Silicone Vesicles Containing Actives

• US 20070243241A1
• Filed: 04/19/2005
• Published: 10/18/2007
• Est. Priority Date: 04/20/2004
• Status: Abandoned Application

• Current Assignee: Shaow Lin, Stephanie Postiaux
• Original Assignee: Shaow Lin, Stephanie Postiaux
• Inventors: Lin, Shaow, Postiaux, Stephanie
• Application Number:
  US11/578,541
• Publication Number:
  US 20070243241A1
• Time in Patent Office: Days
• US Class Current: 424/450
• CPC Class Codes: A61K 8/14 Liposomes; Vesicles
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/585 Organosilicon compounds
• CPC Class Codes: A61K 8/671 Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
• CPC Class Codes: A61K 8/894 modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
• CPC Class Codes: A61Q 1/02 Preparations containing skin colorants, e.g. pigments preparations in powder form A61Q1/12
• CPC Class Codes: A61Q 1/06 Lipsticks
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: B01J 13/02 Making microcapsules or microballoons for medical preparations A61K9/50
• CPC Class Codes: B01J 13/12 removing solvent from the wall-forming material solution

Abstract

A process for preparing a vesicle composition based upon mixing an organopolysiloxane having at least one hydrophilic substituent group, a water miscible volatile solvent, and water is disclosed. The vesicle compositions produced by the method are useful in various personal, household, and health care applications.

Claims

1. A process for preparing a vesicle composition comprising;

I) combining,

A) an organopolysiloxane having at least one hydrophilic substituent group,

B) a water miscible volatile solvent,

C) optionally, a silicone or organic oil,

D) a personal care or health care active,

with water to form an aqueous dispersion,

II) mixing the aqueous dispersion to form vesicles,

III) optionally, removing the water miscible volatile solvent from the vesicles.

2. The process of claim 1 wherein the organopolysiloxane is a silicone polyether having the formula:

3. The process of claim 1 wherein the organopolysiloxane is a (AB)_n block silicone polyether having the formula;

—

[R¹(R₂SiO)_x′

(R₂SiR¹O)(C_mH_2mO)_y′

]_n—

where x′ and

y′

are greater than 4, m is from 2 to 4 inclusive, n is greater than 2,

R is independently a monovalent organic group containing 1 to 20 carbons,

R¹ is a divalent hydrocarbon containing 2 to 30 carbons.

4. The process of claim 1 wherein the water miscible volatile solvent is an alcohol.

5. The process of claim 4 wherein the alcohol is ethanol or isopropanol.

6. The process of claim 1 wherein component C) is present and is a volatile methyl siloxane.

7. The process of claim 1 wherein the personal care active is a vitamin.

8. The process of claim 7 wherein the vitamin is Vitamin A palmitate.

9. The process of claim 1 wherein the personal care active is a sunscreen agent.

10. The process of claim 1 wherein the personal care active is a fragrance or perfume.

11. The process of claim 1 wherein the healthcare active is a pharmaceutical drug.

12. A vesicle composition prepared according to the process of claim 1.

13. A personal care product comprising the vesicle composition of claim 12.

14. The personal care product of claim 13 wherein the personal care product is selected from an antiperspirant, deodorant, skin cream, skin care lotion, moisturizer, facial treatment, wrinkle remover, facial cleansers, bath oils, sunscreens, pre-shave, after-shave lotions, liquid soap, shaving soap, shaving lather, hair shampoo, hair conditioner, hair spray, mousse, permanent, hair cuticle coat, make-up, color cosmetic, foundation, blush, lipstick, lip balm, eyeliner, mascara, nail polishes, and powders.