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Devices and methods for enrichment and alteration of cells and other particles

  • US 20070196820A1
  • Filed: 09/15/2005
  • Published: 08/23/2007
  • Est. Priority Date: 04/05/2005
  • Status: Abandoned Application
First Claim
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1. A device for producing a sample enriched in an analyte, said device comprising:

  • (a) a first channel comprising a structure that deterministically deflects particles having a hydrodynamic size above a critical size in a direction not parallel to the average direction of flow in said structure, wherein said particles are analyte particles or are a non-analyte component of said sample; and

    (b) a reservoir fluidly coupled to an output of said first channel through which said analyte passes into said reservoir, wherein said reservoir comprises a reagent that alters a magnetic property of said analyte.

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