Transcutaneous analyte sensor

• US 20070265515A1
• Filed: 05/03/2007
• Published: 11/15/2007
• Est. Priority Date: 07/13/2004
• Status: Abandoned Application

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark, Masterson, Steve, Saint, Sean, Kline, Daniel, Neale, Paul, Thrower, James, Codd, Daniel
• Application Number:
  US11/797,521
• Publication Number:
  US 20070265515A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 2017/3492 against the outside of the body
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/045 with a separable interface unit, e.g. for communication
• CPC Class Codes: A61B 2560/063 Devices specially adapted for delivering implantable medical measuring apparatus
• CPC Class Codes: A61B 2562/18 Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/14 Devices for taking samples of blood hypodermic syringes A61M5/00; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood measuring of blood pressure A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/1411 by percutaneous method, e.g. by lancet
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/1451 for interstitial fluid
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1473 : invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/14735 : comprising an immobilised reagent
• CPC Class Codes: A61B 5/1486 : using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/14865 : invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 : Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/150022 : for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/6801 : specially adapted to be attached to or worn on the body surface
• CPC Class Codes: A61B 5/6833 : Adhesive patches
• CPC Class Codes: A61B 5/68335 : including release sheets or liners
• CPC Class Codes: A61B 5/6848 : Needles
• CPC Class Codes: A61B 5/6849 : in combination with a needle set
• CPC Class Codes: A61B 5/72 : Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61M 2005/1585 : Needle inserters
• CPC Class Codes: A61M 5/14244 : adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Claims

1-21. -21. (canceled)

22. A sensor system comprising:

an analyte sensor adapted for transcutaneous placement through a skin of a host;

a mounting unit adapted for placement adjacent to the skin of the host and configured to receive the analyte sensor; and

an electronics unit configured to operably connect to the sensor and configured to measure a signal produced by the sensor,

wherein the electronics unit is integral with the mounting unit.

23. The sensor system of claim 22, wherein the electronics unit is non-detachable from the mounting unit.

24. The sensor system of claim 22, wherein the mounting unit is flexible.

25. The sensor system of claim 22, wherein the electronics unit is configured to fit within the mounting unit.

26. The sensor system of claim 22, wherein the electronics unit and the mounting unit form a unitary structure.

27. The sensor system of claim 22, further comprising an applicator configured to position at least a portion of the sensor under the skin of the host.

28. The sensor system of claim 27, wherein the applicator is configured to be coupled to the sensor prior to sensor insertion.

29. The sensor system of claim 27, wherein the applicator is configured to be detachably removed from the sensor after sensor insertion.

30. The sensor system of claim 27, wherein the applicator is configured to transcutaneously position at least a portion of the sensor at an angle of insertion of from about 0 degrees to about 90 degrees.

31. The sensor system of claim 27, wherein the applicator is configured to transcutaneously position at least a portion of the sensor at an angle of insertion of from about 30 degrees to about 60 degrees.

32. The sensor system of claim 22, wherein the mounting unit comprises a first portion adapted for mounting on the skin of the host and a second portion configured to receive the sensor, wherein the second portion is configured to articulate relative to the first portion.

33. The sensor system of claim 22, wherein the sensor is a glucose sensor.

34. A sensor system comprising:

an analyte sensor adapted for transcutaneous placement through a skin of a host;

a mounting unit adapted for placement adjacent to the skin of the host and configured to receive the analyte sensor;

an electronics unit integral with the mounting unit, wherein the electronics unit is configured to operably connect to the sensor and to measure a signal produced by the sensor; and

an applicator configured to position at least a portion of the sensor under the skin of the host, wherein the applicator is coupled to the sensor prior to sensor insertion.

35. The sensor system of claim 34, wherein the applicator is configured to be removably detached from the sensor assembly after sensor insertion.

36. The sensor system of claim 34, wherein the signal is indicative of an analyte concentration in the host.

37. The sensor system of claim 34, wherein the electronics unit is configured to wirelessly transmit data to a receiver.

38. The sensor system of claim 34, wherein the receiver is configured to receive data from the electronics unit.

39. The sensor system of claim 34, wherein the mounting unit is flexible.

40. A sensor system comprising:

an analyte sensor adapted for transcutaneous placement through a skin of a host;

a mounting unit adapted for placement adjacent to the skin of the host and configured to receive the analyte sensor, wherein the mounting unit comprises integral sensor electronics, wherein the sensor electronics are configured to operably connect to the sensor and to measure a signal produced by the sensor; and

an applicator mounted onto the mounting unit, wherein the applicator is configured to position at least a portion of the sensor under the skin of the host, wherein the sensor electronics are configured for electrical contact with the sensor, and wherein the electronics unit is configured to transmit the signal.

41. The system of claim 40, further comprising a receiver configured to receive the signal transmitted by the sensor electronics.

42. The sensor system of claim 40, wherein the mounting unit is flexible.