Apparatus and methods for cardiac ablation

• US 20070225697A1
• Filed: 03/23/2006
• Published: 09/27/2007
• Est. Priority Date: 03/23/2006
• Status: Abandoned Application

• Current Assignee: Maquet Cardiovascular LLC (Getinge AB)
• Original Assignee: Maquet Cardiovascular LLC (Getinge AB)
• Inventors: Morin, Patrick, Shroff, Ketan, Agarwal, Amit, Chin, Sing
• Application Number:
  US11/388,108
• Publication Number:
  US 20070225697A1
• Time in Patent Office: Days
• US Class Current: 606/33
• CPC Class Codes: A61B 18/1442 Probes having pivoting end effectors, e.g. forceps
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/2945 Curved jaws
• CPC Class Codes: A61B 2018/00363 Epicardium
• CPC Class Codes: A61B 2018/00375 Ostium, e.g. ostium of pulmonary vein or artery
• CPC Class Codes: A61B 2018/00809 measured thermochromatically
• CPC Class Codes: A61B 2018/1432 curved

Abstract

An adjustable surgical clamp including one or more ablation elements creates a circular lesion in a first operating mode and a linear lesion in a second operating mode. A “box” lesion surrounding all four pulmonary veins may be formed by using the clamp to create two complimentary C-shaped lesions about pairs of the veins. A thermochromic liquid crystal strip that changes color at a tissue-ablating threshold temperature may be mounted on the surgical clamp to monitor temperature of the ablated tissue. Two microwave antennae may be positioned on the jaws of the clamp relative to each other to produce a combined substantially uniform field of tissue-ablating energy between the jaws.

Claims

1. A surgical clamp having a proximal end for forming a cardiac lesion, the clamp comprising:

a first jaw including a first tissue-ablating element disposed to selectively ablate tissue in proximity thereto; and

a second jaw detachably coupled to the first jaw at a location near a proximal end of the first jaw and adjustable in distance therefrom.

2. The surgical clamp of claim 1 wherein:

the second jaw includes a second tissue-ablating element disposed to selectively ablate tissue in proximity thereto;

the first and second jaws being configurable to compress a tissue structure therebetween in a closed position, and to ablate tissue adjacent to the tissue-ablating elements responsive to the application of ablating energy to selected ones of the first and second tissue-ablating elements; and

the first tissue-ablating element in the first jaw being operable independently of the second tissue-ablating element in the second jaw to form a linear lesion in tissue adjacent thereto responsive to the application of ablating energy to the first tissue-ablating element.

3. The surgical clamp of claim 1 further including:

a spring disposed between the first and second jaws and configured to compress responsive to a decrease in the distance therebetween for resiliently biasing the first and second jaws toward spaced-apart orientations.

4. The surgical clamp of claim 1 further including an attachment portion located near the proximal ends of the jaws for attachment of the clamp to a distal end of a support structure for positioning the clamp with respect to a surgical site.

5. The surgical clamp of claim 1 in which the distance between the first and second jaws is adjustable.

6. The surgical clamp of claim 4 in which the attachment portion is disposed to detach the second jaw from the clamp.

7. The surgical clamp of claim 4 wherein the support structure comprises:

a flexible elongated body extending between a proximal portion and a distal portion that is coupled to the clamp; and

a manual controller mounted to the elongated body for selectively inhibiting flexible movement of the elongated body.

8. The surgical clamp of claim 7 wherein the manual controller comprises a rotatable knob mounted adjacent to the proximal portion of the elongated body and linked to a tensioning member disposed within the elongated body for manually tensioning the tension member to inhibit flexible movement of the elongated body.

9. The surgical clamp of claim 4 wherein the support structure comprises a clamp control element mounted near the proximal end for implementing one of:

positioning the clamp in relationship to a surgical site, adjusting a distance between the two jaws of the clamp, and detaching the second jaw from the clamp.

10. The surgical clamp of claim 1 further comprising a sensor disposed in one of the first and second jaws for sensing a characteristic of tissue adjacent thereto.

11. The surgical clamp of claim 10 wherein the sensor is positioned in one of the first and second jaws to sense ablation of tissue in response to tissue-ablating energy applied thereto from the other of the first and second jaws.

12. The surgical clamp of claim 10 wherein the sensor is configured to change color responsive to attainment of an elevated temperature by tissue located adjacent thereto.

13. The surgical clamp of claim 12 wherein the sensor is configured to change color irreversibly responsive to attainment of a selected elevated temperature.

14. The surgical clamp of claim 10 wherein the sensor is responsive to one of the characteristics of:

the color of tissue, the impedence of tissue, and the power transmitted through tissue.

15. The surgical clamp of claim 10 wherein:

one of the tissue-ablating elements operates in an ablation mode for delivering ablation energy from an energy source to tissue adjacent to the element, and operates in a sensing mode for monitoring a selected characteristic of ablated tissue adjacent to the one of the tissue-ablating elements.

16. The surgical clamp of claim 15 including circuitry configured to alternate between the ablation mode and the sensing mode for ablating and monitoring tissue.

17. The surgical clamp of claim 1 wherein:

the first tissue-ablating element comprises a first microwave antenna disposed to produce a first electromagnetic field upon energization thereof; and

the second jaw comprises a second microwave antenna positioned to produce a second electromagnetic field substantially complementary to the first electromagnetic field upon energization thereof.

