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Compartmentalised combinatorial chemistry by microfluidic control

  • US 20070184489A1
  • Filed: 12/20/2006
  • Published: 08/09/2007
  • Est. Priority Date: 03/31/2004
  • Status: Active Grant
First Claim
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1. A method for preparing a repertoire of compounds comprising the steps of:

  • (a) compartmentalising two or more sets of primary compounds into microcapsules;

    such that a proportion of the microcapsules contains multiple copies of one or more compounds representative of each of said sets, and wherein said one or more compounds form a subset of the set of primary compounds;

    (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets;

    wherein one or more of steps (a) and (b) are performed under microfluidic control.

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