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Diagnostic System For Otolaryngologic Pathogens And Use Thereof

  • US 20070218459A1
  • Filed: 09/20/2004
  • Published: 09/20/2007
  • Est. Priority Date: 09/19/2003
  • Status: Abandoned Application
First Claim
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1. A method of detecting presence of an otolaryngologic pathogen in a biological sample:

  • providing a sensor device comprising (i) a substrate having two or more nucleic acid probes respectively confined to two or more distinct locations thereon, and (ii) a detector that detects the binding of target nucleic acids of a biological sample to the two or more nucleic acid probes, wherein a target nucleic acid is specific to one or more otolaryngologic pathogens;

    exposing the biological sample, or a portion thereof, to the sensor device under conditions effective to allow hybridization between the two or more nucleic acid probes and a target nucleic acid to occur; and

    detecting with the detector whether any target nucleic acid hybridizes to the two or more nucleic acid probes, wherein hybridization indicates presence of the otolaryngologic pathogen in the biological sample and presence of more than one otolaryngologic pathogen can be detected simultaneously.

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