Rubidium elution system control
First Claim
1. A method of controlling an 82Sr/82Rb elution system having a generator valve for proportioning a flow of saline solution between an 82Sr/82Rb generator and a bypass line coupled to an outlet of the generator such that saline solution traversing the bypass line will merge with eluted saline solution emerging from the generator to provide an active saline solution, the method comprising steps of:
- during each elution run;
obtaining a plurality of successive concentration parameter values at predetermined intervals, each concentration parameter value being indicative of a respective instantaneous activity concentration of the active saline solution;
computing respective error values between each concentration parameter value and a target activity concentration value of the elution run; and
accumulating error data based on a plurality of the computed error values; and
between successive elution runs, adjusting at least one performance parameter of the elution system based on the accumulated error data.
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Abstract
A method of controlling an 82Sr/82Rb elution system having a generator valve for proportioning a flow of saline solution between an 82Sr/82Rb generator and a bypass line coupled to an outlet of the generator such that saline solution traversing the bypass line will merge with eluted saline solution emerging from the generator to provide an active saline solution. During each elution run, a plurality of successive concentration parameter values are obtained at predetermined intervals. Each concentration parameter value is indicative of a respective instantaneous activity concentration of the active saline solution. Respective error values between each concentration parameter value and a target activity concentration value of the elution run are computed. Error data based on a plurality of the computed error values is accumulated. Between successive elution runs, at least one performance parameter of the elution system is adjusted based on the accumulated error data.
48 Citations
20 Claims
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1. A method of controlling an 82Sr/82Rb elution system having a generator valve for proportioning a flow of saline solution between an 82Sr/82Rb generator and a bypass line coupled to an outlet of the generator such that saline solution traversing the bypass line will merge with eluted saline solution emerging from the generator to provide an active saline solution, the method comprising steps of:
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during each elution run;
obtaining a plurality of successive concentration parameter values at predetermined intervals, each concentration parameter value being indicative of a respective instantaneous activity concentration of the active saline solution;
computing respective error values between each concentration parameter value and a target activity concentration value of the elution run; and
accumulating error data based on a plurality of the computed error values; and
between successive elution runs, adjusting at least one performance parameter of the elution system based on the accumulated error data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A positron detector for detecting instantaneous 82Rb activity concentration of an active saline solution generated by an 82Sr/82Rb elution system, the positron detector comprising:
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a scintillation fiber disposed adjacent a feed line for conveying the active saline solution;
a photon counter operatively coupled to the scintillation fiber for detecting photons generated by positron annihilation within the scintillation fiber; and
a radiation shield surrounding the scintillation fiber and at least a portion of the feed line, for shielding at least the scintillation fiber from spurious radiation. - View Dependent Claims (19, 20)
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Specification