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Enzymatic nucleic acid synthesis: compositions including pyrophosphorolysis inhibitors

  • US 20070172819A1
  • Filed: 12/29/2006
  • Published: 07/26/2007
  • Est. Priority Date: 12/01/2000
  • Status: Abandoned Application
First Claim
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1. A composition comprising a modified nucleotide including a molecular and/or atomic tag, a nucleotide polymerizing agent, a primer, a template and a pyrophosphorolysis inhibitor, where the modified nucleotide alters base incorporation fidelity of the nucleotide polymerizing agent relative to a base incorporation fidelity of the agent in the absence of the modified nucleotide and where the pryophosphorolysis inhibitor reduces pryophosphorolysis.

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