System and method for the detection of physiologic response to stimulation

• US 20070191688A1
• Filed: 02/10/2006
• Published: 08/16/2007
• Est. Priority Date: 02/10/2006
• Status: Active Grant

• Current Assignee: Lawrence Lynn
• Original Assignee: Lawrence Lynn
• Inventors: Lynn, Lawrence
• Granted Patent: US 7,668,579 B2
• Time in Patent Office: Days
• US Class Current: 600/300
• CPC Class Codes: A61B 5/002 Monitoring the patient using a local or closed circuit, e.g. in a room or building A61B5/0017 takes precedence
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/028 by thermo-dilution
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/1135 by monitoring thoracic expansion
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/412 Detecting or monitoring sepsis
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/726 using Wavelet transforms
• CPC Class Codes: A61B 7/003 Detecting lung or respiration noise

Abstract

The disclosed embodiments relate to a system and method for detecting a response of a patient to an external stimulus. An exemplary method comprises the acts of generating at least one time series of at least one physiologic parameter, detecting the external stimulus, detecting at least one response associated with the stimulus, the response comprising at least one of a pattern and a value, and outputting an indication of the response.

Claims

1. A method for detecting a response of a patient to an external stimulus, comprising:

generating at least one time series of at least one physiologic parameter;

detecting the external stimulus;

detecting at least one response associated with the stimulus, the response comprising at least one of a pattern and a value; and

outputting an indication of the response.

2. The method according to claim 1, comprising receiving a signal corresponding to the physiologic parameter from an oximeter.

3. The method according to claim 1, wherein the at least one response corresponds to a peak value.

4. The method according to claim 1, wherein the value is indicative of a magnitude value.

5. The method according to claim 1, wherein the value is indicative of a magnitude of rise in oxygen saturation.

6. The method according to claim 1 wherein the external stimulus is auditory.

7. The method according to claim 1, wherein the external stimulus comprises an alarm.

8. The method according to claim 7, wherein the value is indicative of a peak value of oxygen saturation that follows the alarm.

9. The method according to claim 1, wherein the value is indicative of a peak value of oxygen saturation that follows the external stimulus.

10. The method according to claim 1, wherein the value is indicative of a magnitude of rise in oxygen saturation that follows the external stimulus.

11. The method according to claim 1, wherein the physiologic parameter is related to a plethesmographic pulse and the value is indicative of a change in a component of the plethesmographic pulse that follows the stimulus.

12. The method according to claim 1, wherein physiologic parameter is related to a plethesmographic pulse and the value is indicative of a rise in the plethesmographic pulse amplitude that follows the stimulus.

13. The method according to claim 1 wherein the external stimulus comprises a fall in oxygen saturation.

14. The method according to claim 1, wherein the value is indicative of a magnitude of rise in oxygen saturation that follows a fall in oxygen saturation.

15. The method according to claim 1, wherein the value is indicative of a peak value of oxygen saturation that follows a fall in oxygen saturation.

16. The method according to claim 1, wherein the value is indicative of a slope of rise in oxygen saturation that follows a fall in oxygen saturation.

17. The method according to claim 1, wherein the value expresses a relationship between two other values.

18. The method according to claim 1, wherein the value expresses a relationship between a fall magnitude and a rise magnitude

19. The method according to claim 1, wherein the value expresses a relationship between a fall duration and a rise duration.

20. The method according to claim 1, wherein the value is indicative of a relationship between a fall slope and a rise slope.

21. The method according to claim 1, wherein the value is indicative of a relationship between a peak value and another value.

22. The method according to claim 1, wherein the value is indicative of a relationship between a peak of the time series and a nadir of the time series.

23. A patient monitoring system, comprising:

a sensor that is adapted to produce a signal indicative of at least one time series of at least one physiologic parameter of a patient;

a processor that is adapted to analyze the signal to detect an external stimulus of the patient, to detect at least one response associated with the external stimulus, the response comprising at least one of a pattern and a value, and to output an indication of the response.

24. A system for processing data, comprising:

a memory device adapted to store data representative at least one time series of at least one physiologic parameter of a patient; and

a processor adapted to analyze the data to detect data corresponding to an external stimulus of the patient, to detect at least one response associated with the external stimulus, the response comprising at least one of a pattern and a value, and to output an indication of the response.