Optical Imaging Balloon Catheters

• US 20070219451A1
• Filed: 03/02/2007
• Published: 09/20/2007
• Est. Priority Date: 03/03/2006
• Status: Abandoned Application

• Current Assignee: Prescient Medical, Inc.
• Original Assignee: Prescient Medical, Inc.
• Inventors: Kula, John, Green, Nicholas
• Application Number:
  US11/681,312
• Publication Number:
  US 20070219451A1
• Time in Patent Office: Days
• US Class Current: 600/476
• CPC Class Codes: A61B 1/00082 Balloons
• CPC Class Codes: A61B 1/00165 with light-conductive means, e.g. fibre optics A61B1/07 takes precedence
• CPC Class Codes: A61B 1/00177 for 90 degrees side-viewing
• CPC Class Codes: A61B 1/00179 for off-axis viewing
• CPC Class Codes: A61B 1/3137 for examination of the interior of blood vessels
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/0071 by measuring fluorescence emission
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/0086 using infrared radiation
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61M 2025/1086 having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence

Abstract

The present invention provides balloon catheters in which lateral-viewing optical components for interrogating the walls of blood vessel lumens are disposed within the lumen of the balloon(s). Advantageously, low pressure compliant balloons are used to minimize the possibility of injury to the blood vessels. The expanded balloons at least substantially clear blood from the optical path between the vessel wall that is interrogated and the lateral-viewing optics.

Claims

1. An optical catheter for optically interrogating blood vessel walls, comprising:

an elongate catheter body having a distal end and a proximal end;

a balloon section of the catheter comprising;

a low-pressure inflatable balloon outwardly and radially disposed on the catheter, wherein the lumen of the balloon is in fluid communication with the proximal end of the catheter to permit inflation and deflation of the balloon; and

side-viewing optics disposed within the balloon section such that light can be emitted laterally through the balloon toward a vessel wall and can be received for analysis.

2. The catheter of claim 1, wherein the balloon is inflatable by 3 ATMs or less pressure.

3. The catheter of claim 2, wherein the balloon is inflatable by 2 ATMs or less pressure.

4. The catheter of claim 1, wherein the balloon in its expanded state has a circular profile transverse to the longitudinal axis of the catheter body.

5. The catheter of claim 4, wherein the balloon is at least substantially sphere-shaped in its expanded state.

6. The catheter of claim 1, wherein the balloon is helically shaped along the longitudinal axis of the catheter body, so that a helical groove permitting the passage of blood while the balloon is in its expanded state in a blood vessel extends from the proximal end of the balloon to the distal end of the balloon.

7. The catheter of claim 1, wherein the balloon comprises a helically shaped groove that extends from the proximal end of the balloon to the distal end of the balloon so that the passage of blood is permitted while the balloon is in an expanded state in a blood vessel.

8. The catheter of claim 1, further comprising:

at least one optical fiber that longitudinally spans the body of the catheter from its proximal end to the side-viewing optics so that light transmitted from the proximal end of the catheter can be directed to a blood vessel wall and light received from a blood vessel wall can be transmitted out of the catheter for analysis.

9. The catheter of claim 1, wherein the side-viewing optics comprise:

at least two side-viewing optical assemblies, each having a different radial field of view.

10. The catheter of claim 9, wherein each side-viewing optical assembly is associated with at least one optical fiber that longitudinally spans the body of the catheter from its proximal end to the side-viewing optical assembly so that light transmitted from the proximal end of the catheter can be directed to a blood vessel wall and light received from a blood vessel wall can be transmitted out of the catheter for analysis.

11. The catheter of claim 9, wherein the side-viewing optics comprise:

four side-viewing optical assemblies, each radially separated from adjacent assemblies by 90-deg or approximately 90-deg and each having an at least substantially non-overlapping radial field of view with the other.

12. The catheter of claim 11, wherein each side-viewing optical assembly is associated with at least one optical fiber that longitudinally spans the body of the catheter from its proximal end to the side-viewing optical assembly so that light transmitted from the proximal end of the catheter can be directed to a blood vessel wall and light received from a blood vessel wall can be transmitted out of the catheter for analysis.