CALCIUM PHOSPHATE SALTS IN ORAL COMPOSITIONS SUITABLE AS A TOOTH REMINERALIZING AGENT
First Claim
1. An oral composition comprising a calcium phosphate salt, a first acid and a second acid, wherein upon placement of said composition in an oral cavity dissolution of said first acid begins prior to dissolution of said second acid.
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Abstract
The present invention is generally directed to an oral composition comprising a calcium phosphate salt and a combination of acids having differing solubilities in the oral cavity, for tooth mineralization or remineralization. The presence of a combination of acids in the oral composition acts to maximize the release of calcium and phosphate ions from the oral composition over an extended period of time, in order to promote the precipitation of enamel-like crystals on the surfaces of the teeth, or in subsurface regions therein.
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Citations
25 Claims
- 1. An oral composition comprising a calcium phosphate salt, a first acid and a second acid, wherein upon placement of said composition in an oral cavity dissolution of said first acid begins prior to dissolution of said second acid.
- 17. An oral composition comprising a TTCP salt, a DCPA salt, a first acid and a second acid, wherein said first acid has a solubility in an oral cavity which is greater than the solubility of said second acid.
- 20. An oral composition comprising a TTCP salt, a DCPA salt, a first acid, and a second acid, wherein, upon consumption or mastication of said composition in an oral cavity, dissolution of said first acid begins prior to dissolution of said second acid, such that said oral cavity has (i) a salivary pH that is greater than about 3 and less than about 6 for about the first 60 seconds of consumption or mastication, and thereafter (ii) has a salivary pH that is greater than about 6 and less than about 8, and further wherein the composition has a pH of less than about 6 during said consumption.
- 23. A method of remineralizing a dental lesion in the oral cavity of a human, the method comprising placing an oral composition in said oral cavity, wherein said oral composition comprises a calcium phosphate salt, a first acid and a second acid, wherein upon placement of said composition in an oral cavity dissolution of said first acid begins prior to dissolution of said second acid.
Specification