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Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders

  • US 20070212337A1
  • Filed: 01/31/2007
  • Published: 09/13/2007
  • Est. Priority Date: 02/01/2006
  • Status: Abandoned Application
First Claim
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1. An isolated antibody-nucleic acid or peptide-nucleic acid conjugate comprising:

  • i) an antibody or peptide that specifically binds to a cellular component of;

    a) a tumor cell;

    b) tumor vasculature; and

    /or c) a component of a tumor microenvironment; and

    ii) one or more immunostimulatory nucleic acid sequences (INAS), wherein one or more of the nucleic acid sequences comprise a pathogen-associated molecular pattern (PAMP).

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