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Monte Carlo based model of fluorescence in turbid media and methods and systems for using same to determine intrinsic fluorescence of turbid media

  • US 20070232932A1
  • Filed: 03/16/2007
  • Published: 10/04/2007
  • Est. Priority Date: 03/17/2006
  • Status: Active Grant
First Claim
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1. A method for modeling fluorescence of a turbid medium and for using the model to determine intrinsic fluorescence in the turbid medium, the method comprising:

  • illuminating a turbid medium of interest with an electromagnetic radiation source using a probe of a particular geometry and detecting measured fluorescence for the turbid medium using the probe;

    running at least one set of Monte Carlo simulations to determine an escape energy probability map and an absorbed energy density map for the turbid medium; and

    determining, in a manner that accounts for the geometry of the probe, and using the measured fluorescence, the absorbed energy density map, and the escape energy probability map, an indication of intrinsic fluorescence of the turbid medium.

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