Controlling neuromodulation using stimulus modalities
First Claim
1. A method for affecting a neuromodulation therapy based upon an external evoking signal applied to a patient'"'"'s body, comprising:
- applying an external evoking signal to a first target portion of a patient'"'"'s body;
receiving data relating to a physiological response resulting from applying said external evoking signal to the patient'"'"'s body;
determining a neurotransmission characteristic of said patient'"'"'s body based upon said data relating to the physiological response; and
controlling at least one parameter defining a therapeutic electrical stimulation signal provided by an implantable medical device based upon said neurotransmission characteristic to treat a disorder.
2 Assignments
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Accused Products
Abstract
A method, apparatus, and system for affecting neuromodulation based upon an evoking signal applied to a patient'"'"'s body. An internal and/or external evoking and/or therapeutic signal is applied to a first target portion of a patient'"'"'s body. Data relating to a physiological response resulting from the internal and/or external evoking and/or therapeutic signal is received. A neurotransmission characteristic of the patient'"'"'s body is determined based upon the data relating to the physiological response. At least one parameter defining an electrical therapeutic signal provided by an implantable medical device is controlled based upon the determined neurotransmission characteristic to treat a disorder.
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Citations
24 Claims
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1. A method for affecting a neuromodulation therapy based upon an external evoking signal applied to a patient'"'"'s body, comprising:
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applying an external evoking signal to a first target portion of a patient'"'"'s body;
receiving data relating to a physiological response resulting from applying said external evoking signal to the patient'"'"'s body;
determining a neurotransmission characteristic of said patient'"'"'s body based upon said data relating to the physiological response; and
controlling at least one parameter defining a therapeutic electrical stimulation signal provided by an implantable medical device based upon said neurotransmission characteristic to treat a disorder. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method for affecting a neuromodulation therapy based upon an external evoking signal applied to a patient'"'"'s body, comprising:
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applying an external evoking signal to a first target portion of a patient'"'"'s body;
receiving data relating to a physiological response resulting from applying said external evoking signal to the patient'"'"'s body;
determining a neurotransmission characteristic of said patient'"'"'s body based upon said data relating to the physiological response; and
determining at least one of a cranial nerve location and a cervical nerve location at which to couple an electrode for delivering a therapeutic electrical stimulation signal based on said neurotransmission characteristic.
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8. A method for identification of a patient as a candidate for a neurostimulation therapy based upon an external evoking signal applied to the patient'"'"'s body, comprising:
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applying an external evoking signal to a first target portion of a patient'"'"'s body;
receiving data relating to a physiological response resulting from applying said external evoking signal to the patient'"'"'s body;
determining a neurotransmission characteristic of said patient'"'"'s body based upon said data relating to the physiological response; and
determining whether said patient is a potential candidate for a neurostimulation therapy based on said neurotransmission characteristic.
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9. A method for controlling a therapeutic stimulation signal provided by an implantable medical device based upon an external signal applied to the patient'"'"'s body, comprising:
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applying a first signal to a portion of a patient'"'"'s body from a source external to said implantable medical device;
receiving data relating to a physiological response resulting from said first signal;
determining a neurotransmission characteristic of said patient'"'"'s body based upon said data relating to said physiological response; and
adjusting at least one parameter defining a therapeutic stimulation signal provided by said implantable medical device based upon said neurotransmission characteristic to treat a disorder. - View Dependent Claims (10, 11)
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12. A medical device system for providing a neurostimulation therapy, comprising:
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at least one external stimulation system for delivering a first external evoking signal to a first portion of a patient'"'"'s body; and
at least one implantable medical device (IMD) for delivering a therapeutic electrical signal to a second portion of said patient'"'"'s body, wherein said IMD comprises a controller to receive data relating to a physiological response resulting from said first external evoking signal, the controller to also determine a neurotransmission characteristic of said patient'"'"'s body based upon said data relating to the physiological response, and to control at least one parameter defining said therapeutic electrical signal based upon said neurotransmission characteristic to treat a disorder. - View Dependent Claims (13, 14, 15)
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16. A method for treating at least one of a neurological and a neuropsychiatric disorder using an implantable medical device, comprising:
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providing an evoking signal comprising at least one of a sensory stimulus, a visceral stimulus, a motor stimulus, an autonomic nervous system stimulus, and a somatosensory stimulus, to a portion of a patient'"'"'s body using a device external to a patient'"'"'s body;
detecting a physiological response to said evoking signal;
determining whether a parameter related to said physiological response exceeds a target value; and
providing a neuromodulation signal to a portion of a nerve of said patient using said implantable medical device based upon a determination that said parameter related to said physiological response exceeds said target value. - View Dependent Claims (17, 18, 19, 20)
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21. A method for performing an adaptive adjustment of a stimulation parameter of an implantable medical device, comprising:
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delivering an evoking signal to a first portion of the patient'"'"'s body using said implantable medical device;
sensing a physiological response to said evoking signal; and
adjusting at least one parameter relating to a therapeutic neuromodulation signal provided by said implantable medical device based upon said physiological response to said evoking signal. - View Dependent Claims (22, 23, 24)
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Specification