Method and apparatus for using an optical hemodynamic sensor to identify an unstable arrhythmia

• US 20070239215A1
• Filed: 03/31/2006
• Published: 10/11/2007
• Est. Priority Date: 03/31/2006
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Cinbis, Can, Bhunia, Sourav, Olson, Walter
• Granted Patent: US 7,787,947 B2
• Time in Patent Office: Days
• US Class Current: 607/6
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/36557 controlled by chemical substances in blood
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

A medical device identifies a hemodynamically unstable arrhythmia based upon optical hemodynamic sensor signals. The optical hemodynamic sensor includes a light source for transmitting light corresponding to first and second wavelengths through a blood perfused tissue of a patient and a light detector for generating optical signals corresponding to an intensity of the detected light at the first and second wavelengths. At a low motion period for the patient, optical signals are obtained from the optical hemodynamic sensor and are analyzed to determine a baseline motion level for the patient. Subsequent signals obtained from the optical hemodynamic sensor are compared to the baseline motion levels, with only those signals corresponding to periods where motion does not exceed the baseline level of motion being further analyzed to determine if they are consistent with a hemodynamically unstable arrhythmia.

Claims

1. A medical device comprising:

an optical sensor for transmitting into body tissue of a patient a plurality of optical signals, receiving the plurality of signals as attenuated by transmission through the body tissue, and generating a plurality of corresponding output signals representative of an intensity of the attenuated signals as received; and

a processor for analyzing the output signals over an initial time period to assess a baseline level of motion and analyzing the output signals over a subsequent time period to determine whether a current level of motion exceeds the baseline level of motion.

2. The medical device of claim 1, wherein the processor further analyzes the output signals over the subsequent time period to determine whether the patient is experiencing a hemodynamically unstable arrhythmia.

3. The medical device of claim 2 and further comprising a therapy delivery system for delivering at least one of a cardiac pacing, a cardioversion, or a defibrillation therapy to the patient, wherein the therapy delivery system delivers at least one of the cardiac pacing, the cardioversion, or the defibrillation therapies to the patient if the processor determines that the patient is experiencing a hemodynamically unstable arrhythmia.

4. The medical device of claim 1 and further comprising a sensor for detecting an electrical signal attendant to the depolarization and repolarization of the patient'"'"'s heart, wherein the processor initially analyzes the electrical signal to determine if the patient is experiencing an arrhythmia and, if it is determined that the patient is experiencing an arrhythmia, further analyzes the output signals to determine whether the patient is experiencing a hemodynamically unstable arrhythmia.

5. The medical device of claim 1, wherein the processor determines a motion level for a time period by calculating a plurality of first moving averages for each of the output signals over a relevant time period, a plurality of motion indices indicative of variations of each output signal and the corresponding first moving average, and a plurality of second moving averages for each of the motion indices over the relevant time period.

6. The medical device of claim 1, wherein the optical sensor comprises a first light emitter capable of transmitting a first optical signal characterized by a first wavelength and a second light emitter capable of transmitting a second optical signal characterized by a second wavelength different from the first wavelength.

7. The medical device of claim 6, wherein the first wavelength is in a range of about 550 nanometers to about 750 nanometers and the second wavelength is in a range of about 750 nanometers to about 2.5 micrometers.

8. The medical device of claim 7, wherein the sensor signals comprise a first and a second sensor signal corresponding to an intensity of a respective one the first and the second optical signal as received by the optical hemodynamic sensor, and wherein the processor determines whether the patient is experiencing a hemodynamically unstable arrhythmia by determining if an intensity of the first sensor signal is decreasing and an intensity of the second sensor signal is increasing.

9. The medical device of claim 1, wherein the medical device is an implantable medical device.

10. A medical device comprising:

an optical hemodynamic sensor for producing sensor signals indicative of hemodynamic function of a patient;

a processor for determining from the sensor signals whether the sensor signals are corrupt sensor signals due to patient motion or uncorrupt sensor signals, and for determining whether the patient is experiencing a hemodynamically unstable arrhythmia based upon the uncorrupt sensor signals.

11. The medical device of claim 10 and further comprising a therapy delivery system for delivering at least one of a cardiac pacing, a cardioversion, or a defibrillation therapy to the patient, wherein the therapy delivery system delivers at least one of the cardiac pacing, the cardioversion, or the defibrillation therapies to the patient if the processor determines that the patient is experiencing a hemodynamically unstable arrhythmia.

12. The medical device of claim 10, wherein the optical hemodynamic sensor comprises a light source for emitting light signals corresponding to at least two wavelengths.

13. The medical device of claim 10, wherein the sensor signals correspond to an intensity of light signals corresponding to at least two wavelengths as attenuated by transmission through body tissue, and wherein the processor determines if the patient is experiencing a hemodynamically unstable arrhythmia based upon a slope of each sensor signal.

14. A method for detecting an unstable arrhythmia in a patient, the method comprising:

obtaining sensor signals from an optical hemodynamic sensor, wherein the sensor signals are indicative of a hemodynamic function of the patient;

determining from an initial period of the sensor signals a baseline motion level of the patient;

determining from a subsequent period of the sensor signals a current motion level of the patient; and

analyzing the sensor signals if the current motion level does not exceed the baseline motion level to determine whether the patient is experiencing a hemodynamically unstable arrhythmia.

15. The method of claim 14 and further comprising:

delivering at least one of a cardiac pacing, a cardioversion, or a defibrillation therapy to the patient if it is determined that the patient is experiencing a hemodynamically unstable arrhythmia.

16. The method of claim 14, wherein obtaining sensor signals from the optical hemodynamic sensor comprises:

transmitting into body tissue of the patient a first optical signal characterized by a first wavelength and a second optical signal characterized by a second wavelength different than the first wavelength;

receiving the first and second signals as attenuated by transmission through the body tissue; and

generating a first and a second sensor signal, each of the first and second sensor signals being representative of an intensity of the attenuated signals as received.

17. The method of claim 16, wherein the first wavelength corresponds to red visible light spectrum and the second wavelength corresponds to infrared light.

18. The method of claim 17, wherein analyzing the sensor signals to determine whether the patient is experiencing a hemodynamically unstable arrhythmia comprises:

determining whether an intensity of the first attenuated signal is decreasing; and

determining whether an intensity of the second attenuated signal is increasing.

19. The method of claim 14, wherein determining from the initial period of the sensor signals the baseline motion level of the patient comprises:

determining a plurality of first moving averages for each of the sensor signals over the initial time period;

determining a plurality of motion indices indicative of variations of each sensor signal and the corresponding first moving average; and

determining a plurality of second moving averages for each of the motion indices over the initial time period.

20. The method of claim 14, wherein determining from the subsequent period of the sensor signals the baseline motion level of the patient comprises:

determining a plurality of first moving averages for each of the sensor signals over the subsequent time period;

determining a plurality of motion indices indicative of variations of each sensor signal and its corresponding first moving average; and

determining a plurality of second moving averages for each of the motion indices over the subsequent time period.