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Instantaneous Autonomic Nervous Function and Cardiac Predictability Based on Heart and Pulse Rate Variability Analysis

  • US 20070219455A1
  • Filed: 03/26/2004
  • Published: 09/20/2007
  • Est. Priority Date: 03/26/2003
  • Status: Active Grant
First Claim
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1. A method of determining the details of dynamic autonomic nervous system function from the measured variability of heart activity occurring during a time period approximating the inverse of the lowest frequency component of the heart rate variability chosen for analysis, comprising the steps of:

  • sequentially receiving data points of heart activity data over a period of time corresponding to the said time period of the heart activity;

    evaluating said data points as sequentially received to determine QRS events;

    outputting said QRS events to a processor as they are sequentially determined;

    processing said output QRS events using time-frequency, nonlinear, nonstationary analysis methods as they are output to periodically determine autonomic nervous system information, wherein said autonomic nervous system information is based on a selected number of output QRS events corresponding to the said selected time period; and

    periodically redetermining said autonomic nervous system information using at least some subsequently output QRS events; and

    during said period of time corresponding to the time period of the heart activity, displaying the most recently determined autonomic nervous system information.

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