Calibration of Sensors or Measuring Systems
First Claim
1. A method for calibrating continuous sensors or automatic measuring systems in the interstitium, comprising the steps of setting a gradient of a measuring curve and a standard offset prior to use, and adapting the offset during use by a one-point calibration with the aid of a reference measurement.
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Accused Products
Abstract
A method for adjusting a sensor, continuous sensor or automatic measuring system in an interstitium including the steps of adjusting the steepness of a measuring curve and a standard offset (standard axis intercept) prior to the use of the sensor, continuous sensor or measuring system, and adapting the offset by a point calibration by using a reference measure or value during the use. The present invention encompasses sensors, continuous sensors or automatic measuring systems calibrated or adjusted in accordance with the method, and in some embodiments, the offset adjusted prior to use is rectified according to the difference between a value determined by the sensor, continuous sensor or measuring system taking into account the standard steepness and the reference value.
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Citations
30 Claims
- 1. A method for calibrating continuous sensors or automatic measuring systems in the interstitium, comprising the steps of setting a gradient of a measuring curve and a standard offset prior to use, and adapting the offset during use by a one-point calibration with the aid of a reference measurement.
- 8. A method for calibrating continuously measuring sensors or automatic measuring systems for glucose in the interstitium, wherein, to compensate a physiologically conditioned deviation in a glucose content between a location of a reference measurement and a location of the sensor measurement, a trend signal of a glucose value is used as additional information in a calibration of the measuring system or sensor.
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12. A measuring system or sensor for carrying out a calibration method comprising the steps of setting a gradient of a measuring curve and a standard offset prior to use, and adapting the offset during use by a one-point calibration with the aid of a reference measurement.
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13. A measuring system or sensor for carrying out a calibration method, wherein, to compensate a physiologically conditioned deviation in a glucose content between a location of a reference measurement and a location of a sensor measurement, a trend signal of a glucose value is used as additional information in the calibration of the measuring system or sensor.
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14. A measuring system for determining a value of a biochemical parameter, the measuring system comprising:
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a) a measuring sensor (2, Rm, Rref), having a known gradient and a known offset, for recording a measured value in vivo in a temporally sequential or continuous fashion, and outputting measuring sensor values (P1, P2), the measured values of the measured variable or formed from the measured values, and b) a data acquisition device that receives the measuring sensor values and at least one reference value and forms characteristic values of the parameter from the measuring sensor values, wherein c) for the purpose of an automatic self-calibration of the measuring system, the data acquisition device compares one of the characteristic values with the at least one reference value or a value calculated therefrom, and the offset of the measuring sensor is adjusted in accordance with the result of the comparison by a one-point calibration. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification