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Genetically Engineered Pyrroloquinoline Quinone Dependent Glucose Dehydrogenase Comprising an Amino Acid Insertion

  • US 20070243566A1
  • Filed: 07/19/2005
  • Published: 10/18/2007
  • Est. Priority Date: 07/20/2004
  • Status: Active Grant
First Claim
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1. A variant of the soluble form of EC 1.1.99.17 also known as PQQ-dependent soluble glucose dehydrogenase (s-GDH) said variant comprising at least one amino acid residue insertion between the amino acid positions corresponding to positions 428 and 429 of the s-GDH wild-type sequence known from A. calcoaceticus (SEQ ID NO:

  • 2) and optionally in addition comprising one or more amino acid substitutions.

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