Blood Analyte Determinations
First Claim
1. An apparatus for determining an analyte property in blood, comprising:
- a. a brood removal element, adapted to communicate blood with the circulatory system of a patient;
b. an analyte measurement system, adapted to determine a desired property of blood;
c. a sample drive system in fluid communication with the blood removal element and with the analyte measurement system, adapted to receive a blood sample from the blood removal element and transport it to the analyte measurement system.
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Abstract
The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. An apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.
139 Citations
53 Claims
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1. An apparatus for determining an analyte property in blood, comprising:
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a. a brood removal element, adapted to communicate blood with the circulatory system of a patient; b. an analyte measurement system, adapted to determine a desired property of blood; c. a sample drive system in fluid communication with the blood removal element and with the analyte measurement system, adapted to receive a blood sample from the blood removal element and transport it to the analyte measurement system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52)
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53. A blood access system comprising:
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a. a first junction in fluid communication with a catheter; b. a pressure measurement device in fluid communication with a first side of the first junction; c. a first pump having a first side in fluid communication with the first side of the first junction; d. an air detector mounted intermediate the first side to the first junction in fluid communication with the first side of the first pump; e. a second junction having a first side in fluid communication with a second side of the first pump; f. a first valve having a first side in fluid communication with a second side of the second junction; g. a waste channel having a first side in fluid communication with a second side of the first valve; h. a second valve having a first side in fluid communication with a second side of the waste channel; i. a second pump having a first side in fluid communication with a second side of the second valve; j. an analyte sensor having a first side in fluid communication with a second side of the second pump; k. a third junction having a first side in fluid communication with a second side of the analyte sensor; l. a third valve having a first side in fluid communication with a second side of the third junction; m. a fourth valve having a first side in fluid communication with a second side of the third valve; n. a pressure relief valve in fluid communication with the second side of the third valve; o. a pump in fluid communication with the second side of the third valve; p. a fifth valve having a first side in fluid communication with a third side of the third junction and a second side in fluid communication with a second side of the first junction.
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Specification