2-Methylene-1alpha-Hydroxy-18,19,21-Trinorvitamin D3 Analogs and Uses Thereof
First Claim
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1. A compound having the formula I wherein X1 and X2 are independently selected from H and hydroxy protecting groups.
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Accused Products
Abstract
Compounds of formula I are provided where X1 and X2 are independently selected from H or hydroxy protecting groups. Such compounds are used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
39 Citations
27 Claims
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1. A compound having the formula I
wherein X1 and X2 are independently selected from H and hydroxy protecting groups.
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17. A compound having the formula II
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21. A method of treating or preventing obesity of an animal, inhibiting adipocyte differentiation, inhibiting SCD-1 gene transcription, and/or reducing body fat in an animal comprising administering to an animal in need thereof an effective amount of a compound having the formula:
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wherein X1 and X2 are independently selected from H and hydroxy protecting groups. - View Dependent Claims (22, 23, 24, 25, 26, 27)
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25. The method of claim 21 wherein the animal is a human.
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26. The method of claim 21 wherein the animal is a domestic animal
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27. The method of claim 21 wherein the animal is an agricultural animal.
Specification