Thrombus Detecting Apparatus, Thrombus Treating Apparatus And Methods Therefor

• US 20070213613A1
• Filed: 11/14/2003
• Published: 09/13/2007
• Est. Priority Date: 11/14/2003
• Status: Active Grant

• Current Assignee: Hitachi Medical Corporation (Hitachi, Ltd.)
• Original Assignee: Hitachi Medical Corporation (Hitachi, Ltd.)
• Inventors: Kubota, Jun, Ishida, Kazunari, Kaga, Mikihiro, Fujita, Naoto
• Granted Patent: US 7,789,830 B2
• Time in Patent Office: Days
• US Class Current: 600/439
• CPC Class Codes: A61B 17/22004 using mechanical vibrations, e.g. ultrasonic shock waves A61B17/225 takes precedence
• CPC Class Codes: A61B 17/2256 with means for locating or checking the concrement, e.g. X-ray apparatus, imaging means A61B17/2255 takes precedence
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2017/22088 ultrasound absorbing, drug activated by ultrasound
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02028 Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/6822 Neck
• CPC Class Codes: A61B 8/00 Diagnosis using ultrasonic, sonic or infrasonic waves imaging of objects using sonar G01S15/00
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence

Abstract

A thrombus detecting apparatus provided with: a transducer (10), which is attached to a monitor portion of a subject and transmits and receives ultrasonic waves, a transmitter and receiver unit (11), which transmits and applies driving pulses to the transducer (10) and receives echo signals output from the transducer, and a detector (12) making use of ultrasonic waves, which processes output signals of the transmitter and receiver unit (11) and detects a thrombus passing through a blood vessel, and/or a light source (21), which generates living body inspection light, a probe (22), which is attached to a monitor portion of the subject and irradiates the living body inspection light from the light source (21) to the subject, a light receiving unit (25), which receives living body inspection light irradiated from the probe (22) and passed through the subject and outputs electrical signals depending on the intensity of the received living body inspection light, and a detector (26) making use of living body light, which processes the output signals of the light receiving unit (25) and detects a thrombus passing through a blood vessel.

Claims

1. A thrombus detecting apparatus comprising:

a transducer, which is attached to a monitor portion of a subject and transmits and receives ultrasonic waves,

a transmitter and receiver unit, which transmits and applies driving pulses to the transducer and receives echo signals output from the transducer, and

a detector making use of ultrasonic waves, which processes output signals of the transmitter and receiver unit and detects a thrombus passing through a blood vessel, and/or

a light source, which generates living body inspection light,

a probe, which is attached to a monitor portion of the subject and irradiates the living body inspection light from the light source to the subject,

a light receiving unit, which receives living body inspection light irradiated from the probe and passed through the subject and outputs electrical signals depending on the intensity of the received living body inspection light, and

a detector making use of living body light, which processes the output signals of the light receiving unit and detects a thrombus passing through a blood vessel.

2. A thrombus detecting apparatus according to claim 1, characterized in that the thrombus detecting apparatus further comprising an alarm device, which generates an alarm based on the detection result of the detector making use of ultrasonic waves and/or making use of living body light.

3. A thrombus detecting apparatus according to claim 1 or 2, characterized in that the thrombus detecting apparatus further comprising a portable self power source.

4. A thrombus treating apparatus comprising the thrombus detecting apparatus according to claim 1, 2 or 3, which is provided with a treatment use ultrasonic wave generating device transmitting ultrasonic waves for dissolving a thrombus flowing through the blood vessel based on the detection result of the detector making use of ultrasonic waves and/or making use of living body light.

5. A thrombus treating apparatus according to claim 4, characterized in that the thrombus treating apparatus further comprising:

a living body light measurement apparatus, which observably displays a state of blood stream in the blood vessel, and

an injection device, which injects thrombus dissolving agent into the blood vessel depending on the state of blood stream in the blood vessel observed by the living body light measurement apparatus.

6. A thrombus treating apparatus according to claim 5, characterized in that the thrombus treating apparatus further comprising:

a control device, which monitors the injection amount of the thrombus dissolving agent by the injection device and the transmission time of the ultrasonic waves by the treatment use ultrasonic generating device and adjusts and controls the injection amount and the irradiation time.

7. A thrombus treating apparatus according to claim 6, characterized in that the thrombus treating apparatus further comprising:

a thrombus dissolving agent activation use ultrasonic wave generating device, which transmits ultrasonic waves for activating the thrombus dissolving agent injected into the blood vessel from the injection device attached to the subject.

8. A thrombus treating method comprising:

a step of transmitting and/or irradiating ultrasonic waves and/or living body inspection light from an ultrasonic wave transducer and/or a living body light measurement probe attached at a monitor portion of a subject toward a blood vessel at the monitor portion,

a step of measuring echo signals and/or penetrating living body light from the blood vessel at the monitor portion, and

a step of detecting a thrombus flowing in the blood vessel at the monitor portion based on the intensity of the measured echo signals and/or penetrating living body light.

9. A thrombus treating method according to claim 8 further comprising:

a step of generating an alarm when the thrombus detection number in the detecting step reaches a predetermined number.

10. A thrombus treating method according to claim 8 or 9 further comprising:

a step of transmitting treatment use ultrasonic waves toward the blood vessel from the treatment use transducer attached to the subject for dissolving a thrombus passing through the blood vessel when a thrombus is detected in the detecting step or when an alarm is generated in the alarming step.

11. A thrombus treating method according to claim 10 further comprising:

a step of observing and displaying a state of blood stream in the blood vessel by attaching a living body light measurement apparatus to the subject,

a step of injecting a thrombus dissolving agent into the blood vessel depending on the observed and displayed state of blood stream in the blood vessel.

12. A thrombus treating method according to claim 11 further comprising:

a step of monitoring the transmission time of the treatment use ultrasonic waves and the injection amount of the thrombus dissolving agent and interrupting the transmission of the treatment use ultrasonic waves and the injection of the thrombus dissolving agent when a predetermined transmission time and a predetermined amount are reached.

13. A thrombus treating method according to claim 12 further comprising:

a step of transmitting thrombus dissolving agent activation use ultrasonic waves for activating the injected thrombus agent toward the blood vessel.