ELECTROCHEMICAL SENSOR STRIP AND MANUFACTURING METHOD THEREOF

• US 20070235330A1
• Filed: 04/09/2007
• Published: 10/11/2007
• Est. Priority Date: 04/11/2006
• Status: Abandoned Application

• Current Assignee: Bionime Corporation, Zensor Corp.
• Original Assignee: Bionime Corporation, Zensor Corp.
• Inventors: Lyuu, Hueih-Jing
• Application Number:
  US11/697,936
• Publication Number:
  US 20070235330A1
• Time in Patent Office: Days
• US Class Current: 204/403.10
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: C12Q 1/002 Electrode membranes
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 33/5438 Electrodes

Abstract

An electrochemical sensor strip is provided. The electrochemical sensor strip includes an insulation substrate, a conduction film, an insulation layer, wherein the conduction film is mounted on the insulation substrate and has a first and a second ends, and the insulation layer is mounted on the conduction film to cover the first end. The second end serves as a signal output terminal, the first end has a first conduction section exposed between the insulation layer and the insulation substrate, and the conduction section serves as a working surface of an electrode of the electrochemical sensor strip.

Claims

1. An electrochemical sensor strip, comprising:

an insulation substrate;

a first conduction film mounted on the insulation substrate and having a first and a second ends; and

an insulation layer mounted on the first conduction film to cover the first end,

wherein the second end serves as a signal output terminal, the first end has a first conduction section exposed between the insulation layer and the insulation substrate, and the first conduction section serves as a working surface of an electrode of the electrochemical sensor strip.

2. An electrochemical sensor strip according to claim 1, wherein the insulation layer is an insulation thin layer entirely covering the first end, the insulation layer is mounted on a first surface of the conduction film, the second end is a preserved conduction area not being covered by the insulation layer for serving as the signal output terminal, and the exposed first conduction section is a transverse cross section of the first conduction film.

3. An electrochemical sensor strip according to claim 2, wherein the first conduction film is mounted on the insulation substrate by one selected from a group consisting of a printing, an evaporation, an electroplating and an adhering.

4. An electrochemical sensor strip according to claim 2 further comprising a second conduction film having a second conduction section exposed between the insulation layer and the insulation substrate, wherein the second conduction section serves as the working surface of the electrode of the electrochemical sensor strip with the first conduction section.

5. An electrochemical sensor strip according to claim 4 having an opening, further comprising:

a insulation piece mounted on the opening to form a fluid receiving portion for the strip; and

a chemical agent mounted on the fluid receiving portion for chemically reacting with a sample to be tested,

wherein the insulation substrate and the insulation film are respectively a non-conductive substrate and a disk-like film, the first and the second conduction films are arranged radiately from the opening by being adhered onto the non-conductive substrate, and an electrical signal generated from the chemical reaction is output from the electrode.

6. An electrochemical sensor strip according to claim 5, wherein the chemical agent is one selected from a group consisting of an enzyme, an antibody, an electrolyte, a thickening agent, a water and a protecting agent for a biological compound.

7. An electrochemical sensor strip according to claim 1 further comprising a second and a third conduction films respectively having a second and a third conduction sections exposed between the insulation layer and the insulation substrate, wherein the insulation substrate is a high molecular weight polymer being one of a thermo plastic and a thermoset plastic.

8. An electrochemical sensor strip according to claim 1 further comprising a second conduction film and another insulation layer, wherein the second conduction film has a second conduction section exposed between the another insulation layer and the insulation substrate, and at least one of the insulation layers and the insulation substrate is a high molecular weight polymer being one of a thermo plastic and a thermoset plastic.

9. An electrochemical sensor strip according to claim 1, wherein the first conduction section is obtained by one selected from a group consisting of a cutting, a stamping, a drilling, a water cutting, a laser cutting, a chemical etching, an optical lithography, a chemical dissolution, and a heat-melting process, and the electrode being processed is an ultramicroelectrode.

10. An electrochemical sensor strip according to claim 1, wherein the first conduction film is made of one selected from a group consisting of a metal, an oxide thereof, a complex thereof, and an alloy thereof, and the electrode is one selected from a group consisting of a working electrode, an auxiliary electrode, and a reference electrode.

