APPETITE SUPPRESSANT COMPOSITIONS

• US 20070207227A1
• Filed: 09/12/2006
• Published: 09/06/2007
• Est. Priority Date: 02/23/2006
• Status: Abandoned Application

• Current Assignee: Conopco (Unilever PLC)
• Original Assignee: Conopco (Unilever PLC)
• Inventors: POVEY, Kevin John, REES, Daryl David, ABRAHAMSE, Salomon Leendert
• Application Number:
  US11/458,698
• Publication Number:
  US 20070207227A1
• Time in Patent Office: Days
• US Class Current: 424/769
• CPC Class Codes: A23L 23/00 Soups; Sauces soya sauce A23L27/50; salad dressings, mayonnaise or ketchup A23L27/60; Preparation or treatment thereof
• CPC Class Codes: A23L 33/105 Plant extracts, their artificial duplicates or their derivatives
• CPC Class Codes: A23L 33/12 Fatty acids or derivatives thereof
• CPC Class Codes: A23L 7/126 Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars
• CPC Class Codes: A61K 36/27 Asclepiadaceae (Milkweed family), e.g. hoya
• CPC Class Codes: A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system
• CPC Class Codes: A61P 3/04 Anorexiants; Antiobesity agents

Abstract

An inherently nourishing edible appetite suppressant product comprising a steroidal glycoside, preferably obtainable from plants of the Asclepiadaceae family, the product being in the unit serving, having a weight of from 20 to 600 grams, and having the energy density of from 1.6 to 23 kilojoules per gram of product. A dietary regimen is also disclosed.

Claims

1-3. -3. (canceled)

15-16. -16. (canceled)

21. (canceled)

24-26. -26. (canceled)

29-30. -30. (canceled)

31. A method of achieving reduction in daily energy intake in a human, the method comprising administering orally to the human an edible appetite suppressant product comprising a balanced amount of steroidal glycosides and energy content.

wherein the product is in the form of an individually packaged separate bars, each bar having a weight of from about 20 g to about 100 g and each bar having the energy density from about 10 kJ/g to about 20 kJ/g;

and

wherein each bar comprises from about 50 to about 2000 mg of steroidal glycosides; and

wherein each bar comprises a mixture of fats, proteins, and carbohydrates in amounts such as to provide from about 0.5% to about 55% energy from fat, from about 3% to about 50% energy from protein, and from about 10% to about 75% energy from carbohydrate;

whereby the balanced amounts of the steroidal glycoside and the energy density are such as to achieve the reduction in daily energy intake of from about 500 kJ per day to about 5000 kJ per day.

4. The method of claim 31, wherein the steroidal glycoside is obtainable from plants of the Asclepiadaceae family.

5. The method of claim 4, wherein the steroidal glycoside is obtainable from genera of plants selected from the group consisting of Hoodia, Caralluma, Orbea, Stapelia, Lavrania, and mixtures thereof

6. The method of claim 4, wherein the steroidal glycoside is obtainable from the plants selected from the group consisting of Trichocaulon piliferum, Trichocaulon officinale, Hoodia currorii, Hoodia gordonii, Hoodia lugardii and mixtures thereof.

9. The method of claim 31 wherein the steroidal glycoside is incorporated into the product in the form of an extract obtainable from plants.

10. The method according to claim 9 wherein the extract comprises at least about 10% of the steroidal glycoside, by weight of the extract.

11. The method according to claim 9 wherein the extract comprises at least about 20% of the steroidal glycoside, by weight of the extract.

12. The method according to claim 9 wherein the extract comprises at least about 60% of the steroidal glycoside, by weight of the extract.

13. The method of claim 31 wherein the steroidal glycoside comprises a deoxy or a di-deoxy glycoside.

14. The method of claim 31, wherein the steroidal glycoside has the general Formula (1):

wherein

R=alkyl;

R¹ is selected from the group consisting of H, alkyl, tiglyol, benzoyl and an organic ester group;

R² is selected from the group consisting of H, or one or more 6-deoxy carbohydrates, or one or more 2,6-dideoxy carbohydrates, glucose radical, and mixtures thereof thereof; and

wherein the broken lines indicate the optional presence of a further bond between carbon atoms C4 and C5 or between carbon atoms C5 and C6.

