Treatment of proliferative diseases
First Claim
1. A pharmaceutical composition comprising a compound of the formula I wherein * is ═
- C or ═
O, R1 and R2 independently represent substituted or unsubstituted alkyl, alkenyl, alkynyl, alkylene, alkenylene, alkoxy, alkenyloxy, cycloalkyl, cycloalkenyl, aryl, aryloxy, arylalkoxy, aroyl, heteroaryl, heterocyclic, acyl, acyloxy, sulfonyl, sulfinyl, sulfenyl, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, ureido, cyano, halo, silyl, silyloxy, silythio, carboxyl, carbonyl, carbamoyl, carboxamide, carboxylic ester, phosphono, a substituted or unsubstituted aryl group fused to a cycloalkyl group, or a pharmaceutically acceptable salt thereof, and pharmaceutically acceptable carriers, excipients, and vehicles.
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Accused Products
Abstract
The invention relates generally to compositions comprising malonate compounds, and methods and uses of the compositions in the treatment of proliferative diseases. In particular the invention relates to a pharmaceutical composition comprising a compound of the formula I
24 Citations
20 Claims
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1. A pharmaceutical composition comprising a compound of the formula I
wherein * is ═ - C or ═
O, R1 and R2 independently represent substituted or unsubstituted alkyl, alkenyl, alkynyl, alkylene, alkenylene, alkoxy, alkenyloxy, cycloalkyl, cycloalkenyl, aryl, aryloxy, arylalkoxy, aroyl, heteroaryl, heterocyclic, acyl, acyloxy, sulfonyl, sulfinyl, sulfenyl, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, ureido, cyano, halo, silyl, silyloxy, silythio, carboxyl, carbonyl, carbamoyl, carboxamide, carboxylic ester, phosphono, a substituted or unsubstituted aryl group fused to a cycloalkyl group, or a pharmaceutically acceptable salt thereof, and pharmaceutically acceptable carriers, excipients, and vehicles. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
- C or ═
Specification