Membranes for an analyte sensor
First Claim
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1. An electrochemical analyte sensor configured for implantation in vivo and for measuring an analyte concentration in a host, the sensor comprising:
- at least one electroactive surface; and
a membrane system disposed on the electroactive surface, wherein the membrane system comprises an electrode domain, wherein the electrode domain is adjacent to the electroactive surface, and wherein the sensor is configured to break in, in vivo, in less than about 2 hours.
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Abstract
The present invention relates generally to devices for measuring an analyte in a host. More particularly, the present invention relates to devices for measurement of glucose in a host that incorporate a hydrophilic electrode domain and/or a cellulosic-based interference domain.
443 Citations
39 Claims
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1. An electrochemical analyte sensor configured for implantation in vivo and for measuring an analyte concentration in a host, the sensor comprising:
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at least one electroactive surface; and
a membrane system disposed on the electroactive surface, wherein the membrane system comprises an electrode domain, wherein the electrode domain is adjacent to the electroactive surface, and wherein the sensor is configured to break in, in vivo, in less than about 2 hours. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. An electrochemical analyte sensor configured for implantation in vivo and for measuring an analyte concentration in a host, the sensor comprising:
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at least one electroactive surface; and
a membrane system disposed on the electroactive surface, wherein the membrane system comprises a uni-component hydrophilic domain, wherein the hydrophilic domain is adjacent to the electroactive surface. - View Dependent Claims (24, 25, 26, 27, 28, 29)
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30. A method of using an analyte sensor configured for in vivo implantation in a host, comprising:
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implanting an analyte sensor in a host;
allowing the sensor to break-in in vivo; and
measuring a signal representative of a concentration of an analyte in the host, wherein the step of measuring is capable of being performed with substantial accuracy less than about 2 hours after the step of implanting. - View Dependent Claims (31, 32, 33, 34, 35, 36, 37, 38, 39)
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Specification