DEVICES AND METHODS FOR TARGETED NASAL PHOTOTHERAPY

• US 20070219600A1
• Filed: 08/24/2006
• Published: 09/20/2007
• Est. Priority Date: 03/17/2006
• Status: Abandoned Application

• Current Assignee: Allux Medical, Inc.
• Original Assignee: Allux Medical, Inc.
• Inventors: Johnson, Peter L., Gertner, Michael, Flom, James R., Rogers, Erica, Leclerc, Norbert H.
• Application Number:
  US11/467,131
• Publication Number:
  US 20070219600A1
• Time in Patent Office: Days
• US Class Current: 607/88
• CPC Class Codes: A61N 2005/0607 Nose
• CPC Class Codes: A61N 2005/063 comprising light transmitting means, e.g. optical fibres
• CPC Class Codes: A61N 2005/0644 Handheld applicators
• CPC Class Codes: A61N 2005/0647 the applicator adapted to be worn on the head
• CPC Class Codes: A61N 2005/0652 Arrays of diodes
• CPC Class Codes: A61N 2005/0654 Lamps
• CPC Class Codes: A61N 2005/0661 ultraviolet
• CPC Class Codes: A61N 5/0603 for treatment of body cavities

Abstract

The invention is directed to therapy devices for providing therapeutic light to a target region of tissue within a nasal cavity. The devices are adapted to include a light source communicating with a distal end of the first insertion member, wherein light from the light source illuminates a target region of tissue within a nasal cavity posterior to a limen nasi of the nasal cavity, and further wherein the insertion member is configured to prevent illumination of a region of tissue anterior to the limen nasi. The devices are further adapted to be positioned within the nasal cavity by a user without observing the location of the distal tip.

Claims

1. An optical therapy device for providing therapeutic light to a target region of tissue within a nasal cavity, comprising:

a first insertion member;

a light source communicating with a distal end of the first insertion member, wherein light from the light source illuminates a target region of tissue within a nasal cavity posterior a to limen nasi of the nasal cavity, and further wherein the insertion member is configured to prevent illumination of a region of tissue anterior to the limen nasi.

2. The device of claim 1 wherein the insertion member comprises a light conditioner configured to condition light exiting the distal end.

3. The device of claim 2 wherein the light conditioner is selected from the group consisting of:

light scattering particles, a lens, a mirror, a filter, and a diffuser.

4. The device of claim 1 wherein the insertion member comprises an expandable component configured for positioning in a space between a nasal septum and a lateral wall of the nasal cavity.

5. The device of claim 4 wherein the expandable component transmits light.

6. The device of claim 1 wherein at least a portion of the insertion member comprises a soft material.

7. The device of claim 6 wherein the soft material is selected from the group consisting of:

an elastomer, a rubber, a polymer, a hydrogel, a viscoelastic material, a hydrophilic material, and a hydrophobic material.

8. The device of claim 1 wherein the insertion member is further configured to provide a nasal anatomy information to an operator.

9. The device of claim 1 wherein the insertion member is further configured to transmit imaging information to an operator.

10. The device of claim 1 wherein the insertion member further comprises a depth gauge to set a depth of light delivery.

11. The device of claim 1 wherein the insertion member comprises a ruler.

12. The device of claim 1 wherein the insertion member comprises a first insertion member, the optical therapy device further comprising a second insertion member engaging the first insertion member.

13. The device of claim 12 wherein the second insertion member is configured to adjust the depth of the first insertion member.

14. The device of claim 12 wherein the second insertion member is positionable relative to a nasal bridge.

15. The device of claim 1 wherein the insertion member comprises a separable component adapted and configured to be positioned between a lateral wall of a nasal cavity and the nasal septum and a second component which fits onto the optical therapy device and which is adapted to dock in the separable component.

16. The device of claim 15 where the separable component is configured to position a depth of the second component within the nasal cavity.

17. The device of claim 15 wherein the separable component is configured to determine an angle at which the second component directs the optical therapy device.

18. The device of claim 1 wherein the insertion member has one or more stackable elements configured to position a depth of the distal end within the nasal cavity.

