Systems and methods for performing acoustic hemostasis of deep bleeding trauma in limbs

• US 20070194658A1
• Filed: 07/13/2006
• Published: 08/23/2007
• Est. Priority Date: 07/13/2005
• Status: Abandoned Application

• Current Assignee: Otsuka Medical Devices Co., Ltd. (Otsuka Holdings Company Limited)
• Original Assignee: Otsuka Medical Devices Co., Ltd. (Otsuka Holdings Company Limited)
• Inventors: Zhang, Jimin, Emery, Charles, Caldwell, Ed, Kook, John, Pedersen, Robert, Perozek, David
• Application Number:
  US11/486,528
• Publication Number:
  US 20070194658A1
• Time in Patent Office: Days
• US Class Current: 310/314
• CPC Class Codes: A61B 17/1325 with means for applying local pressure pressure pads A61F5/30
• CPC Class Codes: A61B 17/135 inflatable for measuring blood pressure A61B5/022; inflatable pressure pads A61F5/34
• CPC Class Codes: A61B 5/445 Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/4227 characterised by straps, belts, cuffs or braces
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/4483 characterised by features of the ultrasound transducer
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

An inflatable cuff having integrated ultrasound transducers is used to effect hemostasis of deep bleeding wounds in limbs. The cuff includes a chamber defined by a bladder or a series of dams into which a fluid may be introduced and pressurized. The pressure of the fluid stops or slows bleeding while high intensity focused ultrasound is applied to effect hemostasis. The fluid may also serve as an acoustic couplant between the limb and the ultrasound transducers. The transducers may be electrostrictive transducers. Diodes may be used to reduce parallel capacitive loading in the transducer array. Bypass capacitors using the electrostrictive material may also be used.

Claims

1. An ultrasound applicator, comprising:

a two-dimensional array of electrostrictive transducer elements; and

at least one diode electrically connected to each transducer element.

2. The applicator of claim 1, wherein the diode is a PIN diode.

3. The applicator of claim 1, wherein the diode is a Zener diode.

4. The applicator of claim 1, wherein two diodes in parallel are electrically connected to each transducer element.

5. The applicator of claim 4, wherein the two diodes have opposite polarity.

6. The applicator of claim 1, wherein two diodes in series, which are in turn in parallel to two other diodes in series, are electrically connected to each transducer element.

7. The applicator of claim 1, comprising a conductive line electrically connected to at least one transducer element and electrically connected to at least one diode electrically connected to the at least one transducer element, wherein the line is configured to bias both the at least one transducer element and the at least one diode electrically connected to the at least one transducer element.

8. The applicator of claim 1, comprising:

a first conductive line electrically connected to at least one transducer element, wherein the first conductive line is configured to bias the at least one transducer element; and

a second conductive line electrically connected to at least one diode electrically connected to the at least one transducer element, wherein the second conductive line is configured to bias the at least one diode electrically connected to the at least one transducer element.

9. The applicator of claim 1, comprising a pressurizeable bladder coupled to the two-dimensional array.

10. The applicator of claim 9, comprising a cuff configured to deploy the pressurizeable bladder and array of transducer elements circumferentially around a body limb.

11. A method of driving the ultrasound applicator of claim 1, comprising forward biasing at least one diode connected to a transducer element that is desired to be driven.

12. The method of claim 11, comprising using a conductive line to forward bias both the at least one diode connected to the transducer element that is desired to be driven and the transducer element that are desired to be driven.

13. The method of claim 11, comprising using a first voltage for said biasing and using a second voltage to bias the transducer element that are desired to be driven, wherein the second voltage is different than the first voltage.

14. An ultrasound applicator, comprising:

a plurality of electrostrictive ultrasound transducer elements, each element comprising an electrostrictive material; and

a bypass capacitor electrically connected to at least one element, wherein the bypass capacitor comprises an electrostrictive material between two conductive plates.

15. The applicator of claim 14, wherein the electrostrictive material in the bypass capacitor is the same material as the electrostrictive material in the transducer elements.

16. The applicator of claim 15, wherein the electrostrictive material in the bypass capacitor and the transducer elements is lead-magnesium-niobate modified with lead titanate.

17. The applicator of claim 14, wherein the transducer elements are arranged in a rectangular array and wherein the applicator comprises one of said bypass capacitors for each column of transducer elements in the array.

18. The applicator of claim 14, wherein the bypass capacitor comprises a rectangular wafer of electrostrictive material with conductive plating on both sides of the wafer.

19. The applicator of claim 14, comprising a pressurizeable bladder coupled to the transducer elements.

20. The applicator of claim 19, comprising a cuff configured to deploy the pressurizeable bladder and transducer elements circumferentially around a body limb.

21. A method of driving an electrostrictive ultrasound transducer array, comprising:

voltage biasing a first set of selected electrostrictive transducer elements within the array; and

electrically shorting a second set of selected electrostrictive transducer elements within the array.

22. The method of claim 21, wherein the shorted second set of electrostrictive transducer elements are configured to act as bypass capacitors to the first set of electrostrictive transducer elements.

23. The method of claim 21, comprising electrically leaving open a third set of selected electrostrictive transducer elements within the array.

24. The method of claim 23, wherein elements within the third set of transducer elements are adjacent to elements within the first set of transducer elements.

25. The method of claim 21, comprising subsequently:

voltage biasing a fourth set of selected electrostrictive transducer elements within the array; and

electrically shorting a fifth set of selected electrostrictive transducer elements within the array, wherein at least some of the elements within the fourth set were present in the second set and wherein at least some of the elements within the fifth set were present in the first set.