Antioxidant compositions for the eye

• US 20070207116A1
• Filed: 03/01/2006
• Published: 09/06/2007
• Est. Priority Date: 03/01/2006
• Status: Abandoned Application

• Current Assignee: David Brown
• Original Assignee: David Brown
• Inventors: Brown, David
• Application Number:
  US11/365,731
• Publication Number:
  US 20070207116A1
• Time in Patent Office: Days
• US Class Current: 424/78.300
• CPC Class Codes: A61K 31/717 Celluloses
• CPC Class Codes: A61K 31/728 Hyaluronic acid
• CPC Class Codes: A61K 38/36 Blood coagulation or fibrinolysis factors
• CPC Class Codes: A61K 38/40 Transferrins, e.g. lactoferrins, ovotransferrins

Abstract

Ophthalmic compositions comprising at least one antioxidant agent chosen from a carotenoid, glutathione, reduced glutathione, glutathione enhancers, a lipoic acid, a flavonoid, an oleanoic acid, ascorbyl palmitate, aloe vera extract, an omega-6 fatty acid, melatonin, and vitamin E acetate.

Claims

1. An ophthalmic composition comprising at least one antioxidant agent chosen from a carotenoid, glutathione, reduced glutathione, glutathione enhancers, a lipoic acid, a flavonoid, an oleanoic acid, ascorbyl palmitate, aloe vera extract, an omega-6 fatty acid, melatonin, and vitamin E acetate.

2. The composition of claim 1, further comprising a lubricating agent.

3. The composition of claim 1, further comprising at least one lubricating agent chosen from a cellulose derivative, sodium carboxymethyl cellulose, hydroxypropyl methylcellulose, glycerin, polyvinyl alcohol, polyvinylpyrrolidone, povidone, propylene glycol, mineral oil, lactoferrin, and albumin.

4. The composition of claim 1, further comprising at least one additional component chosen from a vehicle, a buffer, an organic carrier, an inorganic carrier, an emulsifier, a wetting agent, an anti-inflammatory agent, a penetration enhancer, a nerve sheath protectant, a nitric oxide synthase inhibitor, a hyaluronic acid, a collagen, and a preservative.

5. The composition of claim 1, further comprising 0.4% aloe vera extract, 0.5% zinc sulfate heptahydrate, and 0.01% benzalkonium chloride.

6. The composition of claim 1, further comprising 1% resveratrol, 0.3% glycerin, 1% propylene glycol, 0.01% benzalkonium chloride, and 0.025% EDTA.

7. The composition of claim 1, further comprising 0.5% lutein, 0.2% zeaxanthin, and 0.2% hydroxypropyl methylcellulose.

8. The composition of claim 1, further comprising 0.4% aloe vera extract, 1% propylene glycol, 0.3% glycerin, 0.01% benzalkonium chloride, 0.75% benzalkonium chloride, 0.75% boric acid, 0.025% disodium edetate.

9. A method for treating an eye comprising administering to the eye an ophthalmic composition comprising at least one antioxidant agent chosen from a carotenoid, glutathione, reduced glutathione, glutathione enhancers, a lipoic acid, a flavonoid, an oleanoic acid, ascorbyl palmitate, aloe vera extract, an omega-6 fatty acid, melatonin, and vitamin E acetate.

10. The method of claim 9, wherein the ophthalmic composition further comprises a lubricating agent.

11. The method of claim 9, wherein the ophthalmic composition further comprises at least one lubricating agent chosen from a cellulose derivative, sodium carboxymethyl cellulose, hydroxypropyl methylcellulose, glycerin, polyvinyl alcohol, polyvinylpyrrolidone, povidone, propylene glycol, mineral oil, lactoferrin, and albumin.

12. The method of claim 9, wherein the ophthalmic composition further comprises at least one additional component chosen from a vehicle, a buffer, an organic carrier, an inorganic carrier, an emulsifier, a wetting agent, an anti-inflammatory agent, a penetration enhancer, a nerve sheath protectant, a nitric oxide synthase inhibitor, a hyaluronic acid, a collagen, and a preservative.

13. The method of claim 9, wherein the ophthalmic composition further comprises 0.4% aloe vera extract, 0.5% zinc sulfate heptahydrate, and 0.01% benzalkonium chloride.

14. The method of claim 9, wherein the ophthalmic composition further comprises 1% resveratrol, 0.3% glycerin, 1% propylene glycol, 0.01% benzalkonium chloride, and 0.025% EDTA.

15. The method of claim 9, wherein the ophthalmic composition further comprises 0.5% lutein, 0.2% zeaxanthin, and 0.2% hydroxypropyl methylcellulose.

16. The method of claim 9, wherein the ophthalmic composition further comprises 0.4% aloe vera extract, 1% propylene glycol, 0.3% glycerin, 0.01% benzalkonium chloride, 0.75% benzalkonium chloride, 0.75% boric acid, 0.025% disodium edetate.