19. The device of claim 1 further comprising a securement device adapted to engage a patient.

20. The device of claim 19 wherein the securement device is adapted to position the insertion member in the nasal cavity.

21. An optical therapy device for providing therapeutic light to a nasal cavity, comprising:

one or more light sources; and

an insertion member adapted to deliver therapeutic light from a light source to a first region of the nasal cavity while preventing light delivery to a second region, wherein the insertion member is further adapted to be positioned within the nasal cavity without visualization of the nasal cavity by an operator.

22. The optical therapy device of claim 21 wherein the first region comprises respiratory epithelium and the second region is the squamous epithelium of the nasal vestibule.

23. The optical therapy device of claim 21 wherein the second region is one or more regions selected from the group consisting of a nasal vestibule, nasal septum, and a nasal valve.

24. The optical therapy device of claim 21 wherein the insertion member comprises a light conditioner further configured to condition light exiting a light exit region.

25. The optical therapy device of claim 21 wherein the insertion member further comprises an expandable component adapted to expand a space between a nasal septum and a lateral wall of the nasal cavity.

26. The optical therapy device of claim 21 wherein the insertion member is further adapted to partially block light from the light emitters.

27. The optical therapy device of claim 21 wherein the insertion member comprises of a first part adapted and configured to expand a region between a lateral wall of a nasal cavity and the nasal septum and a second part having an optical therapy device adapted to dock in the first part.

28. An optical therapy device for providing therapeutic light to a nasal cavity, comprising:

an insertion member having a sensor adapted to provide nasal structure feedback to an operator; and

one or more light sources adapted to illuminate the nasal cavity.

29. The optical therapy device of claim 28 wherein the feedback is visual information from an imaging element associated with the device.

30. The optical therapy device of claim 29 wherein the visual information is obtained by way of a semiconductor imaging element.

31. A method of applying phototherapy to a target region of a nasal cavity comprising:

(a) inserting a device having an insertion member into the nasal cavity;

(b) positioning the insertion member at or near a target region; and

(c) selectively delivering phototherapy to the target region of the nasal cavity.

32. The method of claim 31 wherein the insertion member is adapted to transmit target region information to an operator of the device regarding the target regions of the nasal cavity.

33. The method of claim 32 wherein the target region information is visual.

34. The method of claim 32 wherein the target region information is anatomic measurements.

35. The method of claim 31 further comprising the step of wedging open the limen nasi.

36. The method of claim 31 further comprising adjusting a depth at which the distal tip of the insertion member emits light.

37. The method of claim 31 wherein the step of inserting a device further comprises the step of adjusting a distance between a base of a first insertion member and a base of a second insertion member.

38. The method of claim 31 wherein the step of inserting a device further comprises the step of adjusting an angle between an axis of a first insertion member and an axis of a second insertion member.

39. The method of claim 31 wherein the step of inserting a device further comprises the step of positioning an external depth gauge adjacent a target anatomical location.

40. The method of claim 31 wherein the step of inserting a device further comprises the step of positioning a removable insertion guide over the insertion member prior to inserting the insertion member into the nasal cavity.

41. The method of claim 31 wherein the step of inserting a device further comprises the step of positioning a cap in the nasal cavity prior to a step of docking the insertion member into the cap.

42. The method of claim 31 further comprising the step of securing the insertion member to a patient.

43. The method of claim 31 further comprising the step of conditioning the phototherapy prior to delivery to the target region of the nasal cavity.

44. The method of claim 31 further comprising the step of measuring an anatomy of the nasal cavity.

45. An optical therapy device for providing therapeutic light to a nasal cavity, comprising:

an insertion member configured to pivot relative to a connector positioned external a nasal cavity of a patient; and

one or more light sources adapted to illuminate the nasal cavity.

46. The optical therapy device of claim 45 comprising a second insertion member configured to pivot relative to the connector.

47. The optical therapy device of claim 46 further comprising a bridge between the first and second insertion members.

48. The optical therapy device of claim 47 wherein the first or second insertion member slideably engages the bridge.

49. The optical therapy device of claim 45 wherein the insertion member pivots a distal end of the insertion member relative to the connector.