Electrophoresis cassette with collapsible buffer chamber

• US 20070235337A1
• Filed: 04/07/2006
• Published: 10/11/2007
• Est. Priority Date: 04/07/2006
• Status: Active Grant

• Current Assignee: Bio-Rad Laboratories Incorporated
• Original Assignee: Bio-Rad Laboratories Incorporated
• Inventors: Gueffroy, Donald
• Granted Patent: US 7,754,060 B2
• Time in Patent Office: Days
• US Class Current: 204/606
• CPC Class Codes: G01N 27/447 using electrophoresis

Abstract

A slab gel electrophoresis cassette with an integrated upper buffer chamber is constructed such that the integrated chamber is collapsible to allow the cassette to assume a reduced thickness for purposes of stacking during storage and shipping.

Claims

1. In a slab gel cassette for vertical slab gel electrophoresis comprising first and second plates and spacing means therebetween to define a slab-shaped space, said first plate further comprising a protruding portion along one edge of said first plate, defined as an upper edge, to form a liquid reservoir above said slab-shaped space, said reservoir being of expanded depth relative to said slab-shaped space for use as an upper buffer chamber, the improvement in which said liquid reservoir is collapsible to reduce the depth of said reservoir when not in use.

2. The slab gel cassette of claim 1 wherein said protruding portion of said first plate comprises a planar wall segment joined to the remainder of said first plate by side walls and a base wall, and said side walls and base wall are each formed with at least one pleat that can be opened and closed.

3. The slab gel cassette of claim 2 wherein said side walls and base wall are each formed with a plurality of pleats that can be opened and closed.

4. The slab gel cassette of claim 1 wherein said liquid reservoir is collapsible when compressed by an external force and resilient to return to an expanded condition upon release from said external force.

5. The slab gel cassette of claim 1 wherein said protruding portion is formed of an elastomer.

6. The slab gel cassette of claim 1 wherein said protruding portion is formed of an elastomer selected from the group consisting of polyethylenes, polypropylenes, and nylons.