Metabolic measurements system including a multiple function airway adapter
First Claim
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1. A metabolic measurement system comprising:
- (a) an airway adapter adapted to be coupled in series with a mainstream gas flow comprising;
(1) a housing have a bore defined therethrough to carry the mainstream gas flow through the airway adapter, (2) a window defined in the housing providing optical access to the gas flow through the airway adapter, and (3) an opening defined in the housing providing optical access to the gas flow through the airway adapter;
(b) a sensor head to be removably attached to the airway adapter, the sensor head comprising;
(1) an infrared sensing system adapted to transmit or receive infrared through the window, and (2) a luminescence quenching system adapted to (i) transmit excitation radiation through the opening, (ii) receive emitted radiation from a luminescence material through the opening, or both (i) and (ii);
(c) a flow measurement system adapted to be coupled in series with such a mainstream gas flow; and
(d) a processor adapted to receive signals from the infrared sensing system, the luminescence quenching system, and the flow measurement system, wherein the processor is adapted to determine a metabolic parameter including oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory quotient (RQ), resting energy expenditure (REE), or any combination thereof.
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Abstract
A system for measuring a metabolic parameter. The system includes an integrated airway adapter capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.
149 Citations
30 Claims
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1. A metabolic measurement system comprising:
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(a) an airway adapter adapted to be coupled in series with a mainstream gas flow comprising;
(1) a housing have a bore defined therethrough to carry the mainstream gas flow through the airway adapter, (2) a window defined in the housing providing optical access to the gas flow through the airway adapter, and (3) an opening defined in the housing providing optical access to the gas flow through the airway adapter;
(b) a sensor head to be removably attached to the airway adapter, the sensor head comprising;
(1) an infrared sensing system adapted to transmit or receive infrared through the window, and (2) a luminescence quenching system adapted to (i) transmit excitation radiation through the opening, (ii) receive emitted radiation from a luminescence material through the opening, or both (i) and (ii);
(c) a flow measurement system adapted to be coupled in series with such a mainstream gas flow; and
(d) a processor adapted to receive signals from the infrared sensing system, the luminescence quenching system, and the flow measurement system, wherein the processor is adapted to determine a metabolic parameter including oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory quotient (RQ), resting energy expenditure (REE), or any combination thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A metabolic measurement system comprising:
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(a) an airway adapter adapted to be coupled in series with a mainstream gas flow comprising;
(1) a housing have a bore defined therethrough to carry the mainstream gas flow through the airway adapter, (2) a window defined in the housing providing optical access to the gas flow through the airway adapter, and (3) an opening defined in the housing providing optical access to the gas flow through the airway adapter;
(b) a sensor head to be removably attached to the airway adapter, the sensor head comprising;
(1) an infrared sensing system adapted to transmit or receive infrared through the window, and (2) an oxygen sensing system associated with the opening and adapted to provide a signal indicative of a concentration of oxygen in the gas flow;
(c) a flow measurement system adapted to be coupled in series with such a mainstream gas flow; and
(d) a processor adapted to receive signals from the infrared sensing system, the luminescence quenching system, and the flow measurement system, wherein the processor is adapted to determine a metabolic parameter including oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory quotient (RQ), resting energy expenditure (REE), or any combination thereof. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30)
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Specification