Drug reservoir stent
First Claim
1. A drug delivery stent for implanting in a bodily passageway, lumen or duct, comprising:
- a radially expandable stent body formed of one or more metallic or polymer strut filaments, each strut filament having outer, inner, side and end surfaces;
a drug reservoir composed of a therapeutic drug being carried on one or more surfaces of each strut filament; and
a durable shell coating covering said drug reservoir and having at least one perforation extending through the coating.
1 Assignment
0 Petitions
Accused Products
Abstract
Drug reservoir stents and methods of making and using the same are described. Such drug reservoir stents are prepared by applying a sacrificial material to one or more surfaces of the strut filaments of a drug delivery stent and applying a durable coating material to the surface of the sacrificial material to create a durable shell. A drug reservoir is created between the surface(s) of the strut filament and the durable shell by creating at least one perforation in the durable shell and removing the sacrificial material. The resulting reservoir is then filled with one or more therapeutic drugs. The drug reservoir stent allows elution of drug in the absence of a polymer binder.
134 Citations
16 Claims
-
1. A drug delivery stent for implanting in a bodily passageway, lumen or duct, comprising:
-
a radially expandable stent body formed of one or more metallic or polymer strut filaments, each strut filament having outer, inner, side and end surfaces;
a drug reservoir composed of a therapeutic drug being carried on one or more surfaces of each strut filament; and
a durable shell coating covering said drug reservoir and having at least one perforation extending through the coating. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
-
10. A method of forming a drug delivery stent comprising the steps of:
-
applying a sacrificial material to at least one surface of each strut filament of a stent body formed of one or more filaments;
applying a durable coating material to said surface of said sacrificial material, creating a durable shell;
creating at least one perforation in said durable shell, and removing said sacrificial material to form a continuous reservoir disposed between said strut filament surface and said durable shell. - View Dependent Claims (11, 12, 13, 14, 15, 16)
-
Specification