Embolic prosthesis for treatment of vascular aneurysm

• US 20070237720A1
• Filed: 04/06/2006
• Published: 10/11/2007
• Est. Priority Date: 04/06/2006
• Status: Abandoned Application

• Current Assignee: REVA Medical Inc.
• Original Assignee: REVA Medical Inc.
• Inventors: Schmid, Eric V., Nguyen, John, Padilla, Orlando, Morris, Andrew, McGrath, James E., Brandom, Donald K.
• Application Number:
  US11/399,136
• Publication Number:
  US 20070237720A1
• Time in Patent Office: Days
• US Class Current: 424/9.410
• CPC Class Codes: A61B 17/0467 Instruments for cutting sutures surgical cutting instruments A61B17/32
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12081 detachable by inflation
• CPC Class Codes: A61B 2090/037 with a frangible part, e.g. by reduced diameter
• CPC Class Codes: A61K 49/0442 Polymeric X-ray contrast-enhancing agent comprising a halogenated group
• CPC Class Codes: A61L 24/001 Use of materials characterised by their function or physical properties
• CPC Class Codes: A61L 24/0042 Materials resorbable by the body
• CPC Class Codes: A61L 24/06 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L24/043, A61L24/046 take precedence
• CPC Class Codes: A61L 2430/36 for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Abstract

The invention relates to an implantable embolic medical device comprising a non-erodible, erodible or biodegradable material. The device preferably comprises one or more longitudinal filament members of varying cross sectional shapes which may or may not be coiled to suit a particular clinical need. The embolic device is placed through lumens and cavities to reach areas in the body which require embolism to achieve a particular clinical objective.

Claims

1. An embolic filament, comprising a bioresorbable radiopaque material, wherein said filament is configured for occluding a lumen or cavity in need thereof.

2. The embolic filament of claim 1, wherein said material comprises a polymer.

3. The embolic filament of claim 1, wherein said material comprises a radiopaque polymer.

4. The embolic filament of claim 3, wherein said radiopaque polymer is selected from formulae I-XV.

5. The embolic filament of claim 3, wherein said material comprises an erodible or corrodible metal.

6. The embolic filament of claim 1, further comprising notches configured to facilitate detachment of the filament.

7. A device for deploying an embolic filament to an aneurysm, comprising a guiding catheter with a lumen adapted for endoluminal catheterization of the aneurysm;

a spooling mechanism comprising a length of the embolic filament of claim 1 wound around a spool;

a filament advancing mechanism adapted to advance the filament distally through the guiding catheter; and

a filament detachment mechanism adapted to sever the advancing filament thereby facilitating filament deployment within the aneurysm.

8. The device of claim 7, further comprising a compliant balloon configured to bridge the aneurysm neck.

9. A method for embolizing a vascular aneurysm, comprising providing the device of claim 7;

catheterizing the aneurysm;

engaging the filament advancing mechanism; and

engaging the filament detachment mechanism.

10. An embolic filament bundle for occluding an aneurysm, comprising a plurality of embolic filaments and a bundled section where the filaments are bundled together at a predetermined location.

11. The embolic filament bundle of claim 10, wherein the bundled section is shaped to facilitate deployment without causing perforation of the aneurysm.

12. A device for deploying the embolic filament bundle of claim 10 to an aneurysm, comprising a guiding catheter with a lumen adapted for endoluminal catheterization of the aneurysm;

and a pushing means for advancing the embolic filament bundle distally through the guiding catheter thereby facilitating embolic filament bundle deployment within the aneurysm.

13. A method for embolizing a vascular aneurysm, comprising providing the device of claim 12;

catheterizing the aneurysm;

loading at least one embolic filament bundle into the device; and

advancing the pushing means thereby deploying the embolic filament bundle.

14. The method of claim 13, wherein the pushing means is a pushing rod.