APPETITE SUPPRESSION DEVICE

• US 20070207199A1
• Filed: 12/28/2006
• Published: 09/06/2007
• Est. Priority Date: 12/28/2005
• Status: Abandoned Application

• Current Assignee: Stephen Sogin
• Original Assignee: Stephen Sogin
• Inventors: Sogin, Stephen
• Application Number:
  US11/617,532
• Publication Number:
  US 20070207199A1
• Time in Patent Office: Days
• US Class Current: 424/451
• CPC Class Codes: A61K 9/0065 Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
• CPC Class Codes: A61K 9/4808 characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release capsules filled with granules or microparticles A61K9/16; filled with microcapsules or coated microparticles A61K9/50; with mixture of different granules, microcapsules, (coated) microparticles A61K9/5084

Abstract

An appetite suppression device includes an ingestible, expandable membrane in surrounding an expandable reactant material. The membrane is contained in a capsule. A reactant enabling mechanism is integrated with the expandable membrane to enable the reactant after ingestion of the membrane by a subject. enabling mechanism may comprise a pore in one portion of the membrane. Alternatively, the enabling mechanism may be a separation of the membrane into two portions, each having materials which, when combined, react to expand the membrane.

Claims

1. An appetite suppression device, comprising:

a dissolvable capsule;

an expandable membrane in the capsule surrounding an expandable reactant material, the expandable member including an open pore allowing entrance of liquid into the membrane after ingestion of the capsule by a subject.

2. The device of claim 1 wherein the reactant enabling mechanism includes a valve structure positioned in the opening of the membrane to allow stomach acid from the subject to enter the expandable membrane.

3. The device of claim 2 wherein the valve structure includes a mesh cover.

4. The device of claim 3 wherein the valve structure includes a valve cover sealing the mesh cover.

5. The device of claim 1 wherein the expandable reactant is sodium bicarbonate.

6. The device of claim 1 wherein the expandable reactant is a combination of sodium bicarbonate and citric acid.

7. The device of claim 1 wherein the pore is associated with a structure such that the membrane is oriented with the pore at the bottom of the membrane after injection.

8. The device of claim 7 wherein the structure is a weight positioned proximate to the opening.

9. The device of claim 1 wherein the membrane is composed of latex.

10. The device of claim 1 wherein the membrane is composed of polyurethane.

11. The device of claim 1 wherein the membrane has a porosity allowing deflation of an inflated membrane cause by reaction of the expandable reactant within a predefined time period.

12. The device of claim 11 wherein the predefined time period is 24 hours.

13. An ingestible appetite suppression device comprising:

an expandable membrane;

an expandable reactant in the expandable membrane;

a dissolvable container surrounding the membrane and reactant; and

an open pore integrated in the expandable membrane.

14. The device of claim 13 further including a weight adjacent to the pore.

15. The device of claim 13 further including a mesh cover over the pore.

16. The device of claim 13 further including a valve assembly covering the pore upon expansion of the membrane.

17. An appetite suppression device, comprising:

a dissolvable capsule; and

an expandable membrane in the capsule surrounding an expandable reactant material, the expandable membrane including a twisted portion dividing the membrane into first section including the expandable reactant and a second section.

18. The device of claim 17 wherein the second section includes a liquid reactant material.

19. The device of claim 18 wherein the liquid reactant dissolves the expandable reactant to inflate the balloon upon un-twisting of the twisted portion.

20. The device of claim 17 wherein the expandable reactant is sodium bicarbonate.

21. The device of claim 17 wherein the expandable reactant is a combination of sodium bicarbonate and citric acid.

22. The device of claim 17 wherein the membrane is composed of latex.

23. The device of claim 17 wherein the membrane is composed of polyurethane.

24. The device of claim 17 wherein the membrane has a porosity allowing deflation of an inflated membrane cause by reaction of the expandable reactant within a predefined time period.

25. The device of claim 17 wherein the predefined time period is 24 hours.

26. A method for suppressing appetite in a subject, comprising:

determining a dosage comprising a number of appetite suppression devices based on a stomach size of the subject;

administering one or more self-expanding appetite suppression devices; and

evaluating the subject using an ultrasound test after expansion of the appetite suppression devices.

27. The method of claim 26 wherein the step of determining determines a dosage of between one and five devices.

28. The method of claim 26 wherein the step of determining includes using a device having an inflated volume of between 50-500 milliliters.

29. The method of claim 26 wherein the step of administering comprises administering a dissolvable capsule including an expandable membrane in the capsule surrounding an expandable reactant material, the expandable member including an open pore allowing entrance of liquid into the membrane after ingestion of the capsule by a subject.

30. The method of claim 26 wherein the step of administering comprises administering a dissolvable capsule including an expandable membrane in the capsule surrounding an expandable reactant material, the expandable membrane including a twisted portion dividing the membrane into first section including the expandable reactant and a second section.