18. A surgical procedure for forming a lesion on a patient'"'"'s heart using a surgical clamp including two jaws, each jaw including an ablative element disposed along the length of the jaw, the procedure comprising:

forming an incision;

advancing the surgical clamp through the incision toward a surgical site;

positioning the surgical clamp adjacent to a portion of the patient'"'"'s left atrium;

enclosing between the pair of jaws a portion of the ostia of a first pair of the patient'"'"'s pulmonary veins;

closing the jaws of the clamp and applying ablative energy to each of the ablative elements to form a first substantially continuous lesion;

repositioning the clamp to enclose between the pair of jaws the ostia of a second pair of the patient'"'"'s pulmonary veins

closing the clamp and applying ablative energy to each of the ablative elements to form a second substantially continuous lesion; and

forming at least one intermediate lesion between the substantially continuous first lesion and the second substantially continuous lesion surrounding a plurality of the patient'"'"'s pulmonary veins.

19. The surgical procedure of claim 18, wherein the at least one intermediate lesion is formed by the clamp.

20. A surgical procedure for forming a plurality of lesions on a patient'"'"'s heart using a single surgical clamp including a first and second jaw, each jaw including an ablative element disposed along the length of the jaw, the procedure comprising:

forming an incision;

advancing the surgical clamp through the incision toward a surgical site;

positioning the surgical clamp on a first portion of tissue at the surgical site;

enclosing the first portion of tissue between the jaws;

closing the jaws and applying ablative energy to each of the ablative elements to form a substantially continuous lesion in the enclosed portion of tissue;

configuring the second jaw away from the first jaw to facilitate operation of the first jaw independent of the second jaw on a second portion of tissue at the surgical site;

positioning the first jaw on the second portion of tissue; and

forming a linear lesion on the second portion of tissue responsive to the application of ablative energy to the ablative element included in the first jaw.

21. The procedure of claim 20, wherein configuring comprises one of detaching the second jaw and adjusting the second jaw away from the first jaw.

22. The surgical procedure of claim 20, wherein one of the first and second substantially continuous lesions is formed substantially C-shaped.

23. The surgical procedure of claim 20 further comprising monitoring a selected parameter of the ablated tissue.

24. The surgical procedure of claim 23, wherein monitoring includes observing a change in one of:

the temperature of tissue, an electrical property of tissue, and the color of tissue.

25. An ablation apparatus comprising:

a first elongated microwave antenna for forming a first electromagnetic field along the length thereof;

a second elongated microwave antenna for forming a second electromagnetic field along the length thereof; and

an element supporting the first and the second antennae relative to each other to produce a substantially uniform combined tissue-ablating field along the lengths thereof responsive to energization thereof.

26. The ablation apparatus of claim 25 wherein:

the first and second antennae are adjacently positioned lengthwise to each other; and

responsive to energization of the antennae, a majority of the tissue-ablating energy is directed between the antennae to form a substantially uniform tissue-ablating field along and between the lengths of the antennae.

27. The ablation apparatus of claim 25, wherein:

the first and the second antennae are disposed to produce substantially similar electromagnetic fields of tissue-ablating energy; and

the antennae are oppositely oriented relative to each other.

28. The ablation apparatus of claim 25, wherein:

the first and the second antennae are spaced apart and are disposed to produce substantially complementary electromagnetic fields of tissue-ablating energy between and along the lengths of the first and second antennae.

29. The ablation apparatus of claim 25, further comprising:

a sensor disposed for sensing a change in a selected characteristic of tissue adjacent to an antenna.

30. The ablation apparatus of claim 29 wherein the sensor senses a characteristic of tissue selected from the group consisting of:

the color of tissue, the temperature of tissue, and an electrical parameter of tissue.

31. The ablation apparatus of claim 29, wherein:

a selected one of first and second microwave antenna operates in a first mode for delivering energy through the antenna to tissue adjacent thereto, and operates in a second mode for monitoring the selected characteristic through said one microwave antenna.

32. The ablation apparatus of claim 29, further comprising:

a switch positioned between the selected one of first and second antennae and an energy source for selectively alternating between the first and second mode.

33. The ablation apparatus of claim 31 configured to operate alternately in the first and second modes during the ablation of tissue for assessing ablation thereof.

34. A surgical clamp for forming a cardiac lesion, the clamp comprising:

first and second jaws, each including a tissue-ablating element positionable at a surgical site and disposed to selectively ablate adjacent tissue;

an attachment portion supporting the first and second jaws in clamping configuration and dispose to selectively displace the second jaw from the clamping configuration for isolating the first jaws to ablate tissue adjacent thereto.

35. The surgical clamp as in claim 34, wherein the clamp is operable in a clamp ablation mode with the two jaws disposed to confine for forming a lesion therein in response to applied tissue-ablating energy;

and in a linear ablation mode the first jaw isolated from the second jaw and operable to form a linear lesion on tissue adjacent thereto in response to applied tissue-ablating energy.

36. The surgical clamp as in claim 35, in which the isolation is performed selectively by one of:

detaching the second jaw from the clamp; and

positioning the second jaw substantially away from the first jaw.