MECHANICAL SINGLE DOSE INTRAPULMONARY DRUG DELIVERY DEVICES
First Claim
Patent Images
1. A single dose drug delivery device, comprising:
- a source of stored energy;
a triggering mechanism;
a container forming part of the device and holding a flowable formulation consisting of only a single dose of pharmaceutically active drug;
a mechanism for transferring said stored energy to the container.
1 Assignment
0 Petitions
Accused Products
Abstract
Devices for delivering an aerosolized drug formulation and methods for using such devices are herein provided. Specifically, the invention relates to a drug delivery device that contains a drug formulation and an actuator for aerosolizing the formulation in preparation for drug delivery. The drug delivery devices of the invention are configured for delivering a single dose of an active agent (e.g., a pharmaceutical compound) or a mixture of multiple active agents and may further be configured so as to be hand-held, self-contained, portable and disposable. Methods of treatment and drugs that are suitable for use in the subject devices are also disclosed.
31 Citations
30 Claims
-
1. A single dose drug delivery device, comprising:
-
a source of stored energy;
a triggering mechanism;
a container forming part of the device and holding a flowable formulation consisting of only a single dose of pharmaceutically active drug;
a mechanism for transferring said stored energy to the container. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
-
-
27. An intrapulmonary drug delivery system, comprising a plurality of drug delivery devices, wherein each device comprises:
-
(a) a single dose container, holding a flowable formulation consisting of only a single dose of a pharmaceutically active drug, the container forming an integral part of the device;
(b) a store of energy, configured for aerosolizing the flowable formulation when the energy is released;
(c) an actuator, configured for releasing the store of energy;
(d) a mouthpiece, configured for allowing the passage of an aerosolized formulation to a user; and
(e) a safety mechanism, configured for preventing the unintended actuation of the actuator.
-
-
28. A method of treatment, comprising:
-
(a) removing an intrapulmonary drug delivery device from packaging, wherein said device comprises the following components;
(1) a container forming an integral part of the device, the container holding flowable formulation consisting of only a single dose of a pharmaceutically active drug;
(2) a store of potential energy, configured for aerosolizing the flowable formulation upon release of the energy;
(3) an actuator, configured for releasing the store of energy;
(4) a mouthpiece, configured for allowing the passage of an aerosolized formulation to a user; and
(5) a safety mechanism, configured for preventing the unintended actuation of the device;
(c) disengaging said safety mechanism;
(d) actuating said actuator so as to release the energy and aerosolize the flowable formulation and produce an aerosolized formulation;
(e) inhaling said aerosolized formulation; and
(f) disposing of said intrapulmonary drug delivery device and its packaging. - View Dependent Claims (29, 30)
-
Specification