SYSTEM AND METHOD FOR USING CARDIAC EVENTS TO TRIGGER THERAPY FOR TREATING NERVOUS SYSTEM DISORDERS
First Claim
1. A method of treating a nervous system disorder in a patient, the method comprising:
- sensing a brain signal from the patient;
obtaining a neurological event detection signal, the neurological event detection signal indicating neurological events detected from the brain signal;
sensing a cardiac signal from the patient;
obtaining a cardiac event detection signal, the cardiac event detection signal indicating cardiac events detected from the cardiac signal;
analyzing timing relationships between detected events, the detected events including detected neurological events and detected cardiac events;
identifying a matched event when one of the detected neurological events is temporally related to one of the detected cardiac events;
determining whether the cardiac event detection signal facilitates detection of neurological events based on matched events;
delivering a therapy to the patient for treating the neurological disorder in response to a cardiac event if the cardiac event detection signal is determined to facilitate detection of neurological events; and
changing the therapy delivered to the patient based on the brain signal.
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Abstract
A method of treating a neurological disorder in a patient. In some embodiments, the method includes obtaining a neurological event detection signal, obtaining a cardiac event detection signal, analyzing the timing relationships between the detected neurological and cardiac events to identify matched events, using the matched events to determine whether the cardiac event detection signal facilitates detection of neurological events, delivering a therapy to the patient in response to a cardiac event if the cardiac event detection signal is determined to facilitate detection of neurological events, and changing the therapy delivered based on sensed brain signals from the patient.
215 Citations
78 Claims
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1. A method of treating a nervous system disorder in a patient, the method comprising:
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sensing a brain signal from the patient;
obtaining a neurological event detection signal, the neurological event detection signal indicating neurological events detected from the brain signal;
sensing a cardiac signal from the patient;
obtaining a cardiac event detection signal, the cardiac event detection signal indicating cardiac events detected from the cardiac signal;
analyzing timing relationships between detected events, the detected events including detected neurological events and detected cardiac events;
identifying a matched event when one of the detected neurological events is temporally related to one of the detected cardiac events;
determining whether the cardiac event detection signal facilitates detection of neurological events based on matched events;
delivering a therapy to the patient for treating the neurological disorder in response to a cardiac event if the cardiac event detection signal is determined to facilitate detection of neurological events; and
changing the therapy delivered to the patient based on the brain signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63)
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64. An implantable medical device (IMD) for treating a neurological disorder in a patient, the device comprising:
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a biocompatible housing adapted to be implanted in a patient;
a power source;
a therapy module; and
a processor, the processor being adapted to receive a brain signal from the patient, derive a neurological event detection signal from the brain signal, the neurological event detection signal indicating detected neurological events in the patient, receive a cardiac signal from the patient, derive a cardiac event detection signal, the cardiac event detection signal indicating detected cardiac events in the patient, analyze timing relationships between detected neurological events and cardiac events, identify a matched event when one of the detected neurological events is temporally related to one of the detected cardiac events, determine whether the cardiac event detection signal facilitates detection of neurological events based on the matched events, cause the therapy module to deliver a therapy to the patient in response to a cardiac event if the cardiac event detection signal is determined to facilitate detection of neurological events, and change the therapy delivered to the patient based on the sensed brain signals. - View Dependent Claims (65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76)
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77. A computer-readable medium programmed with instructions for performing a method of treating a neurological disorder in a patient, the medium comprising instructions for causing a programmable processor to:
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obtain a neurological event detection signal, the neurological event detection signal indicating neurological events detected in a brain signal from the patient;
obtain a cardiac event detection signal, the cardiac event detection signal indicating detected cardiac events in the patient;
analyze timing relationships between detected neurological events and cardiac events;
identify a matched event when one of the detected neurological events is temporally related to one of the detected cardiac events;
determine whether the cardiac event detection signal facilitates detection of neurological events based on the matched events;
cause a neurological therapy to be delivered to the patient in response to a detected cardiac event if the cardiac event detection signal is determined to facilitate detection of neurological events; and
change the neurological therapy delivered to the patient based on the brain signal from the patient.
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78. A system for treating a neurological disorder in a patient, the system comprising:
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communication means for obtaining a neurological event detection signal and a cardiac event detection signal, the neurological event detection signal indicating detected neurological events in the patient, the cardiac event detection signal indicating detected cardiac events in the patient;
a processor for analyzing timing relationships between detected neurological events and cardiac events, said processor being adapted to identify a matched event when one of the detected neurological events is temporally related to one of the detected cardiac events, determine whether the cardiac event detection signal facilitates detection of neurological events based on the matched events, deliver a therapy to the patient for treating the neurological disorder in response to a detected cardiac event if the cardiac event detection signal is determined to facilitate detection of neurological events, and change the therapy delivered to the patient based on sensed brain signals from the patient.
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Specification