherein the vertebral body treatment material includes a material selected from a group consisting of:

hydroxyapatite, tricalcium phosphate, and injectable collagen.

30. The method of claim 27 wherein the endplate treatment material comprises BMP.

31. The method of claim 27 wherein the endplate treatment material comprises polymethylmethacrylate.

32. The method of claim 26 wherein the anterior system includes an element selected from a group consisting of:

a PEEK plate, a bioresorbable plate, a woven or braided structure, and an elastic tension band.

33. A method of treating a spinal condition comprising:

placing a disc replacement system in an intervertebral disc space between a pair of vertebrae; and

reinforcing an endplate of at least one of the pair of vertebrae to support the disc replacement system by treating the endplate with an endplate treatment material.

34. The method of claim 33 wherein the disc replacement system is a motion preservation system.

35. The method of claim 34 wherein the motion preservation system comprises a single pair of articulating surfaces.

36. The method of claim 34 wherein the motion preservation system comprises two pairs of articulating surfaces.

37. The method of claim 33 wherein the endplate treatment material comprises hydroxyapatite.

38. The method of claim 33 wherein the endplate treatment material comprises tricalcium phosphate.

39. The method of claim 33 wherein the endplate treatment material comprises a bone growth factor.

40. The method of claim 33 wherein the endplate treatment material comprises collagen.

41. A method of treating a spinal condition comprising:

placing a disc replacement system in an intervertebral disc space between a pair of vertebrae; and

reinforcing an endplate of at least one of the pair of vertebrae to support the disc replacement system by treating the endplate with an endplate treatment material.

42. The method of claim 41 further comprising:

reinforcing at least one of the pair of vertebrae to support the disc replacement system by treating at least one of the pair of vertebrae with a vertebral body treatment material; and

43. The method of claim 41 wherein the endplate treatment material includes a material selected from a group consisting of:

polymethylmethacrylate, DBM, platelet-derived growth factors, and calcium sulfate.

44. The method of claim 42 wherein the vertebral body treatment material includes a material selected from a group consisting of:

polymethylmethacrylate, DBM, platelet-derived growth factors, and calcium sulfate.

45. The method of claim 41 wherein the disc replacement system includes an element from a group consisting of:

an elastomeric material, a mechanical spring element, an elastomeric nucleus replacement implant, and an injectable polymer.

46. The method of claim 41 wherein the disc replacement system comprises an intervertebral portion and a bridge portion extending posteriorly from the intervertebral portion.