Porous Body Having Biocompatibility And Method For Producing The Same

• US 20070197701A1
• Filed: 03/17/2005
• Published: 08/23/2007
• Est. Priority Date: 03/25/2004
• Status: Active Grant

• Current Assignee: Seiren Company Limited
• Original Assignee: Seiren Company Limited
• Inventors: Yamada, Hideyuki, Kato, Yoichi, Tsujimoto, Kazuhisa
• Granted Patent: US 7,763,448 B2
• Time in Patent Office: Days
• US Class Current: 524/256
• CPC Class Codes: A61L 27/227 Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
• CPC Class Codes: A61L 27/56 Porous materials, e.g. foams or sponges
• CPC Class Codes: Y10S 530/812 Peptides or proteins is immobilized on, or in, an organic carrier

Abstract

The present invention provides a porous body high in safety against environment and living bodies and having a strength high enough to withstand practical use, said porous body comprising, as a skeleton constituent thereof, sericin with an average molecular weight of 30000 to 400000, and having a recovery rate of 10 to 100% after 50% compression.

Claims

1. A porous body comprising, as a skeleton constituent threof, sericin with an average molecular weight of 30000 to 400000, and having a recovery rate of 10 to 100% after 50% compression.

2. The porous body of claim 1 having an average pore diameter of 0.1 to 5000 μ

m.

3. The porous body of claim 1 having a porosity of 70 to 99%.

4. The porous body of claim 1 further containing a functional substance in an immobilized state.

5. The porous body of claim 4 wherein the functional substance is a living body-derived substance.

7. The porous body of claim 2 having a porosity of 70 to 99%.

8. The porous body of claim 7 further containing a functional substance in an immobilized state.

9. The porous body of claim 2 further containing a functional substance in an immobilized state.

10. The porous body of claim 3 further containing a functional substance in an immobilized state.

11. The porous body of claim 10 wherein the functional substance is a living body-derived substance.

12. The porous body of claim 9 wherein the functional substance is a living body-derived substance.

13. The porous body of claim 8 wherein the functional substance is a living body-derived substance.

6. A method for producing a porous body which comprises gelling an aqueous solution containing sericin with an average molecular weight of 30000 to 400000, thereafter freezing the resulting gels and then melting the frozen gels.