Urinalysis for the early detection of and recovery from worsening heart failure
First Claim
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1. A system for early detection of decompensation of heart failure, the system comprising:
- a first interface configured to receive urinalysis data, and to send the urinalysis data to a computer via a network;
a second interface configured to receive data from a cardiac rhythm management device, and to send the data from the device to the computer;
a set of instructions stored in the computer, which when executed causes the computer to access the urinalysis data and the data from the cardiac rhythm management device, and based at least in part upon the accessed data, to detect decompensation of heart failure.
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Abstract
A system and method of detecting decompensation of heart failure for a patient includes urinalysis to determine the change in physical and/or chemical composition of a patient'"'"'s urine over time. The change in chemical and/or physical composition of the patient'"'"'s urine is used to infer the onset of decompensation. Optionally, the inference is verified with other data, such as with baseline transthoracic impedance data, patient weight data, and/or blood composition data.
44 Citations
32 Claims
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1. A system for early detection of decompensation of heart failure, the system comprising:
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a first interface configured to receive urinalysis data, and to send the urinalysis data to a computer via a network;
a second interface configured to receive data from a cardiac rhythm management device, and to send the data from the device to the computer;
a set of instructions stored in the computer, which when executed causes the computer to access the urinalysis data and the data from the cardiac rhythm management device, and based at least in part upon the accessed data, to detect decompensation of heart failure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of early detection of decompensation of heart failure in a patient, comprising:
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comparing a urinalysis measurement with a first boundary to determine if the urinalysis measurement is abnormal for the patient;
comparing a measurement made by a cardiac rhythm management device with a second boundary to determine if the device measurement is abnormal for the patient; and
determining whether decompensation of heart failure is imminent for the patient on the basis of the comparisons. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
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21. A computerized method of early detection of decompensation of heart failure in a patient, comprising:
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accessing a set of urinalysis data, each datum within the data set describing a particular characteristic of the patient'"'"'s urine at a differing points in time;
determining a boundary from the accessed urinalysis data set;
comparing a data point describing the particular characteristic of the patient'"'"'s urine with the boundary; and
detecting impending decompensation of heart failure for the patient, based at least in part upon the comparison. - View Dependent Claims (22, 23, 24)
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25. A computerized method of early detection of decompensation of heart failure in a patient, comprising:
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accessing a plurality of sets of urinalysis data, wherein for a given one of the urinalysis data sets, each datum therein describes a particular characteristic of the patient'"'"'s urine at a differing points in time, and wherein each of the urinalysis data sets corresponds to a different characteristic of the patient'"'"'s urine;
determining a plurality of boundaries, each of the boundaries corresponding to a given one of the plurality of urinalysis data sets;
comparing each of a plurality of data points describing characteristics of the patient'"'"'s urine with a corresponding one of the plurality of boundaries; and
detecting impending decompensation of heart failure for the patient, based at least in part upon the comparisons. - View Dependent Claims (26, 27, 28, 29, 30, 31)
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32. A system for early detection of decompensation of heart failure, the system comprising:
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a means for obtaining urinalysis data; and
a means for detecting impending decompensation of heart failure, based upon the urinalysis data.
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Specification