Phenylephrine liquid formulations
First Claim
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1. An aqueous oral pharmaceutical composition comprising:
- a). Phenylephrine;
b). artificial sweetener;
c). up to about 45% w/v glycerin; and
d). up to about 10% w/v sorbitol wherein the glycerin to sorbitol ratio is about 2;
1 to about 10;
1.
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Abstract
An oral, aqueous-based, liquid pharmaceutical composition is provided. The composition comprises up to about 45% w/v glycerin and up to about 10% w/v sorbitol wherein the glycerin to sorbitol ratio is about 2:1 to 10:1.
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Citations
41 Claims
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1. An aqueous oral pharmaceutical composition comprising:
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a). Phenylephrine; b). artificial sweetener; c). up to about 45% w/v glycerin; and d). up to about 10% w/v sorbitol wherein the glycerin to sorbitol ratio is about 2;
1 to about 10;
1. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. An aqueous pharmaceutical solution comprising:
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a). phenylephrine; b). artificial sweetener; c). about 18% to about 30% w/v glycerin; and d). about 3% to about 10% w/v sorbitol, wherein the glycerin to sorbitol ratio is about 2;
1 to about 10;
1. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26)
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27. An aqueous oral pharmaceutical suspension composition comprising:
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a). phenylephrine, b). artificial sweetener, c) a viscosity modifying agent, c). up to about 45% w/v glycerin, and d). up to about 10% w/v sorbitol wherein the glycerin to sorbitol ratio is about 2;
1 to about 10;
1. - View Dependent Claims (28, 29, 30, 31, 32, 33)
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34. A method of treating an mammal in need of treatment comprising providing an effective amount of an aqueous oral pharmaceutical composition comprising phenylephrine, artificial sweetener, up to about 45% glycerin, and up to about 10% sorbitol, wherein the glycerin to sorbitol ratio is about 2:
- 1 to about 10;
1. - View Dependent Claims (35, 36)
- 1 to about 10;
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37. An aqueous oral pharmaceutical composition comprising:
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a). an active agent selected from the group consisting of analgesics, decongestants, expectorants, anti-tussives, antipyretics, anti-inflammatory agents, cough suppressants, antihistamines and mixtures thereof; b). artificial sweetener; c). up to about 45% w/v glycerin; and d). up to about 10% w/v sorbitol wherein the glycerin to sorbitol ratio is about 2;
1 to about 10;
1. - View Dependent Claims (38, 39, 40, 41)
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Specification