11. An electrochemical sensor strip according to claim 10, wherein the metal is one selected from a group consisting of a carbon, a copper, a silver, a gold, a rhodium, a ruthenium, a manganese, an iron, a platinum, an osmium, a nickel, a cobalt, a mercury, an iridium, and a bismuth.

12. An electrochemical sensor strip according to claim 1 further comprising:

a second conduction film mounted on the insulation substrate and having a third and a fourth ends; and

another insulation layer mounted on the second conduction film,

wherein the first and the second conduction films are mounted on a first and a second surfaces of the insulation substrate respectively, the fourth end serves as another signal output terminal, the third end has a second conduction section exposed between the another insulation layer and the insulation substrate for serving as the working surface of the electrode of the electrochemical sensor strip with the first conduction section.

13. An electrochemical sensor strip according to claim 1 further comprising:

another insulation substrate; and

a second conduction film mounted on the another insulation substrate and having a third and a fourth ends,

wherein the insulation substrate is mounted on the second conduction film, the fourth end serves as another signal output terminal, the third end has a second conduction section exposed between the insulation substrates, and the second conduction section serves as the working surface of the electrode of the electrochemical sensor strip with the first conduction section.

14. An electrochemical sensor strip according to claim 13 further comprising:

a third conduction film mounted between the insulation substrate and the insulation layer and having a third conduction section exposed therebetween.

15. An electrochemical sensor strip according to claim 13 further comprising:

a third conduction film mounted between the insulation substrates and having a third conduction section exposed therebetween.

16. An electrochemical sensor strip according to claim 1 further comprising:

a second conduction film mounted between the insulation substrate and the insulation layer and having a third and a fourth ends;

another insulation substrate mounted on the insulation layer; and

a piece mounted on the insulation substrate,

wherein the fourth ends serves as another signal output terminal, the third end has a second conduction section exposed between the insulation substrate and the insulation layer with the second conduction section serving as the working surface of the electrode of the electrochemical sensor strip with the first conduction section, the strip has an opening between the first and the second conduction sections, and the opening, the first and the second conduction sections are mounted between the piece and the another insulation substrate.

17. An electrochemical sensor strip according to claim 14, wherein the insulation substrate and the insulation layer respectively have a first slot and an insulation slot for forming the opening, and a fluid receiving portion is defined by the opening, the insulation substrate and the insulation layer for receiving a sample.

18. An electrochemical sensor strip, comprising:

a conduction film having a first and a second ends and a first and a second surfaces;

a first insulation layer mounted on the first surface of the conduction film; and

a second insulation layer mounted on the second surface of the conduction film,

wherein the second end serves as a signal output terminal, and the first end is mounted between the first and the second insulation layers for serving as a working surface of an electrode of the electrochemical sensor strip.

20. A method according to claim 18, wherein the separating step is performed by one selected from a group consisting of a cutting, a stamping, a drilling, a water cutting, a laser cutting, a chemical etching, an optical lithography, a chemical dissolution, and a heat-melting process.

19. A method for manufacturing an electrochemical sensor strip, comprising steps of:

providing an insulation piece;

mounting a first conduction film having a first and a second ends on the insulation piece;

partially mounting an insulation layer on the first conduction film for covering the first end and forming the second end as a first signal output terminal; and

respectively separating a part of the first end and a part of the insulation layer covering thereon from the first end and the insulation layer for obtaining a first conduction section.

21. An electrochemical sensor strip, comprising:

a conduction film having a first and a second surfaces;

a first insulation layer partially mounted on the first surface of the conduction film; and

a second insulation layer mounted on the second surface of the conduction film;

wherein a first portion of the conduction film mounted between the first and the second insulation layers serves as a working surface of an electrode of the electrochemical sensor strip.

22. An electrochemical sensor strip as claimed in claim 21, wherein a second portion of the conduction film mounted on the second insulation layer and not covered by the first insulation layer serves as a signal output terminal of the electrochemical sensor strip.