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Compositions for regenerating tissue that has deteriorated, and methods for using such compositions

  • US 20070207131A1
  • Filed: 04/30/2007
  • Published: 09/06/2007
  • Est. Priority Date: 05/22/1998
  • Status: Abandoned Application
First Claim
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1. A method for repairing tissue that has been damaged in a subject, wherein the method comprises:

  • a) providing a pharmaceutical composition comprising;

    (i) autologous passaged fibroblasts substantially free of proteins derived from xenogeneic serum of xenogeneic serum-containing culture medium; and

    (ii) a pharmaceutically acceptable carrier;

    b) identifying a site in the subject of;

    (i) tissue degeneration due to a disease or disorder;

    or (ii) a tissue defect, wherein the tissue degeneration or the tissue defect in the subject comprises a defect of an oral mucosa, trauma to an oral mucosa, trauma to an oral bone, periodontal disease, diabetes, cutaneous ulcers, or venous stasis; and

    c) injecting a therapeutically effective amount of the pharmaceutical composition subadjacent to the tissue degeneration or defect, wherein the injecting results in repair of the tissue degeneration or the defect

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