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Dosage forms for the delivery of drugs of abuse and related methods

  • US 20070190142A1
  • Filed: 01/22/2007
  • Published: 08/16/2007
  • Est. Priority Date: 01/21/2006
  • Status: Abandoned Application
First Claim
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1. An abuse-deterrent drug formulation comprising a melt-processed mixture ofa) at least one abuse-relevant drug,b) at least one cellulose ether or cellulose ester, andc) at least one alkyl alkacrylate polymer, alkacrylate polymer, or a combination thereof,wherein the amount of the drug that is extracted in vitro from the formulation by 40% aqueous ethanol within one hour at 37°

  • C. is less than or equal to twice the amount of the drug that is extracted by 0.01 N hydrochloric acid within one hour at 37°

    C.; and

    wherein the drug formulation is adapted so as to be useful for oral administration to a human 3, 2, or 1 times daily.

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