Immune Response Associated Proteins
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Abstract
Various embodiments of the invention provide human immune response associated proteins (IRAP) and polynucleotides which identify and encode IRAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of IRAP.
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Citations
143 Claims
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1-125. -125. (canceled)
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126. An isolated polypeptide selected from the group consisting of:
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(a) a polypeptide comprising an amino acid sequence of SEQ ID NO;
1;
(b) a biologically active fragment of the polypeptide of (a); and
(c) an immunogenic fragment of the polypeptide of (a). - View Dependent Claims (127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142)
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143. An isolated polynucleotide selected from the group consisting of:
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(i) a polynucleotide comprising a polynucleotide sequence of SEQ ID NO;
2;
(ii) a polynucleotide comprising a naturally occurring polynucleotide sequence at least 90% identical to SEQ ID NO;
2;
(iii) a polynucleotide comprising a portion of the polynucleotide sequence of SEQ ID NO;
2 that specifically identifies SEQ ID NO;
2.(iv) a polynucleotide comprising a polynucleotide complementary to the polynucleotide of (i), (ii), or (iii);
(v) an RNA equivalent of the polynucleotide of (i), (ii), (iii) or (iv);
(vi) a polynucleotide of (i), (ii) or (iii) further comprising a promoter sequence operably linked to said polynucleotide of (i), (ii) or (iii).
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Specification