17. The method according to claim 31, wherein fat provides from about 2% to about 45% of the energy density.

18. The method according to claim 31, wherein fat provides from about 5% to about 40% of the energy density.

19. The method of claim 31, wherein from about 10 to about 80%, by weight of the fat, is unsaturated or polyunsaturated oil.

20. The method of claim 31, wherein the product contains at least 1 g of linoleic and/or linolenic acid.

22. The method of claim 31, wherein protein provides from about 5% to about 45% of the energy density.

23. The method of claim 31, wherein protein provides from about 10% to about 35% of the energy density.

27. The method according to claim 31, the method comprising administering from 1 to 5 of the products per day.

28. The method according to claim 31, the method comprising administering from 1 to 3 of the products per day.

32. A method of achieving reduction in daily energy intake in a human, the method comprising administering orally to the human an edible appetite suppressant product comprising a balanced amount of steroidal glycosides and energy content delivered by a mixture of proteins, fats and carbohydrates,

wherein the product is in the form of an individually packaged separate drinks. each drink having a weight of from about 80 ml to about 500 ml and each drink having the energy density from about 1.6 kJ/g to about 10 kJ/g;

and

wherein each drink comprises from about 50 to about 2000 mg of steroidal glycosides; and

wherein each drink comprises a mixture of fats, proteins, and carbohydrates in amounts such as to provide from about 0.5% to about 55% energy from fat, from about 3% to about 50% energy from protein, and from about 10% to about 75% energy from carbohydrate;

whereby the balanced amounts of the steroidal glycoside and the energy density are such as to acheive the reduction in daily energy intake of from about 500 kJ per day to about 5000 kJ per day.

33. The method according to claim 32, wherein the steroidal glycoside is obtainable from plants of the Asclepiadaceae family.

34. The method according to claim 32, wherein the steroidal glycoside is obtainable from genera of plants selected from the group consisting of Hoodia, Caralluma, Orbea, Stapelia, Lavrania, and mixtures thereof.

35. The method according to claim 32, wherein the steroidal glycoside is obtainable from the plants selected from the group consisting of Trichocaulon piliferum, Trichocaulon officinale, Hoodia currorii, Hoodia lugardii and mixtures thereof.

36. The method according to claim 32 wherein the steroidal glycoside is incorporated into the product in the form of a concentrated preparation obtainable from plants.

37. The method according to claim 32 wherein the concentrated preparation comprises at least about 10% of the steroidal glycoside, by weight of the concentrated preparation.

38. The method according to claim 32 wherein the steroidal glycoside is incorporated into the product in the form of an extract obtainable from plants.

39. The method according to claim 32 wherein the extract comprises at least about 10% of the steroidal glycoside, by weight of the extract.

40. The method according to claim 32 wherein the extract comprises at least about 20% of the steroidal glycoside, by weight of the extract.

41. The method according to claim 32 wherein the extract comprises at least about 60% of the steroidal glycoside, by weight of the extract.

42. The method according to claim 32 wherein the steroidal glycoside comprises a deoxy or a di-deoxy glycoside.

43. The method according to claim 32, wherein the steroidal glycoside has the general Formula (1):

wherein

R=alkyl;

R₁ is selected from the group consisting of H, alkyl, tiglyol, benzoyl and an organic ester group;

R₂ is selected from the group consisting of H, or one or more 6-deoxy carbohydrates, or one or more 2,6-dideoxy carbohydrates, glucose radical, and mixtures thereof thereof; and

wherein the broken lines indicate the optional presence of a further bond between carbon atoms C4 and C5 or between carbon atoms C5 and C6.

44. The method according to claim 32, wherein fat provides from about 2% to about 45% of the energy density.

45. The method according to claim 32, wherein fat provides from about 5% to about 40% of the energy density.

46. The method according to claim 32, wherein from about about 10 to about 80%, by weight of the fat, is unsaturated or polyunsaturated oil.

47. The method according to claim 32, wherein the product contains at least 1 g of linoleic and/or linolenic acid.

48. the method according to claim 32, wherein protein provides from about 5% to about 45% of the energy density.

49. The method according to claim 32, wherein protein provides from about 10% to about 35% of the energy density.

50. The method according to claim 32, the method comprising administering from 1 to 5 of the products per day.

51. The method according to claim 32, the method comprising administering from 1 to 3 of the products per day.