MODIFIED METHOD AND APPARATUS FOR MEASURING ANALYTES
First Claim
1. A device for measuring a concentration of a compound in a sample, comprising a source of electromagnetic radiation (EMR) that emits one or more than one wavelength of EMR, the source of EMR being operatively coupled to a power source;
- a holder for receiving a detachable receptor, the holder comprising one or more than one input in operable association with the source of EMR, one or more than one output in operable association with a detector, the one or more than one input and the one or more than output of the holder in optical alignment with one or more than one port located within the receptor, the one or more than one input and the one or more than output defining an EMR path through the holder and within the receptor, wherein, the sample when received by the receptor is placed within the EMR path;
the detector for measuring transmitted or reflected EMR received from the sample, the detector operatively coupled to a processing system;
the processing system comprising one, or more than one calibration algorithm for determining a concentration for the one or more than one compound, or a calibration table for determining the percent of the one or more than one compound.
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Accused Products
Abstract
A device for measuring a compound with in a sample both non-invasively and invasively is provided. The devise comprised a source of electromagnetic radiation (EMR) operatively coupled to a power source, one or more receptors and a detector. The one or more receptors shaped to receive a body part and a sample holder and optically coupled to the source of EMR by one or more radiation guiding elements. The radiation guiding element comprising an input in operable association with the source of EMR, and an output in operable association with a detector and coupled to a processing system.
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Citations
37 Claims
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1. A device for measuring a concentration of a compound in a sample, comprising
a source of electromagnetic radiation (EMR) that emits one or more than one wavelength of EMR, the source of EMR being operatively coupled to a power source; -
a holder for receiving a detachable receptor, the holder comprising one or more than one input in operable association with the source of EMR, one or more than one output in operable association with a detector, the one or more than one input and the one or more than output of the holder in optical alignment with one or more than one port located within the receptor, the one or more than one input and the one or more than output defining an EMR path through the holder and within the receptor, wherein, the sample when received by the receptor is placed within the EMR path;
the detector for measuring transmitted or reflected EMR received from the sample, the detector operatively coupled to a processing system;
the processing system comprising one, or more than one calibration algorithm for determining a concentration for the one or more than one compound, or a calibration table for determining the percent of the one or more than one compound. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 28)
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11. A method of determining the concentration of a compound in a sample of blood comprising,
(a) placing a receptor over a portion of a body part, the body part having a sample of blood thereon, (b) directing a source of electromagnetic radiation (EMR) through the receptor and onto the sample of blood; -
(c) measuring a quantity of the EMR reflected by, or transmitted through, the sample of blood with a detector; and
(d) determining a value of the compound in the sample of blood. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method of determining the concentration of a compound in a sample of blood comprising,
(a) placing a receptor over a portion of a body part; -
(b) lancing the body part located within the receptor to produce a sample of blood on the surface of the body part, (b) directing a source of electromagnetic radiation (EMR) through the receptor and onto the sample of blood;
(c) measuring a quantity of the EMR reflected by, or transmitted through, the sample of blood with a detector; and
(d) determining a value of the compound in the sample of blood. - View Dependent Claims (22, 23, 24, 25, 26, 27)
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29. A device for measuring one or more than one compound in a sample both non-invasively and invasively, comprising:
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a source of electromagnetic radiation (EMR) that emits one or more than one wavelength of EMR, the source of EMR being operatively coupled to a power source;
one or more than one receptor for receiving a body part and a sample holder as the sample, the one or more than one receptor optically coupled to the source of EMR by one or more than one radiation guiding element, the radiation guiding element comprising one or more than one input in operable association with the source of EMR, one or more than one output in operable association with a detector, the one or more than one input and the one or more than output in optical alignment with one or more than one port located within the one or more than one receptor, the one or more than one input and the one or more than output defining an EMR path from the source, through the one or more than one receptor and the detector, wherein, the sample when received by the one or more than one receptor is placed within the EMR path;
the detector for measuring transmitted or reflected EMR received from the sample, the detector operatively coupled to a processing system;
the processing system comprising one, or more than one calibration algorithm for determining a concentration for the one or more than one compound, or a calibration table for determining the percent of the one or more than one compound. - View Dependent Claims (30, 31, 32)
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33. A device for measuring one or more than one compound in a body part or a sample derived from a body part, comprising:
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a source of electromagnetic radiation (EMR) that emits one or more than one wavelength of EMR, the source of EMR being operatively coupled to a power source;
a receptor comprising;
one or more than one input in operable association with the source of EMR, one or more than one output in operable association with a detector, the one or more than one input and the one or more than output of the receptor in optical alignment with one or more than one port located within the receptor, the one or more than one input and the one or more than output defining an EMR path within the receptor, wherein, the body part or sample derived from a body part when received by the receptor is placed within the EMR path, and a piercing member for lancing the body part when the body part is positioned within the receptor to produce the sample derived from the body part;
the detector for measuring transmitted or reflected EMR received from the body part or from the sample, the detector operatively coupled to a processing system;
the processing system comprising one or more than one calibration algorithm for determining a concentration for the compound, and a warning unit coupled to the processing system, the warning unit producing a signal when the concentration for the one or more than one compound is outside or at a limit of a predetermined range of values of concentration for the one or more than one compound.
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34. A device for measuring one or more than one compound in a body part or a sample derived from a body part, comprising:
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a source of electromagnetic radiation (EMR) that emits one or more than one wavelength of EMR, the source of EMR being operatively coupled to a power source;
a receptor comprising;
one or more than one input in operable association with the source of EMR, one or more than one output in operable association with a detector, the one or more than one input and the one or more than one output of the receptor in optical alignment with one or more than one port located within the receptor, the one or more than one input and the one or more than output defining an EMR path within the receptor, wherein, body part or sample derived from a body part when received within the receptor is placed within the EMR path, and an automated piercing mechanism for lancing the body part when the body part is positioned within the receptor to produce the sample derived from the body part, the piercing mechanism being coupled to a processing system for determining a concentration for the compound within the body part, the piercing mechanism being activated being activated upon receiving a signal from the processing system when the concentration for the compound in the body part is outside or at a limit of a predetermined range of values of concentration for the compound;
the detector for measuring transmitted or reflected EMR received from the body part or from the sample derived from the body part, the detector operatively coupled to the processing system, and the processing system comprising one, or more than one calibration algorithm for determining a concentration for the one or more than one compound in the body part or the sample derived from the body part.
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35. A method of determining the concentration of a compound in blood within a body part comprising
(a) determining when the concentration for the compound measured using a non-invasive method is outside or at a limit of a predetermined range of values of concentration; -
(b) placing a receptor over a portion of a body part, the body part having a sample of blood thereon, (c) directing a source of electromagnetic radiation (EMR) through the receptor and onto the sample of blood;
(d) measuring a quantity of the EMR reflected by, or transmitted through, the sample of blood with a detector; and
(e) performing a quantitative mathematical analysis of the quantity of EMR using an algorithm, and determining the concentration of the compound in the sample of blood. - View Dependent Claims (36, 37)
